Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Crystal Structure of the Aequorea victoria Green Fluorescent Protein

1996 • 2,167 citations

Wavelength mutations and posttranslational autoxidation of green fluorescent protein.

1994 • 1,773 citations

Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer

1996 • 1,462 citations

Solution structure of a calmodulin-target peptide complex by multidimensional NMR

1992 • 1,258 citations

Structure of calmodulin refined at 2.2 Å resolution

1988 • 1,019 citations

Molecular and Structural Basis of Target Recognition by Calmodulin

1995 • 752 citations

A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells

1996 • 624 citations

Spatially and Functionally Distinct Ca ²⁺ Stores in Sarcoplasmic and Endoplasmic Reticulum

1997 • 460 citations

Vesicular stomatitis virus glycoprotein is sorted and concentrated during export from the endoplasmic reticulum

1994 • 392 citations

Detection in Living Cells of Ca2+-dependent Changes in the Fluorescence Emission of an Indicator Composed of Two Green Fluorescent Protein Variants Linked by a Calmodulin-binding Sequence

1997 • 389 citations

Molecular Tuning of Ion Binding to Calcium Signaling Proteins

1994 • 370 citations

Monitoring dynamic changes in free Ca2+ concentration in the endoplasmic reticulum of intact cells.

1995 • 308 citations

Ca2+ binding and conformational change in two series of point mutations to the individual Ca(2+)-binding sites of calmodulin.

1992 • 213 citations

What is the concentration of calcium ions in the endoplasmic reticulum?

1996 • 136 citations

Cyclic Ca2+ changes in intracellular stores of gonadotropes during gonadotropin-releasing hormone-stimulated Ca2+ oscillations.

1994 • 109 citations

Targeting aequorin to the endoplasmic reticulum of living cells

1992 • 107 citations

Nuclear targeting of aequorin

1994 • 79 citations

Quantification of intraluminal free [Ca] in the agonistmsensitive internal calcium store using compartmentalized fluorescent indicators: some considerations

1996 • 79 citations

Activation of four enzymes by two series of calmodulin mutants with point mutations in individual Ca2+ binding sites.

1993 • 69 citations

Smoothly graded Ca2+ release from inositol 1,4,5-trisphosphate-sensitive Ca2+ stores.

1994 • 63 citations

A calmodulin-target peptide hybrid molecule with unique calcium-binding properties

1994 • 62 citations

Spectroscopic Characterization of a High-Affinity Calmodulin−Target Peptide Hybrid Molecule

1996 • 40 citations

Aequorin targeted to the endoplasmic reticulum reveals heterogeneity in luminal Ca++ concentration and reports agonist- or IP3-induced release of Ca++.

1996 • 39 citations

Recombinant apoaequorin acting as a pseudo-luciferase reports micromolar changes in the endoplasmic reticulum free Ca2+ of intact cells

1996 • 34 citations

Extracellular ATP elevates cytoplasmatic free Ca2+ in HeLa cells by the interaction with a 5′-nucleotide receptor

1993 • 20 citations