Dopamine uptake: A review of progress in the last decade

Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine

1987 • 2,189 citations

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity.

1985 • 1,253 citations

A family of receptors coupled to guanine nucleotide regulatory proteins

1987 • 636 citations

New concepts in cocaine addiction: The dopamine depletion hypothesis

1985 • 608 citations

Chemical release of dopamine from striatal homogenates: evidence for an exchange diffusion model.

1979 • 436 citations

Scope and limitations of in vivo brain dialysis: A comparison of its application to various neurotransmitter systems

1987 • 431 citations

Real-time characterization of dopamine overflow and uptake in the rat striatum

1988 • 420 citations

Dopamine can be released by two mechanisms differentially affected by the dopamine transport inhibitor nomifensine.

1979 • 382 citations

The dopamine uptake inhibitor GBR 12909: selectivity and molecular mechanism of action

1989 • 343 citations

Uptake of MPP(+) by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP

1984 • 313 citations

[3H]mazindol binding associated with neuronal dopamine and norepinephrine uptake sites.

1984 • 280 citations

Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes

1985 • 270 citations

Sodium‐Sensitive Cocaine Binding to Rat Striatal Membrane: Possible Relationship to Dopamine Uptake Sites

1983 • 258 citations

MPTP: current concepts and controversies.

1986 • 234 citations

Behavioral properties of GBR 12909, GBR 13069 and GBR 13098: Specific inhibitors of dopamine uptake

1984 • 233 citations

Biochemical and Pharmacological Characterization of [³H]GBR 12935 Binding In Vitro to Rat Striatal Membranes: Labeling of the Dopamine Uptake Complex

1987 • 231 citations

Extracellular dopamine in rat striatum following uptake inhibition by cocaine, nomifensine and benztropine

1987 • 226 citations

Effects of phencyclidine on [3H]catecholamine and [3H]serotonin uptake in synaptosomal preparations from rat brain

1977 • 214 citations

Purification and identification of the functional sodium- and chloride-coupled gamma-aminobutyric acid transport glycoprotein from rat brain.

1986 • 184 citations

Characterization of Sodium‐Dependent [³H]GBR‐12935 Binding in Brain: A Radioligand for Selective Labelling of the Dopamine Transport Complex

1986 • 171 citations

Sodium dependent [3H]cocaine binding associated with dopamine uptake sites in the rat striatum and human putamen decrease after dopaminergic denervation and in Parkinsons disease

1985 • 163 citations

.gamma.-Aminobutyric acid transport in reconstituted preparations from rat brain: coupled sodium and chloride fluxes

1988 • 163 citations

Pharmacological and neurochemical investigations of lead-induced hyperactivity

1975 • 161 citations

The effects of phencyclidine on the uptake of 3H-catecholamines by rat striatal and hypothalamic synaptosomes

1976 • 161 citations

ChemInform Abstract: ARYL 1,4‐DIALK(EN)YLPIPERAZINES AS SELECTIVE AND VERY POTENT INHIBITORS OF DOPAMINE UPTAKE

1981 • 150 citations

[3H]N-[1-(2-Benzo(b)thiophenyl) cycohexyl]piperidine ([3H]BTCP): a new phencyclidine analog selective for the dopamine uptake complex

1988 • 146 citations

In vivoevaluation of striatal dopamine reuptake sites using 11C-nomifensine and positron emission tomography

1987 • 146 citations

In vivo neurochemical profile of dopamine uptake inhibitors and releasers in rat caudate-putamen

1989 • 139 citations

Binding characteristics of the dopamine uptake inhibitor [3H]nomifensine to striatal membranes

1985 • 136 citations

Role of the dopamine uptake carrier in the neurochemical response to methamphetamine: Effects of amfonelic acid

1985 • 124 citations

Dopamine re-uptake inhibitors show inconsistent effects on the in vivo release of dopamine as measured by intracerebral dialysis in the rat

1987 • 123 citations

Striatal dopamine uptake in the rat: In vivo analysis by fast cyclic voltammetry

1984 • 121 citations

High Affinity Stereospecific Binding of [³H] Cocaine in Striatum and its Relationship to the Dopamine Transporter

1987 • 120 citations

Decreased density of human striatal dopamine uptake sites with age

1986 • 116 citations

Is there a functional linkage between neurotransmitter uptake mechanisms and presynaptic receptors?

1984 • 112 citations

High-affinity [3H]GBR 12783 binding to a specific site associated with the neuronal dopamine uptake complex in the central nervous system

1986 • 110 citations

Saturable (3H)cocaine binding in central nervous system of mouse

1980 • 108 citations

Uptake and efflux of ¹⁴ C‐dopamine in platelets

1975 • 107 citations

Lack of a high affinity transport system for dopamine in the median eminence and posterior pituitary

1979 • 106 citations

GBR 12783, a potent and selective inhibitor of dopamine uptake: Biochemical studies in vivo and ex vivo

1986 • 106 citations

Comparison of uptake of dopamine in rat striatal chopped tissue and synaptosomes.

1988 • 103 citations

[3H]GBR-12935: A specific high affinity ligand for labeling the dopamine transport complex

1985 • 100 citations

[3H]mazindol binding associated with neuronal dopamine uptake sites in corpus striatum membranes

1983 • 99 citations

Ca2+ dependence of the amphetamine, nomifensine, and Lu 19-005 effect on in vivo dopamine transmission

1989 • 96 citations

Citalopram antagonizes the stimulation by lysergic acid diethylamide of presynaptic inhibitory serotonin autoreceptors in the rat hypothalamus.

1982 • 95 citations

Properties of the optical isomers and metabolites of ketamine on the high affinity transport and catabolism of monoamines

1981 • 92 citations

[³H]GBR‐12935 Binding to the Dopamine Transporter Is Decreased in the Caudate Nucleus in Parkinson's Disease

1987 • 91 citations

The central stimulatory action of inhibitors of the dopamine uptake

1979 • 90 citations

Neurochemical Profile of Lu 19‐005, a Potent Inhibitor of Uptake of Dopamine, Noradrenaline, and Serotonin

1985 • 89 citations

THE UPTAKE AND RELEASE OF [³H]DOPAMINE IN THE GOLDFISH RETINA

1979 • 88 citations

Monoamine re-uptake sites in the human brain evaluatedin vivoby means of¹¹C-nomifensine and positron emission tomography: the effects of age and Parkinson's disease

1988 • 88 citations

[3H]GBR 12935 binding to dopamine uptake sites: subcellular localizatio and reduction in Parkinson's disease and progressive supranuclear palsy

1988 • 87 citations

Interactions of lead and calcium on the synaptosomal uptake of dopamine and choline

1977 • 86 citations

Diffusion and uptake of dopamine in rat caudate and nucleus accumbens compared using fast cyclic voltammetry

1988 • 82 citations

Role of the aromatic group in the inhibition of phencyclidine binding and dopamine uptake by PCP analogs

1989 • 81 citations

The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine (mptp) and its relevance to parkinson's disease

1987 • 74 citations

Cocaine self-administration appears to be mediated by dopamine uptake inhibition

1988 • 74 citations

Inhibition of [3H]dopamine accumulation in rat striatal synaptosomes by psychotropic drugs

1978 • 72 citations

Differences in the Kinetics of Dopamine Uptake in Synaptosome Preparations of the Median Eminence Relative to Other Dopaminergically Inervated Brain Regions

1980 • 71 citations

Dopamine but not norepinephrine or serotonin uptake inhibitors protect mice against neurotoxicity of MPTP

1985 • 70 citations

The Mechanism of neuronal and extraneuronal transport of catecholamines

1976 • 69 citations

Dopamine-Accumulating Retinal Neurons Revealed by in Vitro Fluorescence Display a Unique Morphology

1988 • 69 citations

Dopamine transport sites selectively labeled by a novel photoaffinity probe: 125I-DEEP

1989 • 68 citations

[3H]GBR-12935 binding to dopamine uptake sites in the human brain

1988 • 66 citations

The effects of surgical and chemical lesions on striatal binding: Correlation with [3H]dopamine uptake

1985 • 64 citations

Chronic L-deprenyl-induced up-regulation of the dopamine uptake carrier

1989 • 59 citations

Studies in postmortem dopamine uptake

1987 • 58 citations

PLASMA UPTAKE OF DOPAMINE AND 5-HYDROXYTRYPTAMINE AND PLASMA-CATECHOLAMINE LEVELS IN PATIENTS WITH HUNTINGTON'S CHOREA

1974 • 58 citations

The Differential Effect of Ischemia on the Active Uptake of Dopamine, γ‐Aminobutyric Acid, and Glutamate by Brain Synap to somes

1982 • 56 citations

Inhibition of synaptosomal high-affinity uptake of dopamine and serotonin by estrogen agonists and antagonists

1987 • 55 citations

Presynaptic inhibition by dopamine receptor agonists of noradrenergic neurotransmission in the rabbit hypothalamus.

1982 • 55 citations

In vivo voltammetric characterization of low affinity striatal dopamine uptake: Drug inhibition profile and relation to dopaminergic innervation density

1986 • 54 citations

A peptide-containing fraction in the urine of schizophrenic patients which stimulates opiate receptors and inhibits dopamine uptake

1979 • 51 citations

Frequency-dependent effects of neuronal uptake inhibitors on the autoreceptor-mediated modulation of dopamine and acetylcholine release from the rabbit striatum.

1983 • 48 citations

Coexistence of carriers for dopamine and GABA uptake on a same nerve terminal in the rat brain

1987 • 47 citations

Striatal dopamine uptake and swim performance of the aged rat

1986 • 46 citations

A common uptake system for serotonin and dopamine in human platelets.

1978 • 46 citations

Tetrahydro‐β‐carbolines and Corresponding Tryptamines: In Vitro Inhibition of Serotonin, Dopamine and Noradrenaline Uptake in Rat Brain Synaptosomes

1980 • 45 citations

Dopamine uptake inhibitors and releasing agents differentiated by the use of synaptosomes and field-stimulated brain slices in vitro

1979 • 44 citations

Effects of cocaine on release and uptake of dopamine in vivo: Differentiation by mathematical modeling

1988 • 43 citations

Characteristics of [3H](+)-amphetamine binding sites in the rat central nervous system

1984 • 41 citations

Relationship between transmitter uptake inhibition and effects of ?-adrenoceptor agonists on serotonin and noradrenaline release in the rat brain cortex

1983 • 41 citations

Uptake and release of [3H]dopamine by the median eminence: Evidence for presynaptic dopaminergic receptors and for dopaminergic feedback inhibition

1983 • 41 citations

Uptake and release of [3H]dopamine and dopamine-sensitive adenylate cyclase activity in retinal synaptosomal fractions

1978 • 40 citations

Synthesis and pharmacological evaluation of some new tetrahydroisoquinoline derivatives inhibiting dopamine uptake and/or possessing a dopaminomimetic property

1986 • 40 citations

Effect of Heavy Metals on Dopamine, Noradrenaline and Serotonin Uptake and Release in Rat Brain Synaptosomes

1981 • 39 citations

Involvement of sialic acid in high-affinity uptake of dopamine by synaptosomes from rat brain

1987 • 38 citations

Quantitative autoradiographic localization of the dopamine transport complex in the rat brain: use of a highly selective radioligand: [3H]GBR 12935

1986 • 37 citations

Simultaneous evaluation by a double labelling method of drug-induced uptake inhibition and release of dopamine in synaptosomal preparation of rat striatum

1984 • 36 citations

Uptake of Taurine, GAB A, 5‐HT, and Dopamine by Blood Platelets in Progressive Myoclonus Epilepsy

1979 • 35 citations

Developmental studies of the uptake of choline, gaba and dopamine by crude synaptosomal preparations after in vivo or in vitro lead treatment

1980 • 35 citations

Characterization of high affinity dopamine uptake into the dopamine neurons of the hypothalamus

1982 • 35 citations

The human platelet as a model for the dopaminergic neuron: Kinetic and pharmacologic properties and the role of amine storage granules

1978 • 33 citations

Studies in postmortem dopamine uptake

1987 • 33 citations

The regional distribution of dopamine and serotonin uptake and transmitter concentrations in the human brain

1987 • 33 citations

MPTP Toxicity in Relation to Age, Dopamine Uptake and MAO‐B Activity in Two Rodent Species

1989 • 32 citations

Tetrahydro‐β‐carbolines and Corresponding Tryptamines: In Vitro Inhibition of Serotonin and Dopamine Uptake by Human Blood Platelets

1980 • 31 citations

In vivo binding of [3H]GBR 12783, a selective dopamine uptake inhibitor, in mouse striatum

1987 • 31 citations

Pharmacological studies with several analogs of mazindol: Correlation between effects on dopamine uptake and various in vivo responses

1981 • 31 citations

Interactions of amineptine with the neuronal dopamine uptake system: Neurochemicalin vitro andin vivo studies

1987 • 29 citations

Dopamine uptake in platelets: Two different low-affinity, saturable mechanisms

1981 • 28 citations

Influence of Hypoxia on Release and Uptake of Neurotransmitters in Guinea Pig Striatal Slices: Dopamine and Acetylcholine

1985 • 28 citations

Dopamine Uptake by Rat Striatal Synaptosomes: Time‐and Temperature‐Dependent Decay and Protection by Dithiothreitol and Dopamine

1983 • 28 citations

The influence of cholesterol on synaptic fluidity and dopamine uptake

1989 • 27 citations

Monoamine uptake into synaptosomes from various regions of rat brain following lithium administration and withdrawal

1981 • 27 citations

Dopamine Uptake by Rat Striatal Synaptosomes: A Compartmental Analysis

1983 • 27 citations

Effects of Polyamines on the Uptake of Neurotransmitters by Rat Brain Synaptosomes

1984 • 27 citations

Phencyclidine: Effect on the accumulation of 3H-dopamine in synaptic vesicles

1980 • 26 citations

Characteristics of dopamine and GABA transport in primary cultures of astroglial cells

1984 • 25 citations

Differential effects of several dopamine uptake inhibitors and releasing agents on locomotor activity in normal and in reserpinized mice

1981 • 25 citations

Uptake of [3H]dopamine in periglomerular cells of the rat olfactory bulb: an autoradiographic study

1979 • 24 citations

Effects of local anesthetics on phospholipid topology and dopamine uptake and release in rat brain synaptosomes

1982 • 21 citations

Interactions between endogenous dopamine and dopamine agonists at release modulatory receptors: multiple effects of neuronal uptake inhibitors on transmitter release.

1986 • 21 citations

Chronic Manganese Treatment of Rats Alters Synaptosomal Uptake of Dopamine and the Behavioural Response to Amphetamine Administration

1982 • 20 citations

In vivo labelling of the mouse dopamine uptake complex with the phencyclidine derivative [3H]BTCP

1989 • 20 citations

Motor activity and rotational behavior after analogs of cocaine: correlation with dopamine uptake blockade.

1979 • 19 citations

Dopamine uptake during fast-phase endogenous dopamine release from mouse striatal synaptosomes

1986 • 19 citations

Localization of the dopamine uptake complex using [3H]N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine ([3H]BTCP) in rat brain

1989 • 19 citations

Effects of dopamine uptake inhibitors on schedule-controlled behavior in the squirrel monkey

1982 • 19 citations

Antihistamine effect on synaptosomal uptake of serotonin, norepinephrine and dopamine

1980 • 19 citations

The effect of dopamine uptake blocking agents on the amphetamine-induced circling behavior in mice with unilateral nigro-striatal lesions.

1980 • 18 citations

Differences in the inhibitory effect of Cd2+, Mn2+ and Al3+ on the uptake of dopamine by synaptosomes from forebrain and from striatum of the rat

1981 • 18 citations

Increase in Dopamine Uptake in Rat Striatal Synaptosomes after an Acute in Vivo Administration of Organic and Inorganic Lead

1983 • 17 citations

Dopamine transporter: Solubilization from dog caudate nucleus

1989 • 15 citations

In vivo and in vitro autoradiographic labelling of central dopaminergic systems with [3H]GBR12783 in rodents

1988 • 15 citations

The accumulation of dopamine into striatal synaptosomes, and its inhibition: comparison of crude, partially purified and purified synaptosomal preparations.

1979 • 15 citations

Mesocortical vs nigrostriatal dopamine uptake in isolated fighting mice

1981 • 15 citations

In vivo studies on the dopamine re-uptake mechanism in the striatum of the rat: Effects of benztropine, sodium and ouabain

1988 • 15 citations

Sodium independence of the binding of [3H]GBR 12783 and other dopamine uptake inhibitors to the dopamine uptake complex

1987 • 13 citations

Synaptosomal Uptake and Release of Dopamine in Rat Striatum After Hypoxia

1987 • 13 citations

The effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on presynaptic dopamine uptake sites in the mouse striatum

1986 • 12 citations

Long‐term blockade of the dopamine uptake complex by metaphit, an isothiocyanate derivative of phencyclidine

1989 • 12 citations

Inhibition of Synaptosomal Neurotransmitter Uptake by Hallucinogens

1983 • 12 citations

Studies on the stability of 3H-dopamine in neostriatal membrane preparations: Effects of ascorbic acid

1983 • 11 citations

Artefactual inhibition of dopamine uptake by psychotropic drugs on striatal synaptosomal preparation

1984 • 10 citations

Rapid determination of dopamine uptake in synaptosomal preparations

1983 • 10 citations

Effects of selective monoaminergic reuptake blockade on activity rhythms in developing rats

1989 • 10 citations

Inhibition of (3H)-dopamine uptake into rat brain synaptosomes by the new non-tricyclic antidepressants, FS32 and FS97

1980 • 10 citations

ONTOGENESIS OF UPTAKE AND DEAMINATION OF 5‐HYDROXYTRYPTAMINE, DOPAMINE AND β‐PHENYLETHYLAMINE IN ISOLATED PERFUSED LUNG AND LUNG HOMOGENATES FROM RATS

1981 • 9 citations

Dopamine reuptake inhibitors and dopamine releasers: Differential effect on plasma prolactin in the rat

1982 • 9 citations

Detection of neuronal uptake of [3H]dopamine in the rabbit celiac artery

1983 • 8 citations

Lability in storage of 3H-dopamine and 3H-norepinephrine in crude synaptosome (P2) and vesicle-associated fractions of rat brain

1984 • 8 citations

Time course of postmortem modifications in synaptosomal [3H]dopamine uptake and [3H]GBR 12783 binding to the dopamine uptake complex in the rat striatum

1989 • 7 citations

Platelet dopamine uptake in autistic and other psychotic children. Inhibition by imipramine

1980 • 6 citations

Synthetic analgesics and other phenylpiperidines: effects on uptake and storage of dopamine and other monoamines mouse forebrain tissue

1986 • 6 citations

Characterization of synaptosomal dopamine uptake in post-mortem brain regions of schizophrenics

1987 • 5 citations

Acute Effects of Nomifensine on in Vivo Uptake and Metabolism of Dopamine, Noradrenaline and Serotonin in the Rat Brain

1987 • 5 citations

Synaptosomal uptake and release of dopamine and 5-hydroxy-tryptamine in the nucleus accumbens in vitro following in vivo administration of lysergic acid diethylamide in rats.

1980 • 5 citations

Potentiation of morphine-elicited circling by dopaminergic uptake blockade

1988 • 4 citations

Conformationally rigid dopamine analogues as inhibitors of dopamine and 5-hydroxytryptamine uptake by synaptosomes

1987 • 4 citations

Dopamine Uptake Capacity of Platelets From People At Risk For Huntington’s Chorea

1981 • 3 citations

Similarities Between A.P.U.D. Cells and Monoaminergic Neurons: Evidence for a Dopamine Uptake Mechanism in C Cells of Chicken Ultimobranchial Gland

1980 • 3 citations

Effects of phenylethanolamine N-methyltransferase inhibitors on uptake and release of norepinephrine and dopamine from rat brain.

1985 • 2 citations

Effects of the optical isomers of 2-amino-3-fluoro-1-phenylpropane (monofluoroamphetamine) hydrochloride on uptake and release of dopamine in rat striatum in vitro

1981 • 2 citations

Failure of branched-chain amino acids to affect synaptosomal uptake of norepinephrine and dopamine.

1985 • 1 citations

Dopamine and 5-HT uptake by synaptosomes after pretreatment with p-chlorophenylalanine.

1983 • 1 citations

Effect of molecular size on inhibition of synaptosome dopamine uptake by antihistaminic pheniramines.

1982 • 1 citations