Reaction mechanism determines NMDA receptor response to repetitive stimulation

Magnesium gates glutamate-activated channels in mouse central neurones

1984 • 3,999 citations

NMDA receptor subunits: diversity, development and disease

2001 • 1,677 citations

Binding, gating, affinity and efficacy: The interpretation of structure‐activity relationships for agonists and of the effects of mutating receptors

1998 • 880 citations

Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons

1987 • 852 citations

Activity-Dependent Decrease in NMDA Receptor Responses During Development of the Visual Cortex

1992 • 731 citations

Functional and Pharmacological Differences Between RecombinantN-Methyl-<scp>d</scp>-Aspartate Receptors

1998 • 662 citations

Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors

1990 • 649 citations

Transmitter timecourse in the synaptic cleft: its role in central synaptic function

1996 • 599 citations

Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons

1990 • 553 citations

Selective Induction of LTP and LTD by Postsynaptic [Ca²⁺]_i Elevation

1999 • 512 citations

Transporters Buffer Synaptically Released Glutamate on a Submillisecond Time Scale

1997 • 471 citations

Facilitation at single synapses probed with optical quantal analysis

2002 • 330 citations

Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated

1999 • 321 citations

Maximum likelihood estimation of aggregated Markov processes

1997 • 273 citations

Restoration of Single-Channel Currents Using the Segmental k-Means Method Based on Hidden Markov Modeling

2004 • 243 citations

A Direct Optimization Approach to Hidden Markov Modeling for Single Channel Kinetics

2000 • 229 citations

Nonsaturation of AMPA and NMDA receptors at hippocampal synapses

2000 • 219 citations

Activation of AMPA, Kainate, and Metabotropic Receptors at Hippocampal Mossy Fiber Synapses

1998 • 200 citations

Identification of Amino Acid Residues of the NR2A Subunit That Control Glutamate Potency in Recombinant NR1/NR2A NMDA Receptors

1998 • 199 citations

A Single Packet of Transmitter Does Not Saturate Postsynaptic Glutamate Receptors

2002 • 180 citations

Burst kinetics of single calcium‐activated potassium channels in cultured rat muscle.

1983 • 174 citations

Modal gating of NMDA receptors and the shape of their synaptic response

2003 • 172 citations

A Monte Carlo Model Reveals Independent Signaling at Central Glutamatergic Synapses

2002 • 169 citations

Saturation of postsynaptic receptors at central synapses?

1996 • 109 citations

Subunit Interactions and AMPA Receptor Desensitization

2001 • 99 citations

The NMDA Receptor Gating Machine: Lessons from Single Channels

2004 • 39 citations

Changes in Agonist Concentration Dependence That Are a Function of Duration of Exposure SuggestN-Methyl-d-aspartate Receptor Nonsaturation during Synaptic Stimulation

2001 • 36 citations

Single‐channel analysis of an NMDA receptor possessing a mutation in the region of the glutamate binding site

2000 • 32 citations

Modal gating of NMDA receptors

2004 • 23 citations