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Prevention of HIV-1 infection in chimpanzees by gpl20 V3 domain-specific monoclonal antibody

Data up to Jan 2025

Published1992
Citations481
References16

Total Citations Per Year

Abstract

References (16)

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Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120.

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Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees.

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1990 • 358 citations

Immunization of chimpanzees confers protection against challenge with human immunodeficiency virus.

1991 • 357 citations

Human immunodeficiency virus neutralizing antibodies recognize several conserved domains on the envelope glycoproteins

1987 • 301 citations

Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4

1988 • 231 citations

Effects of anti-gp120 monoclonal antibodies on CD4 receptor binding by the env protein of human immunodeficiency virus type 1

1988 • 163 citations

Antibody-mediated in vitro neutralization of human immunodeficiency virus type 1 abolishes infectivity for chimpanzees

1990 • 156 citations

Immunodominant B-cell epitopes of the HIV-1 envelope recognized by infected and immunized hosts

1988 • 71 citations

Antibodies from Human Immunodeficiency Virus-Infected Individuals Bind to a Short Amino Acid Sequence that Elicits Neutralizing Antibodies in Animals

1989 • 62 citations

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Prevention of HIV-1 infection in chimpanzees by gpl20 V3 domain-specific monoclonal… (1992) – Nature | Metascience Observatory Explorer