Regional effects and clearance of endothelin‐1 across pulmonary and splanchnic circulation

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

1989 • 2,551 citations

Catheterization of the Heart in Man with Use of a Flow-Directed Balloon-Tipped Catheter

1970 • 2,092 citations

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

1988 • 1,417 citations

Molecular biology and biochemistry of the endothelins

1989 • 620 citations

Indocyanine Green Clearance and Estimated Hepatic Blood Flow during Mild to Maximal Exercise in Upright Man *

1964 • 396 citations

Immunoreactive endothelin in human plasma: Marked elevations in patients in cardiogenic shock

1989 • 330 citations

PLASMA ENDOTHELIN LEVELS IN PATIENTS WITH URAEMIA

1989 • 292 citations

Cardiovascular, renal, and endocrine responses to intravenous endothelin in conscious dogs

1988 • 279 citations

Presence of immunoreactive endothelin in human plasma

1989 • 258 citations

Effect of endothelin-1 in man.

1990 • 225 citations

Regional vasodilation is a prominent feature of the haemodynamic response to endothelin in anaesthetized, spontaneously hypertensive rats

1988 • 199 citations

Insulin production rate following glucose ingestion estimated by splanchnic C-peptide output in normal man

1979 • 148 citations

Endothelin produces pulmonary vasoconstriction and systemic vasodilation

1989 • 124 citations

Tissue specific distribution, clearance and vascular effects of endothelin in the pig

1989 • 110 citations

Endothelin - a new family of endothelium-derived peptides with widespread biological properties

1989 • 93 citations

Regional Hemodynamic Effects and Clearance of Endothelin-1 in Humans

1992 • 72 citations

Effects of endothelin on regional hemodynamics in conscious rats

1989 • 56 citations

Increased plasma levels of endothelin‐like immunoreactivity during endotoxin administration in the pig

1989 • 54 citations

Plasma concentrations of endothelin in man: arterio‐venous differences and release during venous stasis

1990 • 52 citations

Plasma concentrations of endothelin in man: arterio‐venous differences and release during venous stasis

1990 • 32 citations