Fluid Shear Stress Effects on Endothelial Cell Cytosolic pH

Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ

1979 • 2,166 citations

Signaling through phosphatidylcholine breakdown.

1990 • 1,362 citations

Haemodynamic shear stress activates a K+ current in vascular endothelial cells

1988 • 1,003 citations

Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells.

1994 • 576 citations

Fluid Flow Stimulates Tissue Plasminogen Activator Secretion by Cultured Human Endothelial Cells

1989 • 448 citations

Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH

1984 • 447 citations

Fluid shear stress induces a biphasic response of human monocyte chemotactic protein 1 gene expression in vascular endothelium.

1994 • 389 citations

Shear stress regulates endothelin-1 release via protein kinase C and cGMP in cultured endothelial cells

1993 • 386 citations

Shear stress induced stimulation of mammalian cell metabolism

1988 • 370 citations

Shear stress-induced reorganization of the surface topography of living endothelial cells imaged by atomic force microscopy.

1994 • 343 citations

Metabolism of adenine nucleotides by ectoenzymes of vascular endothelial and smooth-muscle cells in culture

1980 • 334 citations

Fluorescence ratio imaging microscopy: temporal and spatial measurements of cytoplasmic pH

1987 • 302 citations

Tissue plasminogen activator messenger RNA levels increase in cultured human endothelial cells exposed to laminar shear stress

1990 • 276 citations

Shear stress elevates endothelial cGMP. Role of a potassium channel and G protein coupling.

1993 • 260 citations

Control of intracellular pH and growth by fibronectin in capillary endothelial cells.

1990 • 241 citations

Angiotensin II-stimulated Na+/H+ exchange in cultured vascular smooth muscle cells. Evidence for protein kinase C-dependent and -independent pathways.

1987 • 228 citations

Shear stress increases inositol trisphosphate levels in human endothelial cells

1990 • 215 citations

Rapid release of endothelin and ATP from isolated aortic endothelial cells exposed to increased flow

1990 • 211 citations

Response of cultured endothelial cells to steady flow

1984 • 209 citations

Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange.

1985 • 203 citations

Pulsatile and steady flow induces c‐fos expression in human endothelial cells

1993 • 203 citations

Fluid flow decreases preproendothelin mRNA levels and suppresses endothelin-1 peptide release in cultured human endothelial cells

1991 • 198 citations

Flow modulation of agonist (ATP)-response (Ca2+) coupling in vascular endothelial cells

1991 • 186 citations

Flow-induced changes in Ca2+ signaling of vascular endothelial cells: effect of shear stress and ATP

1991 • 174 citations

Amiloride Directly Inhibits the Na,K-ATPase Activity of Rabbit Kidney Proximal Tubules

1983 • 172 citations

Na+-H+ exchange in gastric glands as measured with a cytoplasmic-trapped, fluorescent pH indicator.

1984 • 166 citations

Nucleotide Metabolism by Endothelium

1985 • 164 citations

Multiple integrins share the ability to induce elevation of intracellular pH*1

1991 • 161 citations

Amiloride directly inhibits growth factor receptor tyrosine kinase activity.

1985 • 155 citations

Characterization of potent sodium/proton exchange inhibitors from the amiloride series in A431 cells

1984 • 144 citations

Hydrodynamic shear stress and mass transport modulation of endothelial cell metabolism

1991 • 142 citations

Shear‐induced platelet‐derived growth factor gene expression in human endothelial cells is mediated by protein kinase C

1992 • 134 citations

Shear stress-mediated changes in the expression of leukocyte adhesion receptors on human umbilical vein endothelial cellsin vitro

1995 • 133 citations

Flow-Dependent Cytosolic Acidification of Vascular Endothelial Cells

1992 • 119 citations

Na+H+ Exchange

2017 • 117 citations

Relations among sodium pump inhibition, Na-Ca and Na-H exchange activities, and Ca-H interaction in cultured chick heart cells.

1987 • 112 citations

Flow-related responses of intracellular inositol phosphate levels in cultured aortic endothelial cells.

1993 • 107 citations

Amiloride, protein synthesis, and activation of quiescent cells

1982 • 94 citations

Fluid Shear Stress Stimulates Membrane Phospholipid Metabolism in Cultured Human Endothelial Cells

1992 • 93 citations

Optical microscopy : emerging methods and applications

1993 • 87 citations

Intracellular pH regulation in cultured embryonic chick heart cells. Na(+)-dependent Cl-/HCO3- exchange.

1990 • 84 citations

Effects of intracellular acidosis on [Ca2+]i transients, transsarcolemmal Ca2+ fluxes, and contraction in ventricular myocytes.

1990 • 75 citations

Inositol phosphates turnover, cytosolic Ca++ and pH: Putative signals for the control of cell growth

1986 • 72 citations

Intracellular alkalinization leads to Ca2+ mobilization from agonist-sensitive pools in bovine aortic endothelial cells.

1990 • 68 citations

The effect of shear stress on the uptake and metabolism of arachidonic acid by human endothelial cells

1989 • 63 citations

Influence of carbon dioxide on level of ionised calcium in squid axons

1978 • 62 citations

Endothelial cell signaling and cytoskeletal changes in response to shear stress.

1993 • 60 citations

pH dependence of actin self-assembly

1989 • 60 citations

Regulation of cytoplasmic pH of cultured bovine corneal endothelial cells in the absence and presence of bicarbonate

1988 • 59 citations

Intracellular pH changes of cultured bovine aortic endothelial cells in response to ATP addition

1988 • 56 citations

Fluid Shear Stress Induces Synthesis and Nuclear Localization of c-fos in Cultured Human Endothelial Cells

1993 • 55 citations

Convective Mass Transfer Effects on the Intracellular Calcium Response of Endothelial Cells

1992 • 55 citations

Propionic acid‐induced calcium mobilization in human neutrophils

1988 • 55 citations

Amiloride-sensitive Na+ pathways in capillary endothelial cell swelling during hemorrhagic shock

1992 • 50 citations

Amiloride and Its Analogs: Unique Cation Transport Inhibitors

1992 • 45 citations

Osmotic activation of Na(+)-H+ exchange in human endothelial cells

1990 • 45 citations

Calcium mobilization by cadmium or decreasing extracellular Na+ or pH in coronary endothelial cells

1991 • 44 citations

Increased Shear Stress Leads to Differential Release of Endothelin and ATP from Isolated Endothelial Cells from 4- and 12-Month-Old Male Rabbit Aorta

1992 • 44 citations

Comparison of tissue-cultured bovine endothelial cells from aorta and sphenous vein

1978 • 42 citations

1992 ALZA distinguished lecture: Bioengineering and vascular biology

1994 • 42 citations

Regulation of Genetic Expression in Shear Stress–stimulated Endothelial Cellsa

1992 • 42 citations

Effect of shear stress on86Rb+ efflux from calf pulmonary artery endothelial cells

1993 • 39 citations

A computer-based servo system for controlling isotonic contractions of muscle

1993 • 37 citations

Protein kinase C-mediated intracellular alkalinization in rat and rabbit aortic smooth muscle cells

1987 • 31 citations

Relationship between intracellular pH (pHi) and calcium (Cai2+) in avian heart fibroblasts

1990 • 30 citations

Cytosolic free calcium spiking affected by intracellular pH change

1990 • 28 citations

Fluid flow decreases preproendothelin mRNA levels and suppresses endothelin-1 peptide release in cultured human endothelial cells

1991 • 24 citations

Depolarization-induced alkalinization in proximal tubules. II. Effects of lactate and SITS

1989 • 19 citations

Modulation by extracellular pH of bradykinin-evoked activation of Ca(2+)-activated K+ channels in endothelial cells

1991 • 15 citations

FLUORESCENCE RATIO IMAGING: ISSUES AND ARTIFACTS

1993 • 9 citations

Intracellular pH of Tissue-Cultured Bovine Corneal Endothelial Cells

1992 • 6 citations

Technique for visualization and quantification of three dimensional intracellular ion measurements in vascular endothelial cells

1995 • 5 citations

Effect of pH on endothelin-1 secretion of aortic strips.

1993 • 5 citations

Membrane Phospholipid Metabolism in Sheared Endothelial Cells

1990 • 4 citations