Monoclonal antibodies specific for each of the two toxin binding sites of Torpedo acetylcholine receptor

A pharmacokinetic analysis program (multi) for microcomputer.

1981 • 2,465 citations

Structural homology of Torpedo californica acetylcholine receptor subunits

1983 • 798 citations

Peptide Neurotoxins from Fish-Hunting Cone Snails

1985 • 742 citations

Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence

1982 • 730 citations

Acetylcholine Receptor: An Allosteric Protein

1984 • 620 citations

Acetylcholine Receptor: Complex of Homologous Subunits

1980 • 594 citations

The Nicotinic Cholinergic Receptor: Correlation of Molecular Structure with Functional Properties

1982 • 456 citations

Cloning and sequence analysis of calf cDNA and human genomic DNA encoding α-subunit precursor of muscle acetylcholine receptor

1983 • 433 citations

Expression of functional acetylcholine receptor from cloned cDNAs

1984 • 366 citations

One-step purification of mouse monoclonal antibodies from ascitic fluid by DEAE Affi-gel blue chromatography

1982 • 322 citations

Structure and function of an acetylcholine receptor

1982 • 281 citations

Affinity-labeling of purified acetylcholine receptor from Torpedo californica

1974 • 243 citations

Equilibrium binding of [3H]tubocurarine and [3H]acetylcholine by torpedo postsynaptic membranes: stoichiometry and ligand interactions

1979 • 243 citations

Peptide toxins from Conus geographus venom.

1981 • 238 citations

Acetylcholine receptors in normal and denervated rat diaphragm muscle. II. Comparison of junctional and extrajunctional receptors

1975 • 198 citations

Acetylcholine receptor. Responses to drug binding.

1977 • 186 citations

The Molecular Neurobiology of the Acetylcholine Receptor

1986 • 186 citations

Molecular forms of acetylcholine receptor. Effects of calcium ions and a sulfhydryl reagent on the occurrence of oligomers

1977 • 185 citations

Isolation of a clone coding for the alpha-subunit of a mouse acetylcholine receptor

1985 • 169 citations

Affinity labeling of one of two α-neurotoxin binding sites in acetylcholine receptor from Torpedo californica

1978 • 163 citations

An analysis of the dose‐response relationship at voltage‐clamped frog neuromuscular junctions.

1978 • 162 citations

Relationship between reversible antagonist occupancy and the functional capacity of the acetylcholine receptor.

1981 • 158 citations

The relationship between agonist occupation and the permeability response of the cholinergic receptor revealed by bound cobra alpha-toxin.

1980 • 140 citations

The Production of a Monoclonal Antibody That Blocks the Action of a Neurite Outgrowth-promoting Factor

1983 • 137 citations

Organization of ligand binding sites at the acetylcholine receptor: a study with monoclonal antibodies

1983 • 116 citations

Stoichiometry of the Ligand-Binding Sites in the Acetylcholine-Receptor Oligomer from Muscle and from Electric Organ. Measurement by Affinity Alkylation with Bromoacetylcholine

1980 • 110 citations

Monoclonal anti-acetylcholine-receptor antibodies directed against the cholinergic binding site

1981 • 105 citations

Interaction of [125I]-.alpha.-bungarotoxin with acetylcholine receptor from Torpedo californica

1979 • 100 citations

Ligand specificity of state transitions in the cholinergic receptor: behavior of agonists and antagonists.

1979 • 89 citations

Subunit structure of the acetylcholine receptor from denervated rat skeletal muscle

1977 • 86 citations

A monoclonal antibody interfering with binding and response of the acetylcholine receptor.

1986 • 84 citations

Production of monoclonal antibodies against calmodulin by in vitro immunization of spleen cells.

1983 • 73 citations

Antibodies from myasthenic patients that compete with cholinergic agents for binding to nicotinic receptors.

1980 • 50 citations

Molecular weight and structural nonequivalence of the mature alpha subunits of Torpedo californica acetylcholine receptor.

1984 • 48 citations

A Developmental Change in the Immunological Properties of Acetylcholine Receptors at the Rat Neuromuscular Junction

1983 • 46 citations

Primary structure and binding properties of iodinated derivatives of alpha-bungarotoxin.

1980 • 45 citations

Interaction of cholinergic ligands with the purified acetylcholine receptor protein. I. Equilibrium binding studies.

1983 • 43 citations

Effects of thio-group modifications of Torpedo californica acetylcholine receptor on ion flux activation and inactivation kinetics

1984 • 41 citations

Monoclonal antibodies to Torpedo acetylcholine receptor. Characterisation of antigenic determinants within the cholinergic binding site

1985 • 39 citations

Allosteric interactions of the membrane-bound acetylcholine receptor; kinetic studies with α-bungarotoxin

1975 • 38 citations

The occurrence of long openings in the purified cholinergic receptor channel increases with acetylcholine concentration

1985 • 38 citations

Arrangement of the subunits of the nicotinic acetylcholine receptor of Torpedo californica as determined by .alpha.-neurotoxin crosslinking

1985 • 38 citations

Monoclonal antibodies as probes of the alpha-bungarotoxin and cholinergic binding regions of the acetylcholine receptor.

1987 • 34 citations

Modification of alpha-bungarotoxin and cholinergic ligand-binding properties of Torpedo acetylcholine receptor by a monoclonal anti-acetylcholine receptor antibody.

1984 • 29 citations

Equilibrium binding of cholinergic ligands to the membrane-bound acetylcholine receptor.

1986 • 28 citations

Structural heterogeneity of the .alpha. subunits of the nicotinic acetylcholine receptor in relation to agonist affinity alkylation and antagonist binding

1986 • 27 citations

The effects of a myasthenic serum on the acetylcholine receptors of C2 myotubes. I. Immunological distinction between the two toxin-binding sites of the receptor.

1985 • 20 citations

A single gene codes for the nicotinic acetylcholine receptor alpha-subunit in Torpedo marmorata: structural and developmental implications.

1984 • 19 citations

Interrelationship of carbohydrate and the α-toxin binding site on the acetylcholine receptor from

1980 • 17 citations

Covalent coupling of antigens to chemically activated lipopolysaccharide: a tool for in vivo and in vitro specific B cell stimulation

1983 • 5 citations