Uptake and Metabolism of Endothelin in the Isolated Perfused Rat Lung

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

1988 • 1,417 citations

Characterization of a coronary vasoconstrictor produced by cultured endothelial cells

1985 • 616 citations

Abundance of endothelin-3 in rat intestine, pituitary gland and brain

1989 • 346 citations

Endothelin action on vascular smooth muscle involves inositol trisphosphate and calcium mobilization

1989 • 346 citations

Autoradiographic distribution in rat tissues of binding sites for endothelin: a neuropeptide?

1989 • 299 citations

Presence of immunoreactive endothelin in human plasma

1989 • 258 citations

Structure-activity relationships of endothelin: Importance of the C-terminal moiety

1988 • 220 citations

Binding and receptor down‐regulation of a novel vasoconstrictor endothelin in cultured rat vascular smooth muscle cells

1988 • 215 citations

Endothelial cells in culture produce a vasoconstrictor substance

1987 • 195 citations

Cl-dependent K transport in a pure population of volume-regulating human erythrocytes

1989 • 187 citations

Sustained coronary vasoconstriction provoked by a peptidergic substance released from endothelial cells in culture.

1986 • 177 citations

Stimulation of Phosphatidylinositol Hydrolysis, Diacylglycerol Release, and Gene Expression in Response to Endothelin, a Potent New Agonist for Fibroblasts and Smooth Muscle Cells

1989 • 166 citations

Endothelin action: Inhibition by a protein kinase C inhibitor and involvement of phosphoinositols

1989 • 154 citations

RADIOAUTOGRAPHIC DEMONSTRATION OF 5-HYDROXYTRYPTAMINE-3H UPTAKE BY PULMONARY ENDOTHELIAL CELLS

1972 • 150 citations

The Fate of Radioiodinated Endothelin-1 and Endothelin-3 in the Rat

1989 • 149 citations

Competitive interaction between endothelin and sarafotoxin: Binding and phosphoinositides hydrolysis in rat atria and brain

1989 • 143 citations

Endothelin produces pulmonary vasoconstriction and systemic vasodilation

1989 • 124 citations

Elimination of Intravenously Injected Endothelin-1 from the Circulation of the Rat

1989 • 112 citations

Tissue specific distribution, clearance and vascular effects of endothelin in the pig

1989 • 110 citations

The uptake and disposition of dl-norepinephrine in perfused rat lung.

1969 • 109 citations

Specific binding of endothelin on human vascular smooth muscle cells in culture.

1989 • 103 citations

Increase vs. decrease of calcium uptake by isolated heart cells induced by H2O2 vs. HOCl

1989 • 58 citations

Effects of endothelin on regional hemodynamics in conscious rats

1989 • 56 citations

Receptor binding activity and cytosolic free calcium response by synthetic endothelin analogs in cultured rat vascular smooth muscle cells

1989 • 53 citations

Endothelin binding sites in porcine‐aortic and rat lung membranes

1989 • 52 citations

Pulmonary Metabolism of Prostaglandins and Vasoactive Peptides

1982 • 46 citations

The direct observation of arteriolar constriction induced by endothelin in vivo

1989 • 36 citations

Red blood cells but not platelets prolong vascular reactivity of isolated rat lungs

1978 • 32 citations

Analysis of regional responses to endothelin in hindquarters vascular bed of cats

1989 • 30 citations

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