Structure-function relationships in epidermal growth factor (egf) and transforming growth factor-alpha (TGF-α)

Structure and Function of Human Amphiregulin: A Member of the Epidermal Growth Factor Family

1989 • 586 citations

Calculation of protein conformations by proton-proton distance constraints

1985 • 564 citations

Alpha-factor-directed synthesis and secretion of mature foreign proteins in Saccharomyces cerevisiae.

1984 • 477 citations

Protein Structure Determination in Solution by Nuclear Magnetic Resonance Spectroscopy

1989 • 444 citations

An evaluation of the combined use of nuclear magnetic resonance and distance geometry for the determination of protein conformations in solution

1985 • 373 citations

Efficient synthesis of enzymatically active calf chymosin in Saccharomyces cerevisiae

1983 • 337 citations

The solution structure of human epidermal growth factor

1987 • 322 citations

Epidermal growth factor and transforming growth factor α

1989 • 247 citations

Protein structures from NMR

1988 • 212 citations

The first EGF-like domain from human factor IX contains a high-affinity calcium binding site.

1990 • 190 citations

The genealogy of some recently evolved vertebrate proteins

1985 • 179 citations

Solution structure of murine epidermal growth factor: determination of the polypeptide backbone chain-fold by nuclear magnetic resonance and distance geometry.

1987 • 153 citations

Characterization of recombinant human epidermal growth factor produced in yeast

1988 • 78 citations

Cloning of authentic human epidermal growth factor as a bacterial secretory protein and its initial structure-function analysis by site-directed mutagenesis.

1988 • 71 citations

The solution structures of epidermal growth factor and transforming growth factor alpha

1989 • 67 citations

Structure-function analysis of synthetic and recombinant derivatives of transforming growth factor alpha.

1988 • 57 citations

Murine epidermal growth factor: structure and function

1988 • 57 citations

Polypeptide chain fold of human transforming growth factor .alpha. analogous to those of mouse and human epidermal growth factors as studied by two-dimensional proton NMR

1989 • 53 citations

Transforming Growth Factor α: Mutation of Aspartic Acid 47 and Leucine 48 Results in Different Biological Activities

1988 • 40 citations

Sequence-specific 1H-NMR assignments and identification of two small antiparallel beta-sheets in the solution structure of recombinant human transforming growth factor alpha.

1989 • 37 citations

Calcium binding and putative activity of the epidermal growth factor domain of blood coagulation Factor IX

1989 • 36 citations

A high‐resolution ¹H‐NMR study of human transforming growth factor α

1989 • 33 citations

Proton-NMR assignment and secondary structural elements of human transforming growth factor

1989 • 22 citations

Sequence-specific 1H-n.m.r. assignments and peptide backbone conformation in rat epidermal growth factor

1989 • 22 citations

Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities.

1988 • 22 citations

Protein structure determination by nuclear magnetic resonance

1988 • 18 citations

Conformational and receptor binding properties of human EGF and TGF‐α second loop fragments

1988 • 11 citations

Protein structure determination by NMR

1987 • 11 citations

Towards the Structure of Mosaic Proteins: Use of Protein Expression and NMR Techniques

1990 • 3 citations