Methamphetamine‐induced neurotoxicity: Roles for glutamate and dopamine efflux

Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.

1973 • 1,272 citations

Long-lasting depletions of striatal dopamine and loss of dopamine uptake sites following repeated administration of methamphetamine

1980 • 533 citations

Role for Excitatory Amino Acids in Methamphetamine-Induced Nigrostriatal Dopaminergic Toxicity

1989 • 495 citations

Long-term effects of repeated methylamphetamine administration on dopamine and serotonin neurons in the rat brain: A regional study

1980 • 492 citations

Dopamine nerve terminal degeneration produced by high doses of methylamphetamine in the rat brain

1982 • 480 citations

Long-term effects of multiple doses of methamphetamine on tryptophan hydroxylase and tyrosine hydroxylase activity in rat brain.

1980 • 444 citations

Dopamine can be released by two mechanisms differentially affected by the dopamine transport inhibitor nomifensine.

1979 • 382 citations

Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3, 4-methylenedioxymethamphetamine

1992 • 357 citations

An improved and rapid HPLC-EC method for the isocratic separation of amino acid neurotransmitters from brain tissue and microdialysis perfusates

1988 • 349 citations

Dopamine release and metabolism in awake rats after systemic neuroleptics as studied by trans-striatal dialysis

1985 • 314 citations

Long-term methamphetamine induced changes in brain catecholamines in tolerant rhesus monkeys

1976 • 307 citations

Role of dopamine in the neurotoxic effects of methamphetamine.

1985 • 299 citations

Dopaminergic Modulation of Glutamate Release in Striatum as Measured by Microdialysis

1992 • 225 citations

N-methyl-D-aspartate-induced neuronal activation is selectively modulated by σ receptors

1990 • 225 citations

Formation of 6-hydroxydopamine in caudate nucleus of the rat brain after a single large dose of methylamphetamine

1984 • 224 citations

Naloxone-inaccessible sigma receptor in rat central nervous system.

1983 • 214 citations

Pre- and Postsynaptic Neurotoxic Effects of Dopamine Demonstrated by Intrastriatal Injection

1993 • 204 citations

Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice.

1991 • 186 citations

Multiple methamphetamine injections induce marked increases in extracellular striatal dopamine which correlate with subsequent neurotoxicity

1991 • 183 citations

In vivo electrophysiological evidence for a selective modulation of N-methyl-D-aspartate-induced neuronal activation in rat CA3 dorsal hippocampus by sigma ligands.

1992 • 173 citations

Comparison of the release of [3h]dopamine from isolated corpus striatum by amphetamine, fenfluramine and unlabelled dopamine

1982 • 151 citations

Roles of D1 and D2 dopamine receptor subtypes in mediating the methamphetamine-induced changes in monoamine systems.

1986 • 145 citations

Dopamine uptake inhibitors block long-term neurotoxic effects of methamphetamine upon dopaminergic neurons

1990 • 127 citations

Role of the dopamine uptake carrier in the neurochemical response to methamphetamine: Effects of amfonelic acid

1985 • 124 citations

Effects of a cold environment or age on methamphetamine-induced dopamine release in the caudate putamen of female rats

1993 • 106 citations

Methamphetamine‐Induced Dopamine Overflow and Injury to Striatal Dopamine Terminals: Attenuation by Dopamine D₁ or D₂ Antagonists

1993 • 104 citations

A neurochemical heterogeneity of the rat striatum as measured by in vivo electrochemistry and microdialysis

1990 • 103 citations

Effect of acute and chronic methamphetamine treatment on tyrosine hydroxylase activity in brain and adrenal medulla

1971 • 100 citations

High glutamate concentrations evoke Ca(++)-independent dopamine release from striatal slices: a possible role of reverse dopamine transport.

1991 • 97 citations

MK-801 attenuates the dopamine-releasing but not the behavioral effects of methamphetamine: an in vivo microdialysis study

1991 • 92 citations

MK‐801 protection against methamphetamine‐induced striatal dopamine terminal injury is associated with attenuated dopamine overflow

1992 • 77 citations

Influence of methamphetamine and neuroleptic drugs on tyrosine hydroxylase activity

1974 • 74 citations

α-Methyl-p-tyrosine pretreatment partially prevents methamphetamine-induced endogenous neurotoxin formation

1990 • 73 citations

Striatal dopamine release in vivo following neurotoxic doses of methamphetamine and effect of the neuroprotective drugs, chlormethiazole and dizocilpine

1993 • 65 citations

Haloperidol interacts with the strychnine-insensitive glycine site at the NMDA receptor in cultured mouse hippocampal neurones

1993 • 58 citations

Effect of D-amphetamine on the extracellular concentrations of glutamate and dopamine in iprindole-treated rats

1993 • 53 citations

Interactions of MK-801 with glutamate-, glutamine- and methamphetamine-evoked release of [3H]dopamine from striatal slices.

1991 • 48 citations

Repeated methamphetamine-treatment alters brain δ receptors

1993 • 39 citations

Accelerated communication GBR-12909 and fluspirilene potently inhibited binding of [3H] (+) 3-PPP to sigma receptors in rat brain

1990 • 30 citations

The new generation of antipsychotic drugs

1996 • 30 citations

Protection against amphetamine-induced neurotoxicity toward striatal dopamine neurons in rodents by LY274614, an excitatory amino acid antagonist

1992 • 28 citations

MK-801, but not drugs acting at strychnine-insensitive glycine receptors, attenuate methamphetamine nigrostriatal toxicity

1993 • 21 citations

MK-801 fails to modify the effect of methamphetamine on dopamine release in the rat striatum

1991 • 16 citations