Regulation and function of Gα protein subunits in Dictyostelium

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart

1987 • 1,186 citations

Roles of G protein subunits in transmembrane signalling

1988 • 794 citations

A Chemoattractant Receptor Controls Development in Dictyostelium discoideum

1988 • 465 citations

The yeast SCG1 gene: A Gα-like protein implicated in the a- and α-factor response pathway

1987 • 431 citations

Antisera of designed specificity for subunits of guanine nucleotide-binding regulatory proteins.

1986 • 380 citations

GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction

1987 • 365 citations

Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain

1988 • 326 citations

Control of cell-contact sites by cyclic AMP pulses in differentiating Dictyostelium cells

1975 • 320 citations

DNA-Mediated Transformation in Dictyostelium discoideum: Regulated Expression of an Actin Gene Fusion

1984 • 277 citations

G protein multiplicity in eukaryotic signal transduction systems

1988 • 267 citations

From Epinephrine to Cyclic AMP

1988 • 255 citations

CYCLIC AMP AND OTHER SIGNALS CONTROLLING CELL DEVELOPMENT AND DIFFERENTIATION IN DICTYOSTELIUM

1987 • 240 citations

Phenocopy of discoidin I-minus mutants by antisense transformation in Dictyostelium

1985 • 225 citations

Chapter 4 Molecular Biology in Dictyostelium: Tools and Applications

1987 • 223 citations

DNA-mediated transformation in Dictyostelium discoideum: regulated expression of an actin gene fusion.

1984 • 199 citations

Molecular basis of transmembrane signal transduction in Dictyostelium discoideum

1987 • 186 citations

Genetic regulation of development

1987 • 147 citations

Surface receptor-mediated activation of adenylate cyclase in Dictyostelium. Regulation by guanine nucleotides in wild-type cells and aggregation deficient mutants.

1986 • 144 citations

Cyclic AMP Regulation of Early Gene Expression in Dictyostelium discoideum: Mediation via the Cell Surface Cyclic AMP Receptor

1987 • 127 citations

High-copy-number transformants and co-transformation in Dictyostelium

1985 • 126 citations

Signal transduction in Dictyostelium fgd A mutants with a defective interaction between surface cAMP receptors and a GTP-binding regulatory protein [published erratum appears in J Cell Biol 1988 Dec;107(6 Pt 1):following 2463]

1988 • 124 citations

Molecular approaches to developmental biology

1986 • 116 citations

The role of diffusible molecules in regulating the cellular differentiation ofDictyostelium discoideum

1988 • 99 citations

Ligand-induced phosphorylation of the cAMP receptor from Dictyostelium discoideum.

1988 • 99 citations

The surface cyclic AMP receptor in Dictyostelium. Levels of ligand-induced phosphorylation, solubilization, identification of primary transcript, and developmental regulation of expression.

1987 • 96 citations

DNA sequences required for expression of a Dictyostelium actin gene.

1986 • 94 citations

Two-phase regulatory pathway controls cAMP receptor-mediated expression of early genes in Dictyostelium.

1989 • 93 citations

Chapter 17 Transmembrane Signaling in Dictyostelium

1987 • 90 citations

Regulation of size and pattern in the cellular slime molds

1986 • 78 citations

Cyclic AMP regulation of early gene expression in Dictyostelium discoideum: mediation via the cell surface cyclic AMP receptor.

1987 • 76 citations

The regulation of adenylate cyclase by guanine nucleotides in Dictyostelium discoideum membranes

1987 • 75 citations

G-protein-mediated interconversions of cell-surface cAMP receptors and their involvement in excitation and desensitization of guanylate cyclase in Dictyostelium discoideum.

1986 • 74 citations

Isolation and characterization of cAMP unresponsive (frigid) aggregation‐deficient mutants of Dictyostelium discoideum

1982 • 71 citations

Developmental consequences of the lack of myosin heavy chain in Dictyostelium discoideum

1988 • 71 citations

Molecular basis of transmembrane signal transduction in Dictyostelium discoideum.

1987 • 61 citations

cAMP regulation of early gene expression in signal transduction mutants of Dictyostelium

1988 • 59 citations

Inositol phosphates, G-proteins and RAS genes involved in chemotactic signal transduction of Dictyostelium

1988 • 57 citations

Specific photoaffinity labeling of the cAMP surface receptor in Dictyostelium discoideum.

1984 • 49 citations

Early Dictyostelium Development: Control Mechanisms Bypassed by Sequential Mutagenesis

1985 • 47 citations

Regulation of Cell-type-specific Gene Expression in Dictyostelium

1985 • 42 citations

The specificity of the cAMP receptor mediating activation of adenylate cyclase in Dictyostelium discoideum

1986 • 41 citations

Molecular analysis of a developmentally regulated gene required for dictyostelium aggregation

1989 • 33 citations

cAMP Receptors Controlling Cell-Cell Interactions in the Development of Dictyostelium

1985 • 31 citations

Physiological and biochemical characterization of aggregation-deficient mutants of Dictyostelium discoideum: detection and response to exogenous cyclic AMP

1978 • 28 citations

Pertussis toxin inhibits cAMP surface receptor‐stimulated binding of [³⁵S]GTPγS to Dictyostelium discoideum membranes

1988 • 23 citations

Immunological detection of G-protein α-subunits in Dictyostelium discoideum

1988 • 18 citations

Pertussis and cholera toxin ADP-ribosylation in dictyostelium discoideum membranes

1987 • 17 citations