Human Mitochondrial Thioredoxin

Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections.

1991 • 2,598 citations

Physiological functions of thioredoxin and thioredoxin reductase

2000 • 2,440 citations

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1

1998 • 2,360 citations

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

1999 • 2,157 citations

Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis

1997 • 1,851 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Mitochondrial control of nuclear apoptosis.

1996 • 1,363 citations

Activation of Hypoxia-inducible Transcription Factor Depends Primarily upon Redox-sensitive Stabilization of Its α Subunit

1996 • 1,172 citations

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.

1996 • 1,143 citations

Thiordoxin regulates the DNA binding activity of NF-χB by reduction of a disulphid bond involving cysteine 62

1992 • 825 citations

The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents

1994 • 527 citations

Topoisomerase Poisons: Harnessing the Dark Side of Enzyme Mechanism

1995 • 501 citations

Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells

1995 • 493 citations

Properties and Biological Activities of Thioredoxins

2001 • 437 citations

Cloning and Expression of a Novel Mammalian Thioredoxin

1997 • 391 citations

Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis

2002 • 321 citations

Crystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiber

2002 • 277 citations

The Mitochondrial F0F1-ATPase Proton Pump Is Required for Function of the Proapoptotic Protein Bax in Yeast and Mammalian Cells

1998 • 273 citations

The effect of H2O2 upon thioredoxin-enriched lens epithelial cells.

1988 • 214 citations

Membrane protein thiol cross-linking associated with the permeabilization of the inner mitochondrial membrane by Ca2+ plus prooxidants.

1990 • 198 citations

Role of the Mitochondrial Membrane Permeability Transition (MPT) in Rotenone-Induced Apoptosis in Liver Cells

2000 • 181 citations

ATP converts necrosis to apoptosis in oxidant-injured endothelial cells

1998 • 167 citations

The role of thioredoxin reductase in the reduction of free radicals at the surface of the epidermis

1986 • 165 citations

SP‐22 is a Thioredoxin‐Dependent Peroxide Reductase in Mitochondria

1997 • 159 citations

The γ‐subunit of ATP synthase from spinach chloroplasts Primary structure deduced from the cloned cDNA sequence

1988 • 156 citations

Distinct Pathways for Stimulation of Cytochrome cRelease by Etoposide

2000 • 155 citations

Spontaneous Changes in Mitochondrial Membrane Potential in Cultured Neurons

2001 • 153 citations

Expression and growth-promoting effect of adult t-cell leukemia-derived factor a human thioredoxin homologue in hepatocellular carcinoma

1992 • 145 citations

The Participation of Reactive Oxygen Species and Protein Thiols in the Mechanism of Mitochondrial Inner Membrane Permeabilization by Calcium plus Prooxidants

1993 • 139 citations

Antioxidant Function of the Mitochondrial Protein SP-22 in the Cardiovascular System

1999 • 132 citations

Characterization of the cysteinyl-containing peptides of the gamma subunit of coupling factor 1.

1984 • 119 citations

Inhibition of mitochondrial respiratory chain complex I by TNF results in cytochrome c release, membrane permeability transition, and apoptosis

1998 • 119 citations

Human transcription factor IIIC (TFIIIC)

1989 • 110 citations

Cloning of a housekeeping-type gene (MERS) preferentially expressed in murine erythroleukemia cells

1989 • 110 citations

Expression of novel antioxidant thioredoxin‐2 in the rat brain

2000 • 68 citations

Induction of mitochondrial manganese superoxide dismutase confers resistance to apoptosis in acute myeloblastic leukaemia cells exposed to etoposide

2000 • 64 citations

ATP depletion inhibits glucocorticoid-induced thymocyte apoptosis

1997 • 61 citations

cDNA sequence and predicted primary structure of the gamma subunit from the ATP synthase from Chlamydomonas reinhardtii.

1988 • 58 citations

The DNA Binding of Purified Ah Receptor Heterodimer Is Regulated by Redox Conditions

1995 • 43 citations

Factor B and the Mitochondrial ATP Synthase Complex

2002 • 38 citations

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