A Soluble Fn14-Fc Decoy Receptor Reduces Infarct Volume in a Murine Model of Cerebral Ischemia

The Mouse Brain in Stereotaxic Coordinates

2001 • 12,804 citations

Pathobiology of ischaemic stroke: an integrated view

1999 • 3,776 citations

Activators and Target Genes of Rel/NF-кB Transcription Factors

2003 • 3,164 citations

HIF-1 and human disease: one highly involved factor

2000 • 900 citations

Inflammation and glial responses in ischemic brain lesions

1998 • 788 citations

TWEAK, a New Secreted Ligand in the Tumor Necrosis Factor Family That Weakly Induces Apoptosis

1997 • 666 citations

A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia

2003 • 656 citations

NF-κB is activated and promotes cell death in focal cerebral ischemia

1999 • 648 citations

Hypoxia-Induced Vascular Endothelial Growth Factor Expression Precedes Neovascularization after Cerebral Ischemia

2000 • 641 citations

Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor–related protein

2003 • 509 citations

MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia

1999 • 468 citations

Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor–related protein

2003 • 430 citations

Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia

2001 • 364 citations

A Novel TNF Receptor Family Member Binds TWEAK and Is Implicated in Angiogenesis

2001 • 364 citations

Signaling of Cell Death and Cell Survival Following Focal Cerebral Ischemia: Life and Death Struggle in the Penumbra

2003 • 341 citations

TWEAK Induces NF-κB2 p100 Processing and Long Lasting NF-κB Activation

2003 • 304 citations

Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia.

1987 • 302 citations

TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor

2003 • 271 citations

Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis

2000 • 262 citations

Role of Plasminogen System Components in Focal Cerebral Ischemic Infarction

1999 • 250 citations

Fibroblast Growth Factor-Inducible-14 Is Induced in Axotomized Neurons and Promotes Neurite Outgrowth

2003 • 199 citations

The Mitogen-inducible Fn14 Gene Encodes a Type I Transmembrane Protein that Modulates Fibroblast Adhesion and Migration

1999 • 196 citations

The Fn14 Immediate-Early Response Gene Is Induced During Liver Regeneration and Highly Expressed in Both Human and Murine Hepatocellular Carcinomas

2000 • 182 citations

The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation

2003 • 174 citations

Effect of Lipopolysaccharide on the Morphology and Integrin Immunoreactivity of Ramified Microglia in the Mouse Brain and in Cell Culture

2001 • 169 citations

Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells

2002 • 167 citations

TWEAK Is an Endothelial Cell Growth and Chemotactic Factor That Also Potentiates FGF-2 and VEGF-A Mitogenic Activity

2003 • 156 citations

Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies

2001 • 147 citations

The Human Fn14 Receptor Gene Is Up-Regulated in Migrating Glioma Cells in Vitro and Overexpressed in Advanced Glial Tumors

2003 • 141 citations

TWEAK Mediates Signal Transduction and Differentiation of RAW264.7 Cells in the Absence of Fn14/TweakR

2003 • 140 citations

TWEAK Can Induce Pro-Inflammatory Cytokines and Matrix Metalloproteinase-9 in Macrophages

2004 • 138 citations

Fibroblast Growth Factor-Inducible 14 Mediates Multiple Pathways of TWEAK-Induced Cell Death

2003 • 135 citations

TWEAK stimulation of astrocytes and the proinflammatory consequences

2000 • 128 citations

TWEAK is expressed by glial cells, induces astrocyte proliferation and increases EAE severity

2002 • 125 citations

Significant Neuroprotection against Ischemic Brain Injury by Inhibition of the MEK1 Protein Kinase in Mice: Exploration of Potential Mechanism Associated with Apoptosis

2003 • 113 citations

TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-κB through TNF receptor-associated factors

2003 • 103 citations

Matrix Remodeling after Stroke: De Novo Expression of Matrix Proteins and Integrin Receptors

1999 • 103 citations

Induction of basic fibroblast growth factor (bFGF) expression following focal cerebral ischemia

1997 • 98 citations

Therapeutic potential of anti-inflammatory drugs in focal stroke

2000 • 80 citations

TWEAK/Fn14 interaction stimulates human bronchial epithelial cells to produce IL-8 and GM-CSF

2004 • 71 citations

Current and Future Therapeutic Strategies to Target Inflammation in Stroke

2002 • 53 citations

Recombinant adenoviral expression of dominant negative IκBα protects brain from cerebral ischemic injury

2002 • 37 citations

Progressive Ankylosis (Ank) Protein Is Expressed by Neurons and Ank Immunohistochemical Reactivity Is Increased by Limbic Seizures

2003 • 25 citations