N-methyl-D-aspartate-induced neuronal activation is selectively modulated by σ receptors

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

1986 • 1,814 citations

Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors

1984 • 824 citations

1,3-Di(2-[5-3H]tolyl)guanidine: a selective ligand that labels sigma-type receptors for psychotomimetic opiates and antipsychotic drugs.

1986 • 379 citations

Sigma and phencyclidine-like compounds as molecular probes in biology

1988 • 251 citations

Receptor mechanisms in antipsychotic drug action: focus on sigma receptors

1989 • 138 citations

Neocortical epileptogenesis in vitro: studies with N-methyl-D-aspartate, phencyclidine, sigma and dextromethorphan receptor ligands.

1989 • 97 citations

Comparison of the actions of phencyclidine and sigma ligands on CA1 hippocampal pyramidal neurons in the rat

1988 • 31 citations

Phencyclidine receptors and N-methyl-D-aspartate antagonsim: Electrophysiologic data correlates with known behaviours

1988 • 27 citations