TRBP, a regulator of cellular PKR and HIV‐1 virus expression, interacts with Dicer and functions in RNA silencing

MicroRNA biogenesis: coordinated cropping and dicing

2005 • 2,443 citations

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

2005 • 2,046 citations

Dicer is essential for mouse development

2003 • 1,896 citations

Perspective: machines for RNAi

2005 • 942 citations

RNAi-mediated pathways in the nucleus

2005 • 839 citations

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

2003 • 690 citations

A Protein Sensor for siRNA Asymmetry

2004 • 584 citations

Normal microRNA Maturation and Germ-Line Stem Cell Maintenance Requires Loquacious, a Double-Stranded RNA-Binding Domain Protein

2005 • 537 citations

Evidence that HIV-1 Encodes an siRNA and a Suppressor of RNA Silencing

2005 • 428 citations

Processing of Pre-microRNAs by the Dicer-1–Loquacious Complex in Drosophila Cells

2005 • 421 citations

Characterization of a Human TAR RNA-Binding Protein That Activates the HIV-1 LTR

1991 • 391 citations

The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage

2005 • 273 citations

Functional Genomic Analysis of RNA Interference in C. elegans

2005 • 268 citations

Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR

1997 • 223 citations

Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer

2004 • 216 citations

A double-stranded RNA binding protein required for activation of repressed messages in mammalian germ cells

1999 • 162 citations

A Link Between RNA Interference and Nonsense-Mediated Decay in Caenorhabditis elegans

2000 • 145 citations

Two Dimerization Domains in the Trans-activation Response RNA-binding Protein (TRBP) Individually Reverse the Protein Kinase R Inhibition of HIV-1 Long Terminal Repeat Expression

2001 • 104 citations

The TAR RNA-binding Protein, TRBP, Stimulates the Expression of TAR-containing RNAs in Vitro and in VivoIndependently of Its Ability to Inhibit the dsRNA-dependent Kinase PKR

2003 • 93 citations

Merlin, a Tumor Suppressor, Interacts with Transactivation-responsive RNA-binding Protein and Inhibits Its Oncogenic Activity

2004 • 64 citations

The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity

2003 • 60 citations

Serine 18 Phosphorylation of RAX, the PKR Activator, Is Required for PKR Activation and Consequent Translation Inhibition

2004 • 60 citations

Oligomerization activity of a double‐stranded RNA‐binding domain

2004 • 41 citations

Organization of the Human tarbp2 Gene Reveals Two Promoters That Are Repressed in an Astrocytic Cell Line

2001 • 36 citations