Endothelin-1 in Adult Respiratory Distress Syndrome

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

An Expanded Definition of the Adult Respiratory Distress Syndrome

1988 • 2,636 citations

Inhaled Nitric Oxide for the Adult Respiratory Distress Syndrome

1993 • 1,811 citations

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

1988 • 1,417 citations

Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction.

1991 • 1,134 citations

Increased Plasma Endothelin-1 in Pulmonary Hypertension: Marker or Mediator of Disease?

1991 • 983 citations

Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock

1991 • 873 citations

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium.

1991 • 691 citations

Elevated Plasma Endothelin-1 Concentrations Are Associated with the Severity of Illness in Patients with Sepsis

1991 • 227 citations

Effect of endothelin-1 in man.

1990 • 225 citations

Regulation of sarcoplasmic reticulum gene expression during cardiac and skeletal muscle development

1992 • 216 citations

ENDOTHELIN: AN IMPORTANT FACTOR IN ACUTE RENAL FAILURE?

1988 • 214 citations

The Fate of Circulating Amines Within the Pulmonary Circulation

1982 • 147 citations

Endothelin: A New Cardiovascular Regulatory Peptide

1990 • 133 citations

Acute pulmonary alveolar hypoxia increases lung and plasma endothelin-1 levels in conscious rats

1991 • 132 citations

Tissue distribution and half-life of 125 I-endothelin in the rat: Importance of pulmonary clearance

1990 • 117 citations

Tissue specific distribution, clearance and vascular effects of endothelin in the pig

1989 • 110 citations

Increased plasma and pulmonary lymph levels of endothelin during endotoxin shock

1989 • 102 citations

Mechanism of endothelin-1-induced pulmonary vasoconstriction.

1991 • 89 citations

Regional effects and clearance of endothelin‐1 across pulmonary and splanchnic circulation

1992 • 76 citations

Endothelin-1 stimulates arachidonate 15-lipoxygenase activity and oxygen radical formation in the rat distal lung

1990 • 70 citations

THE PATHOPHYSIOLOGIC ROLE OF ENDOTHELIN IN ACUTE VASCULAR REJECTION AFTER RENAL TRANSPLANTATION

1991 • 40 citations

Plasma concentrations of endothelin in man: arterio‐venous differences and release during venous stasis

1990 • 32 citations

Phosphoramidon abolishes the increases in endothelin-1 release induced by ischemia-hypoxia in isolated perfused guinea pig lungs.

1992 • 28 citations

Uptake and Metabolism of Endothelin in the Isolated Perfused Rat Lung

1990 • 26 citations

Occurrence and effects of endothelin in guinea‐pig cardiopulmonary tissue

1990 • 21 citations

Analysis of responses to endothelins 1, 2, and 3 and sarafotoxin 6b in airways of the cat

1991 • 11 citations

Pharmacological modulation of 2-methyl-carbamate-PAF induced rat paw oedema

1990 • 8 citations