The NMDA Receptor Gating Machine: Lessons from Single Channels

Glutamate receptor ion channels

2005 • 3,667 citations

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1994 • 3,437 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

Ion Channels/Excitable Membranes

2006 • 2,013 citations

NMDA receptor subunits: diversity, development and disease

2001 • 1,677 citations

Requirement for Glycine in Activation of NMDA-Receptors Expressed in Xenopus Oocytes

1988 • 1,415 citations

Cloning and characterization of chi-1: a developmentally regulated member of a novel class of the ionotropic glutamate receptor family

1995 • 1,252 citations

The Time Course of Glutamate in the Synaptic Cleft

1992 • 1,071 citations

Mice with Reduced NMDA Receptor Expression Display Behaviors Related to Schizophrenia

1999 • 1,063 citations

N-methyl-D-aspartic acid receptor structure and function

1994 • 989 citations

The Tetrameric Structure of a Glutamate Receptor Channel

1998 • 790 citations

NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampus

1989 • 654 citations

Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors

1990 • 649 citations

The Role of N-Methyl-d-Aspartate (NMDA) Receptors in Pain: A Review

2003 • 640 citations

Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A

1998 • 595 citations

Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents

1990 • 570 citations

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

1994 • 496 citations

NMDA channel behavior depends on agonist affinity

1992 • 401 citations

Dual‐component amino‐acid‐mediated synaptic potentials: excitatory drive for swimming in Xenopus embryos.

1985 • 334 citations

Excitation of mammalian central neurones by acidic amino acids

1972 • 239 citations

Activation of NR1/NR2B NMDA receptors

2003 • 210 citations

Motor Discoordination Results from Combined Gene Disruption of the NMDA Receptor NR2A and NR2C Subunits, But Not from Single Disruption of the NR2A or NR2C Subunit

1996 • 189 citations

Single glutamate-activated channels in locust muscle

1979 • 182 citations

Modal gating of NMDA receptors and the shape of their synaptic response

2003 • 172 citations

High Probability Opening of NMDA Receptor Channels by L-Glutamate

1992 • 166 citations

Mechanisms of Activation of Glutamate Receptors and the Time Course of Excitatory Synaptic Currents

1995 • 157 citations

Excitatory amino acid receptors expressed in Xenopus oocytes: agonist pharmacology.

1988 • 146 citations

Modification of NMDA Receptor Channels and Synaptic Transmission by Targeted Disruption of the NR2C Gene

1996 • 139 citations

Constraining Ligand-Binding Site Stoichiometry Suggests that a Cyclic Nucleotide–Gated Channel Is Composed of Two Functional Dimers

1998 • 136 citations

Glycine-insensitive desensitization of NMDA responses in cultured mouse embryonic neurons

1990 • 109 citations

The NMDA Receptor Channel: Molecular Design of a Coincidence Detector

1995 • 101 citations

Glutamate activation of a single NMDA receptorchannel produces a cluster of channel openings

1991 • 99 citations

Cell surface expression of the human N-methyl-d-aspartate receptor subunit 1a requires the co-expression of the NR2A subunit in transfected cells

1996 • 94 citations

The role of mammalian ionotropic receptors in synaptic plasticity: LTP, LTD and epilepsy

2000 • 88 citations

On the kinetics of large-conductance glutamate-receptor ion channels in rat cerebellar granule neurons

1988 • 72 citations

Calcium-dependent, slow desensitization distinguishes different types of glutamate receptors

1989 • 63 citations

Desensitization of NMDA Receptor Channels Is Modulated by Glutamate Agonists

2001 • 61 citations

Mice with Genetically Modified NMDA and AMPA Receptors

1999 • 35 citations

Modal gating of NMDA receptors

2004 • 23 citations