The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host

PHYLIP-Phylogeny inference package (Version 3.2)

1989 • 17,674 citations

A simple method of estimating 50 per cent end points

1938 • 8,381 citations

Universal primer set for the full-length amplification of all influenza A viruses

2001 • 1,946 citations

A DNA transfection system for generation of influenza A virus from eight plasmids

2000 • 1,512 citations

Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus

1998 • 1,386 citations

Characterization of an Avian Influenza A (H5N1) Virus Isolated from a Child with a Fatal Respiratory Illness

1998 • 1,351 citations

Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia

2004 • 1,337 citations

Molecular Basis for High Virulence of Hong Kong H5N1 Influenza A Viruses

2001 • 1,288 citations

Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome

2004 • 1,080 citations

Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus

1998 • 1,047 citations

A single amino acid in the PB2 gene of influenza A virus is a determinant of host range

1993 • 891 citations

Genetic Characterization of the Pathogenic Influenza A/Goose/Guangdong/1/96 (H5N1) Virus: Similarity of Its Hemagglutinin Gene to Those of H5N1 Viruses from the 1997 Outbreaks in Hong Kong

1999 • 727 citations

Molecular characterization of H9N2 influenza viruses: Were they the donors of the “internal” genes of H5N1 viruses in Hong Kong?

1999 • 711 citations

Options for the control of influenza III

1997 • 591 citations

Influenza: old and new threats

2004 • 581 citations

Avian Influenza H5N1 in Tigers and Leopards

2004 • 487 citations

Exceptional Convergent Evolution in a Virus

1997 • 380 citations

PB2 amino acid at position 627 affects replicative efficiency, but not cell tropism, of Hong Kong H5N1 influenza A viruses in mice

2004 • 380 citations

Emergence of multiple genotypes of H5N1 avian influenza viruses in Hong Kong SAR

2002 • 374 citations

Survey of the Hemagglutinin (HA) Cleavage Site Sequence of H5 and H7 Avian Influenza Viruses: Amino Acid Sequence at the HA Cleavage Site as a Marker of Pathogenicity Potential

1996 • 338 citations

Biological Heterogeneity, Including Systemic Replication in Mice, of H5N1 Influenza A Virus Isolates from Humans in Hong Kong

1999 • 275 citations

Continuing Evolution of H9N2 Influenza Viruses in Southeastern China

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Characterization of an influenza A virus from seals

1981 • 235 citations

Characterization of the Influenza A Virus Gene Pool in Avian Species in Southern China: Was H6N1 a Derivative or a Precursor of H5N1?

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The value of a database in surveillance and vaccine selection

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Virulence-associated sequence duplication at the hemagglutinin cleavage site of avian influenza viruses

1997 • 207 citations

Evolution of the nucleoprotein gene of influenza A virus

1990 • 204 citations

Genetic analysis of the compatibility between polymerase proteins from human and avian strains of influenza A viruses

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Rapid Evolution of H5N1 Influenza Viruses in Chickens in Hong Kong

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Evolution of pig influenza viruses

1991 • 142 citations

Evolution of influenza A virus PB2 genes: implications for evolution of the ribonucleoprotein complex and origin of human influenza A virus

1990 • 108 citations

European Swine Virus as a Possible Source for the Next Influenza Pandemic?

1995 • 105 citations

Generation of seal influenza virus variants pathogenic for chickens, because of hemagglutinin cleavage site changes

1990 • 100 citations

Fine Mapping of the Subunit Binding Sites of Influenza Virus RNA Polymerase

2002 • 91 citations

Independence of Evolutionary and Mutational Rates after Transmission of Avian Influenza Viruses to Swine

1999 • 74 citations

Opinion of the Scientific Panel Animal Health and Welfare (AHAW) related with the Migratory Birds and their Possible Role in the Spread of Highly Pathogenic Avian Influenza

2006 • 66 citations

Evolutionary pathways of the PA genes of influenza a viruses

1989 • 57 citations

Pathogenicity of influenza A/Seal/Mass/1/80 virus mutants for mammalian species

1995 • 48 citations

Pathogenicity and Diagnosis of H5N2 Mexican Avian Influenza Viruses in Chickens

1997 • 35 citations

Molecular Mapping of Influenza Virus RNA Polymerase by Site-Specific Antibodies

1999 • 19 citations