SPECT Quantification of [¹²³I]Iomazenil Binding to Benzodiazepine Receptors in Nonhuman Primates: II. Equilibrium Analysis of Constant Infusion Experiments and Correlation with in vitro Parameters

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography

1984 • 959 citations

Quantitative Analysis of D2 Dopamine Receptor Binding in the Living Human Brain by PET

1986 • 847 citations

Kinetic Analysis of Central [¹¹C]Raclopride Binding to D₂-Dopamine Receptors Studied by PET—A Comparison to the Equilibrium Analysis

1989 • 454 citations

Comparison of Bolus and Infusion Methods for Receptor Quantitation: Application to [¹⁸F]Cyclofoxy and Positron Emission Tomography

1993 • 366 citations

SPECT imaging of dopamine and serotonin transporters with [¹²³I]β‐CIT: Pharmacological characterization of brain uptake in nonhuman primates

1993 • 357 citations

Compartmental Analysis of [¹¹C]Flumazenil Kinetics for the Estimation of Ligand Transport Rate and Receptor Distribution Using Positron Emission Tomography

1991 • 344 citations

Multicompartmental Analysis of [¹¹C]-Carfentanil Binding to Opiate Receptors in Humans Measured by Positron Emission Tomography

1989 • 194 citations

Regional Specific Binding of [¹¹C]RO 15 1788 to Central Type Benzodiazepine Receptors in Human Brain: Quantitative Evaluation by PET

1988 • 118 citations

Opiate antagonist receptor binding in vivo: evidence for a new receptor binding model

1980 • 100 citations

Kinetic Modeling of Receptor‐Ligand Binding Applied to Positron Emission Tomographic Studies with Neuroleptic Tracers

1987 • 98 citations

Plasma binding and transport of diazepam across the blood-brain barrier. No evidence for in vivo enhanced dissociation.

1989 • 92 citations

SPECT Quantification of [¹²³I]Iomazenil Binding to Benzodiazepine Receptors in Nonhuman Primates: I. Kinetic Modeling of Single Bolus Experiments

1994 • 81 citations

Kinetics of binding to opiate receptors in vivo predicted from in vitro parameters

1984 • 66 citations

Quantitative in vivo receptor binding. I. Theory and application to the muscarinic cholinergic receptor

1985 • 47 citations

Regional Brain Measurement of B_max and K_D with the Opiate Antagonist Cyclofoxy: Equilibrium Studies in the Conscious Rat

1991 • 45 citations

DESIGN: Computerized optimization of experimental design for estimating Kd and Bmax in ligand binding experiments

1988 • 44 citations

Single photon emission tomography measurement of benzodiazepine receptor number and affinity in primate brain: a constant infusion paradigm with [123I]iomazenil

1993 • 35 citations

SPECT imaging of the benzodiazepine receptor in non-human primate brain with [123I]Ro 16-0154

1991 • 33 citations

Quantitative in vivo analysis of benzodiazepine binding sites in the human brain using positron emission tomography

1991 • 29 citations

Quantitative evaluation of benzodiazepine receptors in live Papio papio baboons using positron emission tomography.

1990 • 22 citations

Formation of 1-[123I]iodobutane in labeling [123I]iomazenil by iododestannylation: Implications for the reaction mechanism

1994 • 20 citations

SPECT Imaging of the benzodiazepine receptor: Autoradiographic comparison of receptor density and radioligand distribution

1992 • 13 citations

D-amphetamine displacement of [123I]IBF equilibrium binding in primates: A new paradigm to investigate D-amphetamine induced dopamine release.

1993 • 2 citations