Fluorescence Changes of Genetic Calcium Indicators and OGB-1 Correlated with Neural Activity and CalciumIn VivoandIn Vitro

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

Two-Photon Laser Scanning Fluorescence Microscopy

1990 • 9,129 citations

THE GREEN FLUORESCENT PROTEIN

1998 • 5,991 citations

Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin

1997 • 3,163 citations

Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins

1998 • 2,538 citations

Transposition of Cloned P Elements into Drosophila Germ Line Chromosomes

1982 • 1,560 citations

A high signal-to-noise Ca2+ probe composed of a single green fluorescent protein

2001 • 1,499 citations

Reducing the Environmental Sensitivity of Yellow Fluorescent Protein

2001 • 1,013 citations

Expanded dynamic range of fluorescent indicators for Ca ²⁺ by circularly permuted yellow fluorescent proteins

2004 • 1,009 citations

Quantitative Ultrastructural Analysis of Hippocampal Excitatory Synapses

1997 • 973 citations

Two-Photon Calcium Imaging Reveals an Odor-Evoked Map of Activity in the Fly Brain

2003 • 814 citations

Ectopic and increased expression of fasciclin II alters motoneuron growth cone guidance

1994 • 690 citations

Conditioned Behavior in Drosophila melanogaster

1974 • 644 citations

Ca2+ buffering and action potential-evoked Ca2+ signaling in dendrites of pyramidal neurons

1996 • 563 citations

A single population of olfactory sensory neurons mediates an innate avoidance behaviour in Drosophila

2004 • 535 citations

Photobleaching in Two-Photon Excitation Microscopy

2000 • 510 citations

Ca2+ Indicators Based on Computationally Redesigned Calmodulin-Peptide Pairs

2006 • 495 citations

Transmission of Olfactory Information between Three Populations of Neurons in the Antennal Lobe of the Fly

2002 • 474 citations

Imaging cellular signals in the heart in vivo : Cardiac expression of the high-signal Ca ²⁺ indicator GCaMP2

2006 • 430 citations

A Genetically Encoded Optical Probe of Membrane Voltage

1997 • 424 citations

The role of calmodulin as a signal integrator for synaptic plasticity

2005 • 418 citations

Estimating Intracellular Calcium Concentrations and Buffering without Wavelength Ratioing

2000 • 412 citations

A comparison of fluorescent Ca2+indicator properties and their use in measuring elementary and global Ca2+signals

2000 • 381 citations

Imaging Taste Responses in the Fly Brain Reveals a Functional Map of Taste Category and Behavior

2006 • 379 citations

In Vivo Imaging of Neuronal Activity by Targeted Expression of a Genetically Encoded Probe in the Mouse

2004 • 365 citations

Excitatory Local Circuits and Their Implications for Olfactory Processing in the Fly Antennal Lobe

2007 • 356 citations

Presynaptic calcium and control of vesicle fusion

2005 • 337 citations

A FRET-Based Calcium Biosensor with Fast Signal Kinetics and High Fluorescence Change

2005 • 303 citations

Calcium dynamics associated with a single action potential in a CNS presynaptic terminal

1997 • 298 citations

In Vivo Imaging of C. elegans Mechanosensory Neurons Demonstrates a Specific Role for the MEC-4 Channel in the Process of Gentle Touch Sensation

2003 • 293 citations

Imaging Calcium Concentration Dynamics in Small Neuronal Compartments

2004 • 284 citations

Imaging Neuronal Activity During Zebrafish Behavior With a Genetically Encoded Calcium Indicator

2003 • 260 citations

Genetically Encoded Indicators of Cellular Calcium Dynamics Based on Troponin C and Green Fluorescent Protein

2004 • 250 citations

Functional Fluorescent Ca2+ Indicator Proteins in Transgenic Mice under TET Control

2004 • 243 citations

Spatial profile of dendritic calcium transients evoked by action potentials in rat neocortical pyramidal neurones.

1995 • 229 citations

Single-Cell Analysis of Drosophila Larval Neuromuscular Synapses

2001 • 228 citations

Design and characterization of a DNA‐encoded, voltage‐sensitive fluorescent protein

2001 • 225 citations

Monitoring Neural Activity and [Ca²⁺] with Genetically Encoded Ca²⁺Indicators

2004 • 223 citations

Genetically Expressed Cameleon in Drosophila melanogaster Is Used to Visualize Olfactory Information in Projection Neurons

2002 • 222 citations

Targeted Whole-Cell Recordings in the Mammalian Brain In Vivo

2003 • 221 citations

A quantitative analysis of presynaptic calcium dynamics that contribute to short-term enhancement

1995 • 205 citations

In VivoPerformance of Genetically Encoded Indicators of Neural Activity in Flies

2005 • 201 citations

Response Properties of Motion-Sensitive Visual Interneurons in the Lobula Plate of Drosophila melanogaster

2008 • 200 citations

Functional Stoichiometry and Local Enrichment of Calmodulin Interacting with Ca ²⁺ Channels

2004 • 196 citations

Single-spike detection in vitro and in vivo with a genetic Ca2+ sensor

2008 • 196 citations

Stereotyped Odor-Evoked Activity in the Mushroom Body ofDrosophilaRevealed by Green Fluorescent Protein-Based Ca²⁺Imaging

2004 • 192 citations

Improved calcium imaging in transgenic mice expressing a troponin C–based biosensor

2007 • 189 citations

A Genetically Targetable Fluorescent Probe of Channel Gating with Rapid Kinetics

2002 • 187 citations

T-jump study of calcium binding kinetics of calcium chelators

1997 • 186 citations

Innovations in the Imaging of Brain Functions using Fluorescent Proteins

2005 • 160 citations

Characterization and Subcellular Targeting of GCaMP-Type Genetically-Encoded Calcium Indicators

2008 • 154 citations

Fast Calcium Signals inDrosophilaMotor Neuron Terminals

2002 • 153 citations

OPTICAL IMAGING AND CONTROL OF GENETICALLY DESIGNATED NEURONS IN FUNCTIONING CIRCUITS

2005 • 136 citations

Genetically Encoded Bright Ca²⁺ Probe Applicable for Dynamic Ca²⁺ Imaging of Dendritic Spines

2005 • 129 citations

Heterogeneity in synaptic transmission along a Drosophila larval motor axon

2005 • 128 citations

Functional organization of sensory input to the olfactory bulb glomerulus analyzed by two-photon calcium imaging

2004 • 111 citations

Temporal Activity Patterns in Thermosensory Neurons of Freely Moving Caenorhabditis elegans Encode Spatial Thermal Gradients

2007 • 110 citations

Activation of cerebellar parallel fibers monitored in transgenic mice expressing a fluorescent Ca²⁺ indicator protein

2005 • 104 citations

Tuning FlaSh: Redesign of the Dynamics, Voltage Range, and Color of the Genetically Encoded Optical Sensor of Membrane Potential

2002 • 97 citations

Differential regulation of active zone density during long-term strengthening of Drosophila neuromuscular junctions.

2002 • 93 citations

Differential Regulation of Active Zone Density during Long-Term Strengthening ofDrosophilaNeuromuscular Junctions

2002 • 77 citations

Ca²⁺Dynamics along Identified Synaptic Terminals inDrosophilaLarvae

2006 • 68 citations

In vivo calcium imaging from genetically specified target cells in mouse cerebellum

2006 • 67 citations

Two-photon targeted patching (TPTP) in vivo

2006 • 61 citations

Evaluating a genetically encoded optical sensor of neural activity using electrophysiology in intact adult fruit flies

2007 • 58 citations

Concatenation of Cyan and Yellow Fluorescent Proteins for Efficient Resonance Energy Transfer

2006 • 57 citations

Synaptic Vesicles: Test for a Role in Presynaptic Calcium Regulation

2004 • 54 citations

Live-Cell Transforms between Ca2+ Transients and FRET Responses for a Troponin-C-Based Ca2+ Sensor

2007 • 37 citations

From Art to Engineering? The Rise of In Vivo Mammalian Electrophysiology via Genetically Targeted Labeling and Nonlinear Imaging

2005 • 27 citations

Relating a calcium indicator signal to the unperturbed calcium concentration time-course

2007 • 20 citations