A Protein Sensor for siRNA Asymmetry

RNA interference is mediated by 21- and 22-nucleotide RNAs

2001 • 3,271 citations

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

2000 • 2,945 citations

Asymmetry in the Assembly of the RNAi Enzyme Complex

2003 • 2,761 citations

RNAi

2000 • 2,596 citations

Functional siRNAs and miRNAs Exhibit Strand Bias

2003 • 2,516 citations

Argonaute2, a Link Between Genetic and Biochemical Analyses of RNAi

2001 • 1,492 citations

Distinct Roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA Silencing Pathways

2004 • 1,254 citations

ATP Requirements and Small Interfering RNA Structure in the RNA Interference Pathway

2001 • 1,008 citations

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

2004 • 831 citations

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

2003 • 690 citations

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

2004 • 623 citations

Kinetic analysis of the RNAi enzyme complex

2004 • 537 citations

Evidence that siRNAs Function as Guides, Not Primers, in the Drosophila and Human RNAi Pathways

2002 • 473 citations

A Dicer-2-Dependent 80S Complex Cleaves Targeted mRNAs during RNAi in Drosophila

2004 • 417 citations

RISC is a 5′ phosphomonoester-producing RNA endonuclease

2004 • 409 citations

RNAi in Human Cells

2002 • 391 citations

RISC Assembly Defects in the Drosophila RNAi Mutant armitage

2004 • 377 citations

Identification of Modulators of TRAIL-Induced Apoptosis via RNAi-Based Phenotypic Screening

2003 • 343 citations

APC/C and SCF: Controlling Each Other and the Cell Cycle

2004 • 306 citations

The RNA-Induced Silencing Complex Is a Mg2+-Dependent Endonuclease

2004 • 261 citations

Short-Interfering-RNA-Mediated Gene Silencing in Mammalian Cells Requires Dicer and eIF2C Translation Initiation Factors

2003 • 224 citations

Short 5′-phosphorylated double-stranded RNAs induce RNA interference in Drosophila

2001 • 104 citations