Anthrax toxin triggers endocytosis of its receptor via a lipid raft–mediated clathrin-dependent process
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References (45)
Functional rafts in cell membranes
1997 • 9,471 citations
Lipid rafts and signal transduction
2000 • 6,079 citations
Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton
2013 • 2,950 citations
FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANES
1998 • 2,942 citations
Genes Expressed in Human Tumor Endothelium
2000 • 1,838 citations
Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER
2001 • 1,236 citations
Induction of mutant dynamin specifically blocks endocytic coated vesicle formation.
1994 • 1,206 citations
Lipid Domain Structure of the Plasma Membrane Revealed by Patching of Membrane Components
1998 • 1,193 citations
Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor
1998 • 1,003 citations
Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells.
1982 • 929 citations
Identification of the cellular receptor for anthrax toxin
2001 • 848 citations
Crystal structure of the anthrax toxin protective antigen
1997 • 755 citations
Endocytosis Via Caveolae
2002 • 708 citations
Membrane microdomains and caveolae
1999 • 580 citations
Flotillin and Epidermal Surface Antigen Define a New Family of Caveolae-associated Integral Membrane Proteins
1997 • 549 citations
Sourcebook of bacterial protein toxins
1991 • 537 citations
A Role for Lipid Rafts in B Cell Antigen Receptor Signaling and Antigen Targeting
1999 • 473 citations
Inhibition of clathrin-coated pit assembly by an Eps15 mutant
1999 • 424 citations
Anthrax Lethal Factor Cleaves the N-Terminus of MAPKKs and Induces Tyrosine/Threonine Phosphorylation of MAPKs in Cultured Macrophages
1998 • 402 citations
Anthrax protective antigen forms oligomers during intoxication of mammalian cells.
1994 • 399 citations
Regulated Interactions between Dynamin and the Actin-Binding Protein Cortactin Modulate Cell Shape
2000 • 391 citations
Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor
2000 • 342 citations
Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases
1995 • 253 citations
Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction
2002 • 239 citations
Differential sorting and fate of endocytosed GPI-anchored proteins
2002 • 221 citations
Lipid Rafts Unite Signaling Cascades with Clathrin to Regulate BCR Internalization
2002 • 216 citations
Retrieval of TGN proteins from the cell surface requires endosomal acidification.
1994 • 189 citations
Mammalian Cell Mutants Resistant to a Sphingomyelin-directed Cytolysin
1998 • 181 citations
Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen
2002 • 174 citations
VIP21/caveolin, glycosphingolipid clusters and the sorting of glycosylphosphatidylinositol-anchored proteins in epithelial cells.
1994 • 166 citations
Targeting of Tumor Cells by Cell Surface Urokinase Plasminogen Activator-dependent Anthrax Toxin
2001 • 164 citations
[16] Production and purification of anthrax toxin
1988 • 160 citations
Plasma Membrane Microdomains Act as Concentration Platforms to Facilitate Intoxication by Aerolysin
1999 • 155 citations
Cell Surface Tumor Endothelium Marker 8 Cytoplasmic Tail-independent Anthrax Toxin Binding, Proteolytic Processing, Oligomer Formation, and Internalization
2003 • 148 citations
A Mammalian Homolog of the Yeast LCB1 Encodes a Component of Serine Palmitoyltransferase, the Enzyme Catalyzing the First Step in Sphingolipid Synthesis
1997 • 142 citations
Adventures of a pore-forming toxin at the target cell surface
2000 • 131 citations
Proteasome Activity Is Required for Anthrax Lethal Toxin To Kill Macrophages
1999 • 120 citations
Proteolytic activation of receptor-bound anthrax protective antigen on macrophages promotes its internalization
2000 • 103 citations
The chymotrypsin-sensitive site, FFD315, in anthrax toxin protective antigen is required for translocation of lethal factor.
1994 • 97 citations
Involvement of Domain 3 in Oligomerization by the Protective Antigen Moiety of Anthrax Toxin
2001 • 92 citations
2001: a year of major advances in anthrax toxin research
2002 • 74 citations
Cell Surface Dynamics of GPI-Anchored Proteins
1997 • 58 citations
Quickening the pace of anthrax research: three advances point towards possible therapies
2002 • 39 citations
Anthrax Toxin Entry into Polarized Epithelial Cells
1999 • 38 citations
Caveolin isoforms in resident and elicited rat peritoneal macrophages
2000 • 28 citations