Refolded HIV-1 tat protein protects both bulge and loop nucleotides in TAR RNA from ribonucleolytic cleavage

Cellular uptake of the tat protein from human immunodeficiency virus

1988 • 2,690 citations

Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism

1986 • 730 citations

Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator protein

1987 • 672 citations

Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro.

1988 • 603 citations

HIV-1 Tat protein increases transcriptional initiation and stabilizes elongation

1989 • 577 citations

HIV-1 tat trans-activation requires the loop sequence within tar

1988 • 551 citations

The HIV tat gene induces dermal lesions resembling Kaposi's sarcoma in transgenic mice

1988 • 532 citations

Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro.

1989 • 472 citations

Tat Protein from Human Immunodeficiency Virus Forms a Metal-Linked Dimer

1988 • 464 citations

Fragments of the HIV-1 Tat Protein Specifically Biand TAR RNA

1990 • 446 citations

A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated trans-activation.

1990 • 412 citations

Regulatory pathways governing HIV-1 replication

1989 • 401 citations

Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-1 long terminal repeat.

1989 • 357 citations

HIV-1 regulator of virion expression (Rev) protein binds to an RNA stem-loop structure located within the Rev response element region

1990 • 354 citations

Characteristic ribonucleolytic activity of human angiogenin

1986 • 354 citations

Analysis of arginine-rich peptides from the HIV Tat protein reveals unusual features of RNA-protein recognition.

1991 • 328 citations

HIV-1 Tat protein trans-activates transcription in vitro

1990 • 277 citations

Expression and Characterization of the Trans -Activator of HTLV-III/LAV Virus

1986 • 276 citations

TAR-independent activation of the HIV-1 LTR: Evidence that Tat requires specific regions of the promoter

1990 • 253 citations

Trans-activation by HIV-1 Tat via a heterologous RNA binding protein

1990 • 236 citations

Mutational analysis of the trans-activation-responsive region of the human immunodeficiency virus type I long terminal repeat

1988 • 235 citations

trans activation of human immunodeficiency virus type 1 is sequence specific for both the single-stranded bulge and loop of the trans-acting-responsive hairpin: a quantitative analysis

1989 • 224 citations

The HIV-1 Tat protein: An RNA sequence-specific processivity factor?

1990 • 220 citations

Identification and characterization of a HeLa nuclear protein that specifically binds to the trans-activation-response (TAR) element of human immunodeficiency virus.

1990 • 217 citations

Activation of transcription by HIV-1 Tat protein tethered to nascent RNA through another protein

1990 • 192 citations

Sequence-specific interaction of Tat protein and Tat peptides with the transactivation-responsive sequence element of human immunodeficiency virus type 1 in vitro.

1990 • 176 citations

HIV TAR: An RNA enhancer?

1989 • 175 citations

Transcriptional but not translational regulation of HIV-1 by the tat gene product

1988 • 158 citations

Synthesis of the complete trans-activation gene product of human T-lymphotropic virus type III in Escherichia coli: demonstration of immunogenicity in vivo and expression in vitro.

1986 • 90 citations

Transcription by T7 RNA polymerase is not zinc-dependent and is abolished on amidomethylation of cysteine-347

1986 • 85 citations

T7 RNA polymerase does not interact with the 5'-phosphate of the initiating nucleotide

1989 • 62 citations

In vivo enzymology: a deuterium NMR study of formaldehyde dismutase in Pseudomonas putida F61a and Staphylococcus aureus

1989 • 26 citations

Enzymically active angiogenin/ribonuclease A hybrids formed by peptide interchange

1988 • 26 citations

Study of the interaction of Escherichia coli methionyl-tRNA synthetase with tRNAfMet using chemical and enzymic probes

1986 • 13 citations

Synthesis and utilization of 8-azidoguanosine 3'-phosphate 5'-[5'-32P]phosphate. Photoaffinity studies on cytosolic proteins of Escherichia coli.

1984 • 4 citations