The effects of a myasthenic serum on the acetylcholine receptors of C2 myotubes. I. Immunological distinction between the two toxin-binding sites of the receptor.

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

1977 • 2,070 citations

Autoimmune Response to Acetylcholine Receptor

1973 • 1,019 citations

Primary structure of α-subunit precursor of Torpedo californica acetylcholine receptor deduced from cDNA sequence

1982 • 730 citations

Acetylcholine Receptor: An Allosteric Protein

1984 • 620 citations

Acetylcholine Receptor: Complex of Homologous Subunits

1980 • 594 citations

Cloning and sequence analysis of calf cDNA and human genomic DNA encoding α-subunit precursor of muscle acetylcholine receptor

1983 • 433 citations

Myasthenia Gravis: Passive Transfer from Man to Mouse

1975 • 430 citations

Functional Activities of Autoantibodies to Acetylcholine Receptors and the Clinical Severity of Myasthenia Gravis

1982 • 384 citations

Serum Globulin in Myasthenia Gravis: Inhibition of α-Bungarotoxin Binding to Acetylcholine Receptors

1974 • 365 citations

Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies.

1982 • 342 citations

Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain.

1983 • 332 citations

Immunology of acetylcholine receptors in relation to myasthenia gravis.

1980 • 255 citations

Equilibrium binding of [3H]tubocurarine and [3H]acetylcholine by torpedo postsynaptic membranes: stoichiometry and ligand interactions

1979 • 243 citations

Fluorescent tetramethyl rhodamine derivatives of α-bungarotoxin: Preparation, separation, and characterization

1977 • 234 citations

MYASTHENIA GRAVIS: A SERUM FACTOR BLOCKING ACETYLCHOLINE RECEPTORS OF THE HUMAN NEUROMUSCULAR JUNCTION

1975 • 185 citations

The molecular cloning and characterisation of cDNA coding for the α subunit of the acetyl-choline receptor

1982 • 176 citations

Relationship between reversible antagonist occupancy and the functional capacity of the acetylcholine receptor.

1981 • 158 citations

Anti-acetylcholine receptor antibodies.

1980 • 151 citations

The relationship between agonist occupation and the permeability response of the cholinergic receptor revealed by bound cobra alpha-toxin.

1980 • 140 citations

Restoration of 125I-alpha-bungarotoxin binding activity to the alpha subunit of Torpedo acetylcholine receptor isolated by gel electrophoresis in sodium dodecyl sulfate.

1981 • 128 citations

The Biology of Myasthenia Gravis

1981 • 122 citations

Binding of alpha-bungarotoxin to isolated alpha subunit of the acetylcholine receptor of Torpedo californica: quantitative analysis with protein blots.

1983 • 113 citations

Stoichiometry of the Ligand-Binding Sites in the Acetylcholine-Receptor Oligomer from Muscle and from Electric Organ. Measurement by Affinity Alkylation with Bromoacetylcholine

1980 • 110 citations

No direct correlation between serum antiacetylcholine receptor antibody levels and clinical state of individual patients with myasthenia gravis

1981 • 100 citations

Developmental regulation of 16S acetylcholinesterase and acetylcholine receptors in a mouse muscle cell line

1983 • 94 citations

Interaction of myasthenic serum globulin with the acetylcholine receptor

1975 • 90 citations

Mammalian Muscle Acetylcholine Receptor: A Supramolecular Structure Formed by Four Related Proteins

1982 • 88 citations

Functional consequences of agonist-mediated state transitions in the cholinergic receptor

1979 • 60 citations

Analysis of receptor-ligand interactions using nitrocellulose gel transfer: Application to Torpedo acetylcholine receptor and alpha-bungarotoxin

1983 • 54 citations

Molecular weight and structural nonequivalence of the mature alpha subunits of Torpedo californica acetylcholine receptor.

1984 • 48 citations

Equilibrium Binding of Acetylcholine to the Membrane-Bound Acetylcholine Receptor

1982 • 46 citations

A Developmental Change in the Immunological Properties of Acetylcholine Receptors at the Rat Neuromuscular Junction

1983 • 46 citations

A postnatal change in the immunological properties of the acetylcholine receptor at rat muscle endplates

1985 • 38 citations

Immunoglobulins in myasthenia gravis: effect of human lymph IgG 3 and F(ab‘)₂ fragments on a cholinergic receptor preparation from Torpedo marmorata*

1977 • 30 citations

Immunochemical properties of junctional and extrajunctional acetylcholine receptor

1981 • 25 citations

A single gene codes for the nicotinic acetylcholine receptor alpha-subunit in Torpedo marmorata: structural and developmental implications.

1984 • 19 citations

Differences in the interaction of acetylcholine receptor antibodies with receptor from normal, denervated and myasthenic human muscle.

1982 • 18 citations

The effects of a myasthenic serum on the acetylcholine receptors of C2 myotubes. II. Functional inactivation of the receptor

1985 • 15 citations

Myasthenia Gravis and the Nicotinic Cholinergic Receptor

1981 • 12 citations

Regulation of acetylcholine receptors in the mouse muscle cell line, C2*1

1984 • 9 citations

Heterogeneity of acetylcholine receptors: different forms of receptor distinguished by alpha-bungarotoxin kinetics and by antibody binding properties.

1983 • 3 citations