Activation-modulated Association of 14–3–3 Proteins with Cbl in T Cells

Signal transduction by lymphocyte antigen receptors

1994 • 2,145 citations

SH2 and SH3 domains: From structure to function

1992 • 977 citations

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

1994 • 886 citations

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

1985 • 813 citations

Crystal structure of the zeta isoform of the 14-3-3 protein

1995 • 516 citations

Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways

1995 • 473 citations

Binding of 14-3-3 Proteins to the Protein Kinase Raf and Effects on Its Activation

1994 • 415 citations

Activation of Raf-1 by 14-3-3 proteins

1994 • 370 citations

Signalling through SH2 and SH3 domains

1993 • 355 citations

v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas.

1989 • 316 citations

The protein product of the c-cbl protooncogene is the 120-kDa tyrosine-phosphorylated protein in Jurkat cells activated via the T cell antigen receptor.

1994 • 299 citations

Stimulatory Effects of Yeast and Mammalian 14-3-3 Proteins on the Raf Protein Kinase

1994 • 299 citations

Similarity of sli-1 , a Regulator of Vulval Development in C. elegans , to the Mammalian Proto-Oncogene c- cbl

1995 • 298 citations

Interaction of the Protein Kinase Raf-1 with 14-3-3 Proteins

1994 • 285 citations

14-3-3 proteins on the MAP

1995 • 255 citations

Isoforms of 14‐3‐3 protein can form homo‐ and heterodimers in vivo and in vitro: implications for function as adapter proteins

1995 • 254 citations

14-3-3 proteins associate with cdc25 phosphatases.

1995 • 251 citations

Association of the Protein Kinases c-Bcr and Bcr-Abl with Proteins of the 14-3-3 Family

1994 • 233 citations

Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation.

1995 • 231 citations

Interactions of Cbl with Grb2 and Phosphatidylinositol 3′-Kinase in Activated Jurkat Cells

1995 • 217 citations

14-3-3 Is Not Essential for Raf-1 Function: Identification of Raf-1 Proteins That Are Biologically Activated in a 14-3-3- and Ras-Independent Manner

1995 • 217 citations

14-3-3: Modulators of Signaling Proteins?

1994 • 206 citations

Tyrosine Phosphorylation of the c-cbl Proto-oncogene Protein Product and Association with Epidermal Growth Factor (EGF) Receptor upon EGF Stimulation

1995 • 202 citations

Bcr and Raf form a complex in vivo via 14-3-3 proteins.

1995 • 201 citations

The Proto-oncogene Product c-Cbl Becomes Tyrosine Phosphorylated by Stimulation with GM-CSF or Epo and Constitutively Binds to the SH3 Domain of Grb2/Ash in Human Hematopoietic Cells

1995 • 179 citations

Association of Polyomavirus Middle Tumor Antigen with 14-3-3 Proteins

1994 • 162 citations

Physical association between Src homology 3 elements and the protein product of the c-cbl proto-oncogene

1994 • 148 citations

Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells.

1995 • 139 citations

The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase.

1995 • 131 citations

Expression and Structural Analysis of 14-3-3 Proteins

1995 • 127 citations

The truncation that generated the v-cbl oncogene reveals an ability for nuclear transport, DNA binding and acute transformation.

1993 • 109 citations

Demonstration of the Phosphorylation-Dependent Interaction of Tryptophan Hydroxylase with the 14-3-3 Protein

1993 • 103 citations

T cell antigen receptor signaling: Three families of tyrosine kinases and a phosphatase

1994 • 92 citations

14-3-3 Proteins: Hot numbers in signal transduction

1995 • 82 citations

Characterization of 14-3-3 proteins in adrenal chromaffin cells and demonstration of isoform-specific phospholipid binding

1994 • 60 citations

Processing of a fusion protein by endoprotease in COS-1 cells for secretion of mature peptide by using a chimeric expression vector.

1993 • 46 citations

Requirement of posttranslational modifications for the generation of biologic activity of glycosylation-inhibiting factor.

1994 • 26 citations