Toward a Molecular Understanding of Psychostimulant Actions Using Genetically Engineered Dopamine Receptor Knockout Mice as Model Systems

Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis

1986 • 2,110 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

Drugs of abuse: anatomy, pharmacology and function of reward pathways

1992 • 2,091 citations

Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity

1991 • 2,025 citations

Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis

1986 • 1,751 citations

Chemical Neuroanatomy

1984 • 1,646 citations

Dopamine (3-hydroxytyramine) and brain function.

1966 • 1,401 citations

A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants

1997 • 1,234 citations

Neuroscience of Addiction

1998 • 1,030 citations

The dopamine hypothesis of the reinforcing properties of cocaine

1991 • 990 citations

Recent Advances in the Molecular Biology of Dopamine Receptors

1993 • 768 citations

Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens

1980 • 736 citations

On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine

1977 • 733 citations

Mechanisms of Amphetamine Action Revealed in Mice Lacking the Dopamine Transporter

1998 • 622 citations

Effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens

1990 • 538 citations

Molecular Diversity of the Dopamine Receptors

1993 • 506 citations

Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals

1993 • 502 citations

Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses

1994 • 490 citations

A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice.

1996 • 473 citations

Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine.

1992 • 466 citations

Altered striatal function in a mutant mouse lacking D1A dopamine receptors.

1994 • 350 citations

Functions of dopamine in the dorsal and ventral striatum

1992 • 340 citations

Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant mice

1994 • 334 citations

Dopamine D3 Receptor Mutant Mice Exhibit Increased Behavioral Sensitivity to Concurrent Stimulation of D1 and D2 Receptors

1997 • 321 citations

D1 dopamine receptor activation is necessary for the induction of sensitization by amphetamine in the ventral tegmental area

1996 • 285 citations

Network-Level Changes in Expression of Inducible Fos–Jun Proteins in the Striatum during Chronic Cocaine Treatment and Withdrawal

1996 • 274 citations

Microinjection of cocaine into the nucleus accumbens elicits locomotor activation in the rat

1990 • 274 citations

Molecular Neurobiology of Dopaminergic Receptors

1993 • 251 citations

Alterations in Dopamine Release But Not Dopamine Autoreceptor Function in Dopamine D₃Receptor Mutant Mice

1998 • 239 citations

Addiction to Cocaine and Amphetamine

1996 • 234 citations

Dopamine uptake: A review of progress in the last decade

1990 • 231 citations

The persistence of behavioral sensitization to cocaine parallels enhanced inhibition of nucleus accumbens neurons

1995 • 222 citations

Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens.

1995 • 202 citations

Cellular responses to psychomotor stimulant and neuroleptic drugs are abnormal in mice lacking the D1 dopamine receptor

1996 • 191 citations

Repeated cocaine administration induces behavioral sensitization and corresponding decreased extracellular dopamine responses in caudate and accumbens

1992 • 181 citations

Dopamine, addiction and reward

1992 • 179 citations

An Escalating Dose “Binge” Model of Amphetamine Psychosis: Behavioral and Neurochemical Characteristics

1997 • 119 citations

Evidence for selective involvement of dopamine D1 receptors of the ventral tegmental area in the behavioral sensitization induced by intra-ventral tegmental area injections of D-amphetamine.

1996 • 108 citations

Dopamine D3 receptor mutant and wild-type mice exhibit identical responses to putative D3 receptor-selective agonists and antagonists

1999 • 97 citations

Repeated intra-ventral tegmental area administration of SKF-38393 induces behavioral and neurochemical sensitization to a subsequent cocaine challenge.

1996 • 81 citations

Electrophysiological Correlates of Psychomotor Stimulant‐induced Sensitizationa

1992 • 30 citations

Behavioral sensitization to stress and psychostimulants: Role of dopamine and excitatory amino acids in the mesocorticolimbic system

1993 • 23 citations

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