Early development of the T cell repertoire. In vivo treatment of neonatal mice with anti-Ia antibodies interferes with differentiation of I-restricted T cells but not K/D-restricted T cells.

Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition

1981 • 1,048 citations

Properties of Monoclonal Antibodies to Mouse Ig Allotypes, H-2, and Ia Antigens

1979 • 993 citations

Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens.

1980 • 850 citations

Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression.

1981 • 581 citations

Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder mice.

1978 • 353 citations

H-2 antigens of the thymus determinelymphocyte specificity

1978 • 321 citations

The lymphoreticular system in triggering virus plus self-specific cytotoxic T cells: evidence for T help.

1978 • 268 citations

In vivo effects of antibodies to immune response gene products: prevention of experimental allergic encephalitis.

1981 • 228 citations

T‐T Cell Interactions during Cytotoxic T Lymphocyte (CTL) Responses: T Cell Derived Helper Factor (Interleukin 2) as a Probe to Analyze CTL Responsiveness and Thymic Maturation of CTL Progenitors

1980 • 222 citations

Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. II. Evidence for restrictions affecting helper cell induction and T-B collaboration, both mapping to the K-end of the H-2 complex.

1978 • 185 citations

T-cell specificity for H–2 and Ir gene phenotype correlates with the phenotype of thymic antigen-presenting cells

1980 • 153 citations

The Function and Interrelationships of T‐Cell Receptors, Ir Genes and Other Histocompatibility Gene Products

1975 • 152 citations

Alloreactivity of an antigen-specific T-cell clone

1980 • 150 citations

Cell surface appearance of unexpected host MHC determinants on thymocytes from radiation bone marrow chimeras.

1981 • 135 citations

Cellular and genetic control of antibody responses. V. Helper T-cell recognition of H-2 determinants on accessory cells but not B cells.

1979 • 128 citations

Role of the Murine Major Histocompatibility Complex in the Specificity of in vitro T‐Cell‐Mediated Lympholysis Against Chemically‐Modified Autologous Lymphocytes

1976 • 97 citations

Effects of blocking helper T cell induction in vivo with anti-Ia antibodies. Possible role of I-A/E hybrid molecules as restriction elements.

1980 • 68 citations

Self recognition in allogeneic thymic chimeras. Self recognition by T helper cells from thymus-engrafted nude mice is restricted to the thymic H-2 haplotype.

1982 • 65 citations

Antigen-presenting cell function in induction of helper T cells for cytotoxic T-lymphocyte responses: evidence for antigen processing.

1981 • 62 citations

The H-2 phenotype of the thymus dictates the self-specificity expressed by thymic but not splenic cytotoxic T lymphocyte precursors in thymus-engrafted nude mice.

1981 • 61 citations

Cytotoxic T lymphocyte responses in allogeneic radiation bone marrow chimeras. The chimeric host strictly dictates the self-repertoire of Ia-restricted T cells but not H-2K/D-restricted T cells.

1982 • 58 citations

The role of H-2 and Ia antigens in graft-versus-host reactions (GVHR). Presence of host alloantigens on donor cells after GVHR and suppression of GVHR with an anti-Ia antiserum against hose Ia antigens.

1979 • 40 citations

Cell Types Required for H-2-Restricted Cytotoxic Responses Generated by Trinitrobenzene Sulfonate-Modified Syngeneic Cells or Trinitrophenyl-Conjugated Proteins

1979 • 39 citations

Major histocompatibility complex-restricted self recognition. A monoclonal anti-I-Ak reagent blocks helper T cell recognition of self major histocompatibility complex determinants.

1980 • 37 citations

A Cardinal Role for I‐Region Antigens (Ia) in Immunological Enhancement, and the Clinical Implications

1976 • 36 citations

Role of syngeneic Ia+ accessory cells in the generation of allospecific CTL responses.

1982 • 36 citations

Potentiation of a primary in vivo antibody response by alloantisera against gene products of the I region of the H-2 complex.

1977 • 34 citations

Regulation of immune response to tumor antigen: interference with syngeneic tumor immunity by anti-IA alloantisera.

1979 • 33 citations

Adaptive differentiation of murine lymphocytes. II. The thymic microenvironment does not restrict the cooperative partner cell preference of helper T cells differentiating in F1 leads to F1 thymic chimeras.

1979 • 33 citations

Expression of both I-A and I-E/C subregion antigens on accessory cells required for in vitro generation of cytotoxic T lymphocytes against alloantigens or TNBS-modified syngeneic cells.

1980 • 32 citations

Cytotoxic T lymphocyte responses by chimeric thymocytes. Self-recognition is determined early in T cell development.

1981 • 29 citations

In vivo or in vitro treatments with anti-I-J alloantisera abolish immunity to AKR leukemia.

1980 • 29 citations

Development and Loss of Virus‐Specific Thymic Competence in Bone Marrow Radiation Chimeras and Normal Mice

1981 • 27 citations

Neonatal suppression with anti-Ia antibody. I. Suppression of murine B lymphocyte development.

1982 • 23 citations

Analysis of H-2 determinants recognized during the induction of H-Y-immune cytotoxic T cells by monoclonal antibodies in vitro

1981 • 21 citations

I region‐restricted T cell line stimulated with haptentreated syngeneic cells: Selection of clones with reactivity for both allogeneic Ia determinants and self‐I‐A plus hapten

1982 • 18 citations

The role of the left end of the H‐2^b haplotype in the male‐specific cytotoxic T cell response

1979 • 15 citations