Regional Brain Measurement of B_max and K_D with the Opiate Antagonist Cyclofoxy: Equilibrium Studies in the Conscious Rat

THE [¹⁴C]DEOXYGLUCOSE METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE UTILIZATION: THEORY, PROCEDURE, AND NORMAL VALUES IN THE CONSCIOUS AND ANESTHETIZED ALBINO RAT¹

1977 • 5,986 citations

Pharmacokinetics

1982 • 3,815 citations

Problems of Drug Dependence

1969 • 970 citations

A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography

1984 • 959 citations

Quantitative Analysis of D2 Dopamine Receptor Binding in the Living Human Brain by PET

1986 • 847 citations

Transport of α-Aminoisobutyric Acid across Brain Capillary and Cellular Membranes

1983 • 510 citations

Kinetic Analysis of Central [¹¹C]Raclopride Binding to D₂-Dopamine Receptors Studied by PET—A Comparison to the Equilibrium Analysis

1989 • 454 citations

Autoradiographic localization of the opiate receptor in rat brain

1975 • 387 citations

Quantification of Neuroreceptors in the Living Human Brain. I. Irreversible Binding of Ligands

1986 • 279 citations

PET analysis of human dopamine receptor subtypes using 11C-SCH 23390 and 11C-raclopride

1987 • 279 citations

Multicompartmental Analysis of [¹¹C]-Carfentanil Binding to Opiate Receptors in Humans Measured by Positron Emission Tomography

1989 • 194 citations

Quantification of Neuroreceptors in the Living Human Brain. II. Inhibition Studies of Receptor Density and Affinity

1986 • 147 citations

Strategies for in vivo Measurement of Receptor Binding Using Positron Emission Tomography

1986 • 135 citations

A method to obtain infusion schedules for prescribed blood concentration time courses

1976 • 104 citations

Kinetic Modeling of Receptor‐Ligand Binding Applied to Positron Emission Tomographic Studies with Neuroleptic Tracers

1987 • 98 citations

Plasma binding and transport of diazepam across the blood-brain barrier. No evidence for in vivo enhanced dissociation.

1989 • 92 citations

Quantitation of Photochemically Induced Focal Cerebral Ischemia in the Rat

1988 • 90 citations

Comparison of [¹¹C]Diprenorphine and [¹¹C]Carfentanil Binding to Opiate Receptors in Humans by Positron Emission Tomography

1990 • 81 citations

S‐[¹⁸F]Acetylcyclofoxy: a useful probe for the visualization of opiate receptors in living animals

1984 • 59 citations

Kinetic Analysis of 3-Quinuclidinyl 4-[¹²⁵I]Iodobenzilate Transport and Specific Binding to Muscarinic Acetylcholine Receptor in Rat Brain in vivo: Implications for Human Studies

1990 • 53 citations

Intracellular pH and buffering power of rat brain

1971 • 50 citations

Quantitative in vivo receptor binding. I. Theory and application to the muscarinic cholinergic receptor

1985 • 47 citations

Quantitative in vivo receptor binding III: Tracer kinetic modeling of muscarinic cholinergic receptor binding.

1985 • 46 citations

Simultaneous Quantitation of Lidocaine and Its Four Metabolites by High-performance Liquid Chromatography: Application to studies on In Vitro and In Vivo Metabolism of Lidocaine in Rats

1985 • 44 citations

An examination of the opiate receptor subtypes labeled by [3H]cyclofoxy: An opiate antagonist suitable for positron emission tomography

1988 • 32 citations

Binding of radiolabeled opiates to slide-mounted sections of molded minced rat brain: A novel method for conducting radioreceptor assays

1983 • 32 citations

A brief study of the selectivity of norbinaltorphimine, (−)-cyclofoxy, and (+)-cyclofoxy among opioid receptor subtypes in vitro

1988 • 27 citations

Radiosynthesis of [18F]3-acetylcyclofoxy: a high affinity opiate antagonist

1985 • 27 citations

The pattern of [3H]cyclofoxy retention in rat brain after in vivo injection corresponds to the in vitro opiate receptor distribution

1987 • 27 citations

Probes for Narcotic Receptor Mediated Phonomena 11. Synthesis of 17-Methyl and 17-Cyclopropylmethyl-3,14-dihydroxy-4,5a-epoxy-6b-fluoromorphinans (Foxy and Cyclofoxy) as Models of Opioid Ligands Suitable for Position Emission Transaxial Tomography

1985 • 24 citations

Kinetic analysis of the opiate antagonist cyclofoxy in rat brain: simultaneous infusion of active and inactive enantiomers.

1990 • 20 citations

Kinetic Analysis of Transport and Opioid Receptor Binding of [³H](−)-Cyclofoxy in Rat Brain in vivo: Implications for Human Studies

1991 • 16 citations

In vivo Binding of Spiperone and N-Methylspiperone to Dopaminergic and Serotonergic Sites in the Rat Brain: Multiple Modeling and Implications for PET Scanning

1990 • 10 citations

A convenient procedure for preparing naltrexone‐15,16‐³H₂ and naloxone‐15‐³H of high specific activity

1976 • 8 citations