Peroxisome proliferator-activated receptor δ (PPARδ) activation protects H9c2 cardiomyoblasts from oxidative stress-induced apoptosis

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1990 • 3,462 citations

Atherosclerosis

2001 • 2,982 citations

Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.

1994 • 1,410 citations

A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport

2001 • 1,050 citations

Activation of Proliferator-activated Receptors α and γ Induces Apoptosis of Human Monocyte-derived Macrophages

1998 • 914 citations

Endothelial Cell Apoptosis Induced by the Peroxisome Proliferator-activated Receptor (PPAR) Ligand 15-Deoxy-Δ12,14-prostaglandin J2

1999 • 440 citations

Peroxisome Proliferator-Activated Receptor (PPAR) α and PPARβ/δ, but not PPARγ, Modulate the Expression of Genes Involved in Cardiac Lipid Metabolism

2003 • 402 citations

Antiapoptotic Role of PPARβ in Keratinocytes via Transcriptional Control of the Akt1 Signaling Pathway

2002 • 334 citations

Glutaredoxin Exerts an Antiapoptotic Effect by Regulating the Redox State of Akt

2003 • 290 citations

The ligands/activators for peroxisome proliferator-activated receptor α (PPARα) and PPARγ increase Cu2+, Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells

2001 • 284 citations

Right and Left Myocardial Antioxidant Responses During Heart Failure Subsequent to Myocardial Infarction

1997 • 271 citations

Identification of a Functional Peroxisome Proliferator-Activated Receptor Response Element in the Rat Catalase Promoter

2002 • 252 citations

PPARα Activator Effects on Ang II–Induced Vascular Oxidative Stress and Inflammation

2002 • 236 citations

Increased malondialdehyde in peripheral blood of patients with congestive heart failure

1996 • 212 citations

Pioglitazone Prevents Hypertension and Reduces Oxidative Stress in Diet-Induced Obesity

2003 • 185 citations

PPARγ activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes

2004 • 171 citations

Ceramide and Reactive Oxygen Species Generated by H2O2 Induce Caspase-3-independent Degradation of Akt/Protein Kinase B

2002 • 170 citations

Antioxidative, Antinitrative, and Vasculoprotective Effects of a Peroxisome Proliferator–Activated Receptor-γ Agonist in Hypercholesterolemia

2003 • 165 citations

Apoptosis in relevant clinical situations contribution of apoptosis in myocardial infarction

2000 • 164 citations

Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha)

1998 • 141 citations

Regulation of Protein Kinase B and 4E-BP1 by Oxidative Stress in Cardiac Myocytes

2000 • 136 citations

Anti-apoptotic effects of rosiglitazone in hypercholesterolemic rabbits subjected to myocardial ischemia and reperfusion

2004 • 123 citations

Hydrogen Peroxide Dose Dependent Induction of Cell Death or Hypertrophy in Cardiomyocytes

2000 • 117 citations

Time Course of the Apoptotic Cascade and Effects of Caspase Inhibitors in Adult Rat Ventricular Cardiomyocytes

2001 • 100 citations

Bezafibrate has an antioxidant effect: Peroxisome proliferator-activated receptor α is associated with Cu2+, Zn2+-superoxide dismutase in the liver

1998 • 100 citations

Alterations of Peroxisome Proliferator-activated Receptor δ Activity Affect Fatty Acid-controlled Adipose Differentiation

2000 • 99 citations

Sequential inactivation of reactive oxygen species by combined overexpression of SOD isoforms and catalase in insulin-producing cells

2003 • 80 citations

Differential vulnerability to oxidative stress in rat cardiac myocytes versus fibroblasts

2001 • 65 citations

REACTIVE OXYGEN SPECIES INDUCE CARDIOMYOCYTE APOPTOSIS PARTLY THROUGH TNF-α

2002 • 51 citations

The effect of peroxisome proliferator-activated receptors alpha (PPARalpha) agonist, fenofibrate, on lipid peroxidation, total antioxidant capacity, and plasma paraoxonase 1 (PON 1) activity.

2002 • 44 citations

Characteristics of death of neonatal rat cardiomyocytes following hypoxia or hypoxia-reoxygenation: the association of apoptosis and cell membrane disintegrity

2002 • 20 citations