Advanced glycation end products‐induced apoptosis attenuated by PPARδ activation and epigallocatechin gallate through NF‐κB pathway in human embryonic kidney cells and human mesangial cells

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

1993 • 4,414 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

Advanced Glycation End Products

2006 • 2,077 citations

Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins

1994 • 1,311 citations

ADVANCED PROTEIN GLYCOSYLATION IN DIABETES AND AGING

1995 • 1,277 citations

Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study

1996 • 708 citations

Therapeutic Roles of Peroxisome Proliferator–Activated Receptor Agonists

2005 • 634 citations

Dietary Flavonoids, Antioxidant Vitamins, and Incidence of Stroke

1996 • 506 citations

The potential role of green tea catechins in the prevention of the metabolic syndrome – A review

2009 • 364 citations

Requirement for p38 and p44/p42 Mitogen-Activated Protein Kinases in RAGE-Mediated Nuclear Factor-κB Transcriptional Activation and Cytokine Secretion

2001 • 327 citations

Alzheimer's disease – synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts

1998 • 292 citations

Peroxisome proliferator-activated receptors (PPARs): Novel therapeutic targets in renal disease

2001 • 291 citations

Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans

1997 • 221 citations

Increased proinflammatory endothelial response to S100A8/A9 after preactivation through advanced glycation end products.

2006 • 183 citations

Taurine prevents arsenic-induced cardiac oxidative stress and apoptotic damage: Role of NF-κB, p38 and JNK MAPK pathway

2009 • 171 citations

Peroxisome Proliferator-Activated Receptor Family and Its Relationship to Renal Complications of the Metabolic Syndrome

2004 • 168 citations

Chemoprotective Mechanism of the Natural Compounds, Epigallocatechin- 3-O-Gallate, Quercetin and Curcumin Against Cancer and Cardiovascular Diseases

2009 • 163 citations

Therapeutic Potential of (-)-Epigallocatechin 3-O-Gallate on Renal Damage in Diabetic Nephropathy Model Rats

2006 • 162 citations

Expression of peroxisomal proliferator-activated receptors and retinoid X receptors in the kidney

1999 • 162 citations

Cardiac peroxisome proliferator-activated receptor γ is essential in protecting cardiomyocytes from oxidative damage

2007 • 152 citations

PPAR expression and function during vertebrate development.

2002 • 140 citations

Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library

1997 • 109 citations

Peroxisome proliferator-activated receptor δ (PPARδ) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis

2005 • 99 citations

Neuroprotective effect of epigallocatechin-3-gallate against β-amyloid-induced oxidative and nitrosative cell death via augmentation of antioxidant defense capacity

2009 • 88 citations

Peroxisome Proliferator-Activated Receptor γ Down-Regulates Receptor for Advanced Glycation End Products and Inhibits Smooth Muscle Cell Proliferation in a Diabetic and Nondiabetic Rat Carotid Artery Injury Model

2005 • 85 citations

Effects of Epigallocatechin-3-gallate on lead-induced oxidative damage

2008 • 85 citations

The Thiazolidinedione Insulin Sensitiser, BRL 49653, Increases the Expression of PPAR-γ and aP2in Adipose Tissue of High-Fat-Fed Rats

1996 • 76 citations

Activation of PPAR-δ in isolated rat skeletal muscle switches fuel preference from glucose to fatty acids

2006 • 75 citations

Protective Effect of (-)-Epigallocatechin Gallate against Advanced Glycation Endproducts-Induced Injury in Neuronal Cells

2007 • 74 citations

(-)-Epigallocatechin gallate induced apoptosis in human adrenal cancer NCI-H295 cells through caspase-dependent and caspase-independent pathway.

2009 • 70 citations

Ablation of the gene encoding p66Shc protects mice against AGE-induced glomerulopathy by preventing oxidant-dependent tissue injury and further AGE accumulation

2007 • 64 citations

Peroxisome proliferator-activated receptor-α activator fenofibrate prevents high-fat diet-induced renal lipotoxicity in spontaneously hypertensive rats

2009 • 63 citations

Enhanced RAGE-mediated NFκB stimulation in inflamed hemodialysis patients

2005 • 62 citations

Advanced Glycation End Product-Induced Peroxisome Proliferator-Activated Receptor γ Gene Expression in the Cultured Mesangial Cells

1999 • 56 citations

Peroxisome Proliferator-Activated Receptor δ Regulates Extracellular Matrix and Apoptosis of Vascular Smooth Muscle Cells Through the Activation of Transforming Growth Factor-β1/Smad3

2009 • 55 citations

Therapeutic Strategies in the Treatment of Diabetic Nephropathy - a Translational Medicine Approach

2009 • 49 citations

Nifedipine, a calcium channel blocker, inhibits advanced glycation end product (AGE)-elicited mesangial cell damage by suppressing AGE receptor (RAGE) expression via peroxisome proliferator-activated receptor-gamma activation

2009 • 47 citations

Telmisartan Inhibits Advanced Glycation End Products (AGEs)-Elicited Endothelial Cell Injury by Suppressing AGE Receptor (RAGE) Expression Via Peroxisome Proliferator-Activated Receptor-γ Activation

2008 • 44 citations

Regulation of Cytochrome P-450 4A Activity by Peroxisome Proliferator-Activated Receptors in the Rat Kidney

2003 • 41 citations

Advanced Glycation Endproducts Induce Changes in Glucose Consumption, Lactate Production, and ATP Levels in SH-SY5Y Neuroblastoma Cells by a Redox-Sensitive Mechanism

2003 • 28 citations

Cytotoxicity of advanced glycation endproducts in human micro- and astroglial cell lines depends on the degree of protein glycation

2008 • 19 citations