The methionine allele of the COMT polymorphism impairs prefrontal cognition in children and adolescents with ADHD

The Attention System of the Human Brain

1990 • 7,582 citations

Executive Functions and Developmental Psychopathology

1996 • 3,104 citations

Effect of COMT Val ^108/158 Met genotype on frontal lobe function and risk for schizophrenia

2001 • 2,408 citations

Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes

2002 • 1,795 citations

Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders

1996 • 1,780 citations

Modulation of memory fields by dopamine Dl receptors in prefrontal cortex

1995 • 1,600 citations

Right hemispheric dominance of inhibitory control: An event-related functional MRI study

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D1 Dopamine Receptors in Prefrontal Cortex: Involvement in Working Memory

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The Child and Adolescent Psychiatric Assessment (CAPA)

1995 • 968 citations

Catechol O -methyltransferase val ¹⁵⁸ -met genotype and individual variation in the brain response to amphetamine

2003 • 900 citations

Intelligence and the Frontal Lobe: The Organization of Goal-Directed Behavior

1996 • 889 citations

The Differential Assessment of Children's Attention: The Test of Everyday Attention for Children (TEA‐Ch), Normative Sample and ADHD Performance

2001 • 662 citations

Differential patterns of striatal activation in young children with and without ADHD

2003 • 616 citations

A Functional Polymorphism in the COMT Gene and Performance on a Test of Prefrontal Cognition

2002 • 613 citations

Catecholamine modulation of prefrontal cortical cognitive function

1998 • 596 citations

Executive Subprocesses in Working Memory

2003 • 591 citations

Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder

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A Multidisciplinary Approach to Anterior Attentional Functionsa

1995 • 515 citations

Pharmacokinetics and Clinical Effectiveness of Methylphenidate

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Frontal lesions and sustained attention

1987 • 457 citations

Genetic and Neurochemical Modulation of Prefrontal Cognitive Functions in Children

2004 • 386 citations

3‐Methoxytyramine Is the Major Metabolite of Released Dopamine in the Rat Frontal Cortex: Reassessment of the Effects of Antipsychotics on the Dynamics of Dopamine Release and Metabolism in the Frontal Cortex, Nucleus Accumbens, and Striatum by a Simple Two Pool Model

1994 • 349 citations

Genomic organization of the human catechol O‐methyltransferase gene and its expression from two distinct promoters

1994 • 332 citations

Neurocognitive correlates of the COMT Val158Met polymorphism in chronic schizophrenia

2002 • 327 citations

Localization of Executive Functions in Dual-Task Performance with fMRI

2002 • 322 citations

Catechol-O-Methyltransferase Genotype and Dopamine Regulation in the Human Brain

2003 • 321 citations

Executive Function Profile of Children With Attention Deficit Hyperactivity Disorder

2002 • 299 citations

Rating scales in attention-deficit/hyperactivity disorder: use in assessment and treatment monitoring.

1998 • 283 citations

Sustained attention deficits in pat ients with right frontal lesions

1996 • 255 citations

Methylphenidate and cognitive flexibility: Dissociated dose effects in hyperactive children

1995 • 220 citations

Dopaminergic System Genes in ADHD Toward a Biological Hypothesis

2002 • 195 citations

Haplotype relative risk study of catechol-O-methyltransferase (COMT) and attention deficit hyperactivity disorder (ADHD): Association of the high-enzyme activity val allele with adhd impulsive-hyperactive phenotype

1999 • 167 citations

Association of the functional V158M catechol-O-methyl-transferase polymorphism with panic disorder in women

2004 • 156 citations

Enhancing the Sensitivity of a Sustained Attention Task to Frontal Damage: Convergent Clinical and Functional Imaging Evidence

2003 • 155 citations

Clinical Predictors of Acute Response With Olanzapine in Psychotic Mood Disorders

1998 • 134 citations

Examining for association between candidate gene polymorphisms in the dopamine pathway and attention‐deficit hyperactivity disorder: A family‐based study

2001 • 132 citations

Methylphenidate Down-Regulates the Dopamine Receptor and Transporter System in Children with Attention Deficit Hyperkinetic Disorder (ADHD)

2003 • 123 citations

Network for auditory intrinsic alertness: a PET study

2004 • 121 citations

Family‐based and case‐control association studies of catechol‐O‐methyltransferase in attention deficit hyperactivity disorder suggest genetic sexual dimorphism

2002 • 115 citations

Linkage study of Catechol-O-Methyltransferase and attention-deficit hyperactivity disorder

1999 • 97 citations

A logistic regression based extension of the TDT for continuous and categorical traits

1999 • 80 citations

Prefrontal blood flow dysregulation in drug naive ADHD children without structural abnormalities

2001 • 78 citations

The Child Attention-Deficit Hyperactivity Disorder Teacher Telephone Interview (CHATTI): reliability and validity

2003 • 74 citations

No association between catechol-O-methyltransferase (COMT) gene polymorphism and attention deficit hyperactivity disorder (ADHD) in an Irish sample

2000 • 62 citations

A morphometric evidence for a hyperfunctioning mesolimbic system in an animal model of ADHD

2002 • 56 citations

No association between low- and high-activity catecholamine-methyl-transferase (COMT) and attention deficit hyperactivity disorder (ADHD) in a sample of Turkish children

2000 • 44 citations

Failure to replicate an association between the catechol-O-methyltransferase polymorphism and attention deficit hyperactivity disorder in a second, independently recruited Israeli cohort

2000 • 42 citations

[Association analysis between attention-deficit hyperactivity disorder and Val158Met polymorphism of catechol-O-methyltransferase gene].

2003 • 12 citations