Interactions of gelsolin and gelsolin-actin complexes with actin. Effects of calcium on actin nucleation, filament severing, and end blocking

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Fluorimetry study of N-(1-pyrenyl)iodoacetamide-labelled F-actin. Local structural change of actin protomer both on polymerization and on binding of heavy meromyosin.

1981 • 811 citations

The structure of F-actin and of actin filaments isolated from muscle

1963 • 560 citations

Villin is a major protein of the microvillus cystoskeleton which binds both G and F actin in a calcium-dependent manner

1980 • 444 citations

Direct measurement of actin polymerization rate constants by electron microscopy of actin filaments nucleated by isolated microvillus cores.

1981 • 298 citations

Ca2+ control of actin gelation. Interaction of gelsolin with actin filaments and regulation of actin gelation.

1980 • 260 citations

Identification of gelsolin, a Ca2+-dependent regulatory protein of actin gel-sol transformation, and its intracellular distribution in a variety of cells and tissues.

1981 • 246 citations

Ca2+ control of actin filament length. Effects of macrophage gelsolin on actin polymerization.

1981 • 217 citations

Structure and biosynthesis of cytoplasmic and secreted variants of gelsolin.

1984 • 215 citations

Polymerization of Acanthamoeba actin. Kinetics, thermodynamics, and co-polymerization with muscle actin.

1976 • 200 citations

Purification and structural properties of gelsolin, a Ca2+-activated regulatory protein of macrophages.

1980 • 189 citations

Actin-gelsolin interactions. Evidence for two actin-binding sites.

1984 • 156 citations

Direct measurement of critical concentrations and assembly rate constants at the two ends of an actin filament

1983 • 139 citations

Isolation of calcium-dependent platelet proteins that interact with actin

1981 • 128 citations

F-Actin-Depolymerizing Activity of Human Serum

1979 • 120 citations

Three-dimensional structure of actin filaments and of an actin gel made with actin-binding protein.

1983 • 120 citations

Effect of villin on the kinetics of actin polymerization

1984 • 95 citations

Characterization of brevin, a serum protein that shortens actin filaments

1981 • 92 citations

An actin-destabilizing factor is present in human plasma

1979 • 91 citations

Purification and characterization of a gelsolin-actin complex from human platelets. Evidence for Ca2+-insensitive functions.

1983 • 88 citations

Platelet activation induces the formation of a stable gelsolin-actin complex from monomeric gelsolin.

1984 • 87 citations

Brevin and vitamin D binding protein: comparison of the effects of two serum proteins on actin assembly and disassembly

1984 • 81 citations

The critical concentration of actin in the presence of ATP increases with the number concentration of filaments and approaches the critical concentration of actin.ADP.

1984 • 81 citations

Plasma actin depolymerizing factor has both calcium-dependent and calcium-independent effects on actin

1983 • 81 citations

A Ca²⁺‐dependent actin modulator from vertebrate smooth muscle

1984 • 77 citations

Treadmilling of actin

1983 • 66 citations

Muscle gelsolin: isolation from heart tissue and characterization as an integral myofibrillar protein

1984 • 49 citations

Isolation of a Ca²⁺‐Dependent Actin‐Fragmenting Protein from Brain, Spinal Cord, and Cultured Neurones

1983 • 48 citations

A 90 000-dalton actin-binding protein from platelets comparison with villin and plasma brevin

1982 • 46 citations

Steady state length distribution of F-actin under controlled fragmentation and mechanism of length redistribution following fragmentation.

1984 • 43 citations

The effect of serum vitamin D-binding protein on polymerization and depolymerization of actin is similar to the effect of profilin on actin

1983 • 20 citations

Purification and characterization of a new mammalian serum protein with the ability to inhibit actin polymerization and promote depolymerization of actin filaments

1982 • 19 citations

Influence of Dimethyl Sulphoxide on Glycine Transport in Sarcoma-180 Tumour Cells

1968 • 12 citations