Biological Heterogeneity, Including Systemic Replication in Mice, of H5N1 Influenza A Virus Isolates from Humans in Hong Kong

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

1987 • 59,130 citations

Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus

1998 • 1,386 citations

Characterization of an Avian Influenza A (H5N1) Virus Isolated from a Child with a Fatal Respiratory Illness

1998 • 1,351 citations

Optimal alignments in linear space

1988 • 1,229 citations

Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus

1998 • 1,047 citations

A single amino acid in the PB2 gene of influenza A virus is a determinant of host range

1993 • 891 citations

Activation of influenza A viruses by trypsin treatment

1975 • 831 citations

Influenza virus hemagglutinin with multibasic cleavage site is activated by furin, a subtilisin-like endoprotease.

1992 • 628 citations

Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide

1975 • 602 citations

Host cell proteases controlling virus pathogenicity

1994 • 468 citations

Comparisons of Highly Virulent H5N1 Influenza A Viruses Isolated from Humans and Chickens from Hong Kong

1998 • 347 citations

A novel mechanism for the acquisition of virulence by a human influenza A virus

1998 • 235 citations

Characterization of an influenza A virus from seals

1981 • 235 citations

Biologic importance of neuraminidase stalk length in influenza A virus

1993 • 219 citations

Proprotein-processing endoproteases PC6 and furin both activate hemagglutinin of virulent avian influenza viruses

1994 • 215 citations

Direct sequencing of the HA gene of influenza (H3N2) virus in original clinical samples reveals sequence identity with mammalian cell-grown virus

1990 • 176 citations

A STUDY OF THE NEUROTROPIC TENDENCY IN STRAINS OF THE VIRUS OF EPIDEMIC INFLUENZA

1940 • 108 citations

Evolution of influenza A virus PB2 genes: implications for evolution of the ribonucleoprotein complex and origin of human influenza A virus

1990 • 108 citations

Update: Isolation of Avian Influenza A(H5N1) Viruses From Humans—Hong Kong, 1997-1998

1998 • 103 citations

Isolation of Avian Influenza A(H5N1) Viruses From Humans—Hong Kong, May-December 1997

1998 • 96 citations

Electrophoretic analysis of iodine-labeled influenza virus RNA segments

1980 • 92 citations

The influenza virus variant A/FM/1/47-MA possesses single amino acid replacements in the hemagglutinin, controlling virulence, and in the matrix protein, controlling virulence as well as growth

1994 • 82 citations

Pathological studies of chickens experimentally infected with two highly pathogenic avian influenza viruses

1996 • 81 citations

Equine H7N7 influenza A viruses are highly pathogenic in mice without adaptation: potential use as an animal model

1991 • 49 citations

Neurovirulence of influenza A virus

1996 • 48 citations

Update: isolation of avian influenza A(H5N1) viruses from humans--Hong Kong, 1997-1998.

1998 • 29 citations