Resistance to Neutralizing Antibody and Expanded Coreceptor Usage Are Associated with Human Immunodeficiency Virus Type 1 Isolates Derived from Chimpanzees with Pathogenic Infections

The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

1996 • 2,326 citations

CHEMOKINE RECEPTORS AS HIV-1 CORECEPTORS: Roles in Viral Entry, Tropism, and Disease

1999 • 2,174 citations

Change in Coreceptor Use Correlates with Disease Progression in HIV-1–Infected Individuals

1997 • 1,373 citations

In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression

1997 • 642 citations

Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein.

1989 • 628 citations

Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160

1990 • 593 citations

Neutralizing antibody directed against the HIV–1 envelope glycoprotein can completely block HIV–1/SIV chimeric virus infections of macaque monkeys

1999 • 547 citations

The V3 domain of the HIV–1 gp120 envelope glycoprotein is critical for chemokine–mediated blockade of infection

1996 • 499 citations

Prevention of HIV-1 infection in chimpanzees by gpl20 V3 domain-specific monoclonal antibody

1992 • 481 citations

Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120

1995 • 405 citations

Primary Human Immunodeficiency Virus Type 2 (HIV-2) Isolates, Like HIV-1 Isolates, Frequently Use CCR5 but Show Promiscuity in Coreceptor Usage

1999 • 326 citations

Cryptic nature of envelope V3 region epitopes protects primary monocytotropic human immunodeficiency virus type 1 from antibody neutralization

1994 • 241 citations

Inter- and intraclade neutralization of human immunodeficiency virus type 1: genetic clades do not correspond to neutralization serotypes but partially correspond to gp120 antigenic serotypes

1996 • 222 citations

Development of the anti-gp120 antibody response during seroconversion to human immunodeficiency virus type 1

1994 • 219 citations

Development of AIDS in a chimpanzee infected with human immunodeficiency virus type 1

1997 • 206 citations

Chemokine Coreceptor Usage by Diverse Primary Isolates of Human Immunodeficiency Virus Type 1

1998 • 139 citations

Differential Role of V3-Specific Antibodies in Neutralization Assays Involving Primary and Laboratory-Adapted Isolates of HIV Type 1

1995 • 118 citations

Vaccine-induced protection of chimpanzees against infection by a heterologous human immunodeficiency virus type 1

1995 • 97 citations

A chimpanzee-passaged human immunodeficiency virus isolate is cytopathic for chimpanzee cells but does not induce disease

1991 • 79 citations

Evidence that Antibody-Mediated Neutralization of Human Immunodeficiency Virus Type 1 by Sera from Infected Individuals Is Independent of Coreceptor Usage

1998 • 75 citations

Reversal of Human Immunodeficiency Virus Type 1 IIIB to a Neutralization-Resistant Phenotype in an Accidentally Infected Laboratory Worker with a Progressive Clinical Course

2001 • 75 citations

Progressive Infection in a Subset of HIV‐1–Positive Chimpanzees

2000 • 74 citations

Apoptosis of CD4+and CD19+Cells during Human Immunodeficiency Virus Type 1 Infection—Correlation with Clinical Progression, Viral Load, and Loss of Humoral Immunity

1997 • 71 citations

Study of the V3 Loop as a Target Epitope for Antibodies Involved in the Neutralization of Primary Isolates versus T-Cell-Line-Adapted Strains of Human Immunodeficiency Virus Type 1

1998 • 69 citations

Coreceptor usage of BOB/GPR15 and Bonzo/STRL33 by primary isolates of human immunodeficiency virus type 1.

1999 • 65 citations

Vaccine Protection against a Heterologous, Non-Syncytium-Inducing, Primary Human Immunodeficiency Virus

1998 • 63 citations

Simian Immunodeficiency Viruses of Diverse Origin Can Use CXCR4 as a Coreceptor for Entry into Human Cells

2000 • 62 citations

Loss of CD4⁺T Cells in Human Immunodeficiency Virus Type 1-Infected Chimpanzees Is Associated with Increased Lymphocyte Apoptosis

1998 • 61 citations

Antibody-mediated neutralization of primary isolates of human immunodeficiency virus type 1 in peripheral blood mononuclear cells is not affected by the initial activation state of the cells

1997 • 50 citations

The moving target: mechanisms of HIV persistence during primary infection

1999 • 50 citations

Rapid CD4⁺T-Cell Loss Induced by Human Immunodeficiency Virus Type 1_NCin Uninfected and Previously Infected Chimpanzees

2001 • 48 citations

Extensive Diversification of Human Immunodeficiency Virus Type 1 Subtype B Strains during Dual Infection of a Chimpanzee That Progressed to AIDS

1998 • 46 citations

Molecular Cloning and Characterization of Viruses Isolated from Chimpanzees with Pathogenic Human Immunodeficiency Virus Type 1 Infections

1998 • 41 citations

Chemokine signaling and HIV-1 fusion mediated by macrophage CXCR4: implications for target cell tropism

2000 • 28 citations

Neutralization and Enhancement of HIV-1 Infection by Sera from HIV-1 Infected Individuals Who Progress to Disease at Different Rates

2000 • 20 citations

Increased Neutralization Sensitivity and Reduced Replicative Capacity of Human Immunodeficiency Virus Type 1 after Short-Term In Vivo or In Vitro Passage through Chimpanzees

2000 • 14 citations

Genetic Diversity of Primary HIV-1 Isolates and Their Sensitivity to Antibody-Mediated Neutralization

2000 • 9 citations