Towards the Structure of Mosaic Proteins: Use of Protein Expression and NMR Techniques

NMR with Proteins and Nucleic Acids

1986 • 7,896 citations

NMR of Proteins and Nucleic Acids

2006 • 5,989 citations

Transformation of yeast.

1978 • 2,267 citations

Transformation of yeast by a replicating hybrid plasmid

1978 • 1,362 citations

Production of human beta interferon in insect cells infected with a baculovirus expression vector.

1983 • 907 citations

Structure of a yeast pheromone gene (MFα): A putative α-factor precursor contains four tandem copies of mature α-factor

1982 • 587 citations

The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins.

1986 • 575 citations

Alpha-factor-directed synthesis and secretion of mature foreign proteins in Saccharomyces cerevisiae.

1984 • 477 citations

A highly conserved amino-acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite

1988 • 386 citations

The gene structure of human anti-haemophilic factor IX.

1984 • 361 citations

The complete amino acid sequence of human complement factor H

1988 • 347 citations

Efficient synthesis of enzymatically active calf chymosin in Saccharomyces cerevisiae

1983 • 337 citations

The solution structure of human epidermal growth factor

1987 • 322 citations

Intron‐dependent evolution: Preferred types of exons and introns

1987 • 300 citations

The role of beta-hydroxyaspartate and adjacent carboxylate residues in the first EGF domain of human factor IX.

1988 • 240 citations

Protein structures from NMR

1988 • 212 citations

Properdin, the terminal complement components, thrombospondin and the circumsporozoite protein of malaria parasites contain similar sequence motifs

1988 • 189 citations

The genealogy of some recently evolved vertebrate proteins

1985 • 179 citations

Structure, Organization, and Regulation of the Complement Genes

1988 • 178 citations

Secretion of foreign proteins from Saccharomyces cerevisiae directed by alpha-factor gene fusions.

1984 • 126 citations

Three-dimensional structure of the kringle sequence: structure of prothrombin fragment 1

1986 • 124 citations

Heterologous Gene Expression inSaccharomyces cerevisiae

1985 • 109 citations

Mapping the collagen-binding site of human fibronectin by expression in Escherichia coli.

1986 • 95 citations

Detecting distant homologies of mosaic proteins

1988 • 93 citations

A synthetic approach to structure-function relationships in the murine epidermal growth factor molecule.

1986 • 91 citations

Lysine/fibrin binding sites of kringles modeled after the structure of kringle 1 of prothrombin

1988 • 81 citations

Characterization of recombinant human epidermal growth factor produced in yeast

1988 • 78 citations

The solution structures of epidermal growth factor and transforming growth factor alpha

1989 • 67 citations

Expression and secretion of biologically active human atrial natriuretic peptide in Saccharomyces cerevisiae.

1986 • 53 citations

Vitamin K-dependent blood coagulation proteins form hetero-dimers

1987 • 46 citations

Chemical synthesis and expression in yeast of a gene encoding connective tissue activating peptide-III. A novel approach for the facile assembly of a gene encoding a human platelet-derived mitogen.

1986 • 39 citations

Protein structure determination by nuclear magnetic resonance

1988 • 18 citations

Two‐dimensional ¹H‐NMR studies of the solution structure of plasminogen kringle 4

1988 • 16 citations

Protein structure determination by NMR

1987 • 11 citations

Unravelling atherosclerosis

1989 • 6 citations