Enhanced expression of transforming growth factor-beta type I and type II receptors in wound granulation tissue and hypertrophic scar.

Transforming Growth Factor β in Tissue Fibrosis

1994 • 3,055 citations

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

1993 • 2,169 citations

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

1987 • 1,287 citations

Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing.

1990 • 1,176 citations

Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar.

1995 • 1,167 citations

TGFβ Signaling: Receptors, Transducers, and Mad Proteins

1996 • 840 citations

Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta.

1987 • 791 citations

Physiological Actions and Clinical Applications of Transforming Growth Factor-β (TGF-β)

1993 • 755 citations

GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex.

1995 • 682 citations

Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex.

1990 • 647 citations

Control of scarring in adult wounds by neutralising antibody to transforming growth factor β

1992 • 624 citations

Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells.

1988 • 604 citations

Morphological and immunochemical differences between keloid and hypertrophic scar.

1994 • 522 citations

Immunohistochemical localization of growth factors in fetal wound healing

1991 • 418 citations

The extracellular matrix of lip wounds in fetal, neonatal and adult mice

1991 • 396 citations

Transforming Growth Factors β1, β2, and β3 and Their Receptors Are Differentially Regulated during Normal and Impaired Wound Healing

1996 • 349 citations

Activation of Signalling by the Activin Receptor Complex

1996 • 317 citations

Activation of Collagen Gene Expression in Keloids: Co-Localization of Type I and VI Collagen and Transforming Growth Factor-β1 mRNA

1991 • 250 citations

The Histiotypic Organization of the Hypertrophic Scar in Humans

1972 • 179 citations

Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin: incisional wound model.

1991 • 159 citations

Transforming growth factor‐β: activity and efficacy in animal models of wound healing

1995 • 159 citations

Pericytes as collagen-producing cells in excessive dermal scarring.

1996 • 157 citations

Evaluation of Transforming Growth Factor β and Type I Procollagen Gene Expression in Fibrotic Skin Disease by In Situ Hybridization

1990 • 155 citations

Increased Types I and III Collagen and Transforming Growth Factor-β1 mRNA and Protein in Hypertrophic Burn Scar

1995 • 152 citations

Enhanced expression of mRNA for transforming growth factor-beta, type I and type III procollagen in human post-burn hypertrophic scar tissues.

1993 • 150 citations

Macrophage Production of TGF-? and Regulation by TGF-?

1990 • 149 citations

Transforming growth factor-beta stimulates wound healing and modulates extracellular matrix gene expression in pig skin. I. Excisional wound model.

1990 • 138 citations

Immunohistochemical localization of the proteoglycans decorin, biglycan and versican and transforming growth factor‐β in human post‐burn hypertrophic and mature scars

1995 • 125 citations

Autoinduction of Transforming Growth Factor β1 Is Mediated by the AP-1 Complex

1990 • 99 citations

MAD-related proteins in TGF-β signalling

1996 • 92 citations

Type I (RI) and type II (RII) receptors for transforming growth factor-beta isoforms are expressed subsequent to transforming growth factor-beta ligands during excisional wound repair.

1997 • 75 citations

Heterogeneity in hormone responses and patterns of collagen synthesis in cloned dermal fibroblasts.

1990 • 73 citations

Phenotypic Differences in Cytokine Responsiveness of Hypertrophic Scar Versus Normal Dermal Fibroblasts

1993 • 72 citations

Histologic basis of keloid and hypertrophic scar differentiation. Clinicopathologic correlation.

1966 • 68 citations

Structure and expression of the promoter for the R4/ALK5 human type I transforming growth factor-β receptor: regulation by TGF-β

1996 • 62 citations

Human Granulation-tissue Fibroblasts Show Enhanced Proteoglycan Gene Expression and Altered Response to TGF-β1

1996 • 57 citations

In situ analysis of transforming growth factor-βs (TGF-β1, TGF-β2, TGF-β3and TGF-3 type II receptor expression in malignant melanoma

1995 • 55 citations

Fibroblast heterogeneity in the healing wound

1995 • 54 citations

Injury Induced Expression of TGF-β1 mRNA Is Enhanced by Exogenously Applied TGF-βS

1993 • 37 citations

Recruitment of Type I Collagen Producing Cells from the Microvasculaturein Vitro

1996 • 33 citations

Collagen type I is not under autocrine control by transforming growth factor-beta 1 in normal and scleroderma fibroblasts.

1994 • 31 citations