The uncharged surface features surrounding the active site ofEscherichia coliDsbA are conserved and are implicated in peptide binding

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1992 • 3,863 citations

Accurate bond and angle parameters for X-ray protein structure refinement

1991 • 2,467 citations

PROMOTIF—A program to identify and analyze structural motifs in proteins

1996 • 1,046 citations

Identification of a protein required for disulfide bond formation in vivo

1991 • 967 citations

Thioredoxin —a fold for all reasons

1995 • 799 citations

Expert system for predicting protein localization sites in gram‐negative bacteria

1991 • 739 citations

Protein disulphide isomerase: building bridges in protein folding

1994 • 718 citations

A pathway for disulfide bond formation in vivo.

1993 • 397 citations

Crystal structure of the DsbA protein required for disulphide bond formation in vivo

1993 • 387 citations

[11] Model building and refinement practice

1997 • 328 citations

An autoantibody to single‐stranded DNA: Comparison of the three‐dimensional structures of the unliganded fab and a deoxynucleotide–fab complex

1991 • 256 citations

Redox properties of protein disulfide isomerase (dsba) from escherichia coli

1993 • 242 citations

Identification and characterization of the Escherichia coli gene dsbB, whose product is involved in the formation of disulfide bonds in vivo.

1993 • 236 citations

Characterization of a periplasmic thiol:disulfide interchange protein required for the functional maturation of secreted virulence factors of Vibrio cholerae.

1992 • 228 citations

Building bridges: disulphide bond formation in the cell

1994 • 213 citations

Major antigen-induced domain rearrangements in an antibody

1993 • 206 citations

The Atomic Structure of Erythrocruorin in the Light of the Chemical Sequence and its Comparison with Myoglobin

1971 • 152 citations

The solution structure of human thioredoxin complexed with its target from Ref-1 reveals peptide chain reversal

1996 • 148 citations

Evidence that the pathway of disulfide bond formation in Escherichia coli involves interactions between the cysteines of DsbB and DsbA.

1995 • 135 citations

A homologue of the Escherichia coli DsbA protein involved in disulphide bond formation is required for enterotoxin biogenesis in Vibrio cholerae

1992 • 130 citations

Two cysteines in each periplasmic domain of the membrane protein DsbB are required for its function in protein disulfide bond formation.

1994 • 129 citations

Nucleotide sequence of a 13.9 kb segment of the 90 kb virulence plasmid of Salmonella typhimurium: the presence of fimbriai biosynthetic genes

1993 • 128 citations

Disulfide oxidoreductase activity of Shigella flexneri is required for release of Ipa proteins and invasion of epithelial cells.

1995 • 112 citations

In vivo control of redox potential during protein folding catalyzed by bacterial protein disulfide-isomerase (DsbA).

1993 • 109 citations

Catalytic Mechanism of DsbA and Its Comparison with That of Protein Disulfide Isomerase

1995 • 95 citations

Effects of DsbA on the Disulfide Folding of Bovine Pancreatic Trypsin Inhibitor and .alpha.-Lactalbumin

1994 • 92 citations

Ionization Equilibria for Side-Chain Carboxyl Groups in Oxidized and Reduced Human Thioredoxin and in the Complex with Its Target Peptide from the Transcription Factor NFκB

1996 • 87 citations

Bacterial protein disulfide isomerase: Efficient catalysis of oxidative protein folding at acidic pH

1993 • 86 citations

Proton Sharing between Cysteine Thiols in Escherichia coli Thioredoxin: Implications for the Mechanism of Protein Disulfide Reduction

1995 • 82 citations

A periplasmic protein disulfide oxidoreductase is required for transformation of Haemophilus influenzae Rd.

1992 • 73 citations

Structure of TcpG, the DsbA protein folding catalyst from Vibrio cholerae

1997 • 62 citations

Preferential binding of an unfolded protein to DsbA.

1996 • 56 citations

Differential effect of dsbA and dsbC mutations on extracellular enzyme secretion in Erwinia chrysanthemi

1995 • 54 citations

Direct Measurement of the Aspartic Acid 26 pK_a for Reduced Escherichia coli Thioredoxin by ¹³C NMR

1996 • 53 citations

Replacement of the Active-Site Cysteine Residues of DsbA, a Protein Required for Disulfide Bond Formation in vivo

1994 • 52 citations

Aspartic Acid 26 in Reduced Escherichia coli Thioredoxin Has a pKa >9

1995 • 46 citations

Crystallization of DsbA, an Escherichia coli Protein Required for Disulphide Bond Formation in Vivo

1993 • 43 citations

Cloning and expression of the gene for a protein disulfide oxidoreductase from Azotobacter vinelandii: complementation of an Escherichia coli dsbA mutant strain

1997 • 11 citations