The Structure of the Human Immunodeficiency Virus Type-1 TAR RNA Reveals Principles of RNA Recognition by Tat Protein

Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins

1983 • 3,150 citations

Computer-optimized decoupling scheme for wideband applications and low-level operation

1985 • 1,104 citations

Arginine-Mediated RNA Recognition: the Arginine Fork

1991 • 757 citations

[22] absorbance melting curves of RNA

1989 • 620 citations

Comparison of different modes of two-dimensional reverse-correlation NMR for the study of proteins

1990 • 510 citations

A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated trans-activation.

1990 • 412 citations

Structure of an unusually stable RNA hairpin

1991 • 368 citations

Heteronuclear filters in two-dimensional [¹H, ¹H]-NMR spectroscopy: combined use with isotope labelling for studies of macromolecular conformation and intermolecular interactions

1990 • 354 citations

Analysis of arginine-rich peptides from the HIV Tat protein reveals unusual features of RNA-protein recognition.

1991 • 328 citations

Structure of the P1 Helix from Group I Self-splicing Introns

1995 • 281 citations

Preparation of isotopically labeled ribonucleotides for multidimensional NMR spectroscopy of RNA

1992 • 271 citations

Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein

1989 • 270 citations

RNA recognition by an isolated α helix

1993 • 265 citations

RNA structure and NMR spectroscopy

1991 • 259 citations

The conformation of loop E of eukaryotic 5S ribosomal RNA

1993 • 229 citations

Major Groove Accessibility of RNA

1993 • 202 citations

Role of RNA structure in arginine recognition of TAR RNA.

1993 • 191 citations

Structural studies of HIV-1 tat protein

1995 • 191 citations

On the multiple simultaneous superposition of molecular structures by rigid body transformations

1992 • 113 citations

Equine infectious anemia virus tat: insights into the structure, function, and evolution of lentivirus trans-activator proteins

1990 • 112 citations

Hydrogen-bonding Contacts in the Major Groove are required for Human Immunodeficiency Virus Type-1 tat Protein Recognition of TAR RNA

1993 • 109 citations

Three-dimensional 13C-resolved proton NOE spectroscopy of uniformly 13C-labeled proteins for the NMR assignment and structure determination of larger molecules

1990 • 97 citations

Divalent metal ion binding to a conserved wobble pair defining the upstream site of cleavage of group I self-splicing introns

1995 • 96 citations

Conserved nucleotides in the TAR RNA stem of human immunodeficiency virus type 1 are critical for Tat binding and trans activation: model for TAR RNA tertiary structure

1992 • 85 citations

The number of positively charged amino acids in the basic domain of Tat is critical for trans-activation and complex formation with TAR RNA.

1991 • 76 citations

Two- and three-dimensional 31P-driven NMR procedures for complete assignment of backbone resonances in oligodeoxyribonucleotides

1993 • 70 citations

An NMR study of the HIV-1 TAR element hairpin

1993 • 64 citations

Correlation of nucleotide base and sugar protons in a 15N-labeled HIV-1 RNA oligonucleotide by 1H-15N HSQC experiments

1994 • 64 citations

Structure of the Equine Infectious Anemia Virus Tat Protein

1994 • 52 citations

Refolded HIV-1 tat protein protects both bulge and loop nucleotides in TAR RNA from ribonucleolytic cleavage

1991 • 42 citations

Novel three-dimensional 1H?13C?31P triple resonance experiments for sequential backbone correlations in nucleic acids

1995 • 32 citations

Second Exon of Tat of HIV-2 Is Required for Optimal Trans-Activation of HIV-1 and HIV-2 LTRs

1993 • 25 citations

Optimization of baseline and folding in spectra obtained using the TPPI format

1992 • 7 citations