Thiol modulation inhibits the interleukin (IL)‐1‐mediated activation of an IL‐1 receptor‐associated protein kinase and NF‐xB

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

1989 • 4,279 citations

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine).

1979 • 1,680 citations

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

1992 • 1,524 citations

Cytokine signal transduction

1994 • 1,358 citations

TRAF6 is a signal transducer for interleukin-1

1996 • 1,287 citations

cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily

1988 • 896 citations

IRAK: A Kinase Associated with the Interleukin-1 Receptor

1996 • 894 citations

Redox Regulation of NF-kappa B Activation

1997 • 852 citations

POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS

1972 • 742 citations

A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.

1991 • 677 citations

Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-α

1989 • 660 citations

Molecular Cloning and Characterization of a Second Subunit of the Interleukin 1 Receptor Complex

1995 • 634 citations

Interleukin 1 signaling occurs exclusively via the type I receptor.

1993 • 609 citations

The Dithiocarbamates and Related Compounds

1963 • 500 citations

Identification and quantitation of glutathione in hepatic protein mixed disulfides and its relationship to glutathione disulfide

1983 • 353 citations

[11] Diamide: An oxidant probe for thiols

1995 • 333 citations

The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo

1994 • 321 citations

The biological properties of interleukin-1.

1994 • 320 citations

Iron Acquired from Transferrin by K562 Cells Is Delivered into a Cytoplasmic Pool of Chelatable Iron(II)

1995 • 320 citations

Fatty Acid Substrate Specificities of Human Prostaglandin-endoperoxide H Synthase-1 and −2

1995 • 294 citations

Dithiocarbamates Induce Apoptosis in Thymocytes by Raising the Intracellular Level of Redox-active Copper

1995 • 280 citations

Distinct effects of glutathione disulphide on the nuclear transcription factors κB and the activator protein‐1

1994 • 274 citations

Formation and reduction of glutathione-protein mixed disulfides during oxidative stress

1987 • 267 citations

Redox control of enzyme activities by thiol/disulfide exchange

1984 • 264 citations

Tyrosine phosphorylation in T cells is regulated by phosphatase activity: studies with phenylarsine oxide.

1990 • 246 citations

Interleukin 1 signaling occurs exclusively via the typeI receptor

1993 • 228 citations

Interleukin 1 induces NF-kappa B through its type I but not its type II receptor in lymphocytes.

1992 • 212 citations

Structure of the human interleukin 2 gene.

1983 • 197 citations

Menadione-induced bleb formation in hepatocytes is associated with the oxidation of thiol groups in actin

1988 • 168 citations

Mixed Disulfides: Biological Functions and Increase in Oxidative Stress

1985 • 149 citations

The phosphatase activity of carbonic anhydrase III is reversibly regulated by glutathiolation.

1996 • 148 citations

Thiol modulation of TNF? and IL-1 induced MnSOD gene expression and activation of NF-?B

1995 • 128 citations

Macrophage Differentiation Marker MyD88 Is a Member of the Toll/IL-1 Receptor Family

1994 • 127 citations

Interleukin‐1‐induced activation of a protein kinase co‐precipitating with the type I interleukin‐1 receptor in T cells

1994 • 76 citations

Interaction between Tetraethylthiuram Disulfide and the Sulfhydryl Groups of d-Amino Acid Oxidase and of Hemoglobin

1966 • 71 citations

Inhibition of erythrocyte superoxide dismutase by diethyldithiocarbamate also results in oxyhemoglobin-catalyzed glutathione depletion and methemoglobin production.

1986 • 68 citations

Co‐expression of mRNA for type I and type II Interleukin‐1 receptors and the IL‐1 receptor accessory protein correlates to IL‐1 responsiveness

1996 • 53 citations

[44] Labeling of protein vicinal dithiols: Role of protein-S2 to protein-(SH)2 conversion in metabolic regulation and oxidative stress

1994 • 48 citations

[43] Purification of vicinal dithiol-containing proteins by arsenical-based affinity chromatography

1994 • 44 citations

Molecular Mechanisms of Nitrofurantoin-Induced Hepatocyte Toxicity in Aerobic versus Hypoxic Conditions

1993 • 36 citations

Type II interleukin-1 receptor is not expressed in cultured endothelial cells and is not involved in endothelial cell activation

1993 • 32 citations

A novel interaction of diethyldithiocarbamate with the glutathione/glutathione peroxidase system

1986 • 31 citations

Diethyldithiocarbamate (ditiocarb sodium) effect on arachidonic acid metabolism in human mononuclear cells

1992 • 24 citations

Studies on Se incorporation in selenoproteins; effects of peroxisome proliferators and hydrogen peroxide generating system

1992 • 18 citations

Sulfhydryl reactive phenylarsine oxide inhibits signal transduction in NK and LAK cells: Effect on zeta-chain phosphorylation and phosphatidylinositol level

1993 • 10 citations

Coexpression of type I and type II IL‐1 receptors in the murine T helper 2 cell line D10N

1993 • 8 citations

A BIOCHEMICAL MECHANISM FOR THE OXIDATION OF GLUTATHIONE BY XENOBIOTIC THIOLS

1989 • 2 citations