Alloreactivity of an antigen-specific T-cell clone

The somatic generation of immune recognition

1971 • 974 citations

The H-2 Major Histocompatibility Complex and the/Immune Response Region: Genetic Variation, Function, and Organization

1975 • 774 citations

Progress in immunology

1968 • 577 citations

Continuous proliferation of murine antigen-specific helper T lymphocytes in culture.

1979 • 522 citations

Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder mice.

1978 • 353 citations

Fine specificity of a continuously growing killer cell clone specific for H-Y antigen

1979 • 317 citations

Two Different V_H Gene Products Make Up the T‐Cell Receptors

1976 • 179 citations

Killer cells reactive to altered-self antigens can also be alloreactive.

1977 • 155 citations

The Clonal Selection Hypothesis Evaluated by Grafted Cells Reacting Against their Hosts

1967 • 121 citations

Cell-mediated immunity and the major histocompatibility complex

1978 • 119 citations

Cytolytic thymus-derived lymphocytes specific for allogeneic stimulator cells crossreact with chemically modified syngeneic cells.

1977 • 118 citations

Direct cloning and extended culture of antigen-specific MHC-restricted, proliferating T lymphocytes

1980 • 115 citations

The Effect of T Cell Growth Factor on the Generation of Cytolytic T Cells

1978 • 113 citations

In vitro growth of murine T cells. I. Production of factors necessary for T cell growth.

1978 • 110 citations

The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens

1978 • 101 citations

Clonal Induction of Helper T Cells: Conversion of Specific Signals into Nonspecific Signals

1980 • 97 citations

T-cell inhibition of humoral responsiveness

1978 • 86 citations

A Dual Recognition Model for Cytotoxic T Cells Based on Thymic Selection of Precursors with Low Affinity for Self H‐2 Antigens

1978 • 77 citations

Sheep red blood cell-specific helper activity in rat thoracic duct lymphocyte populations positively selected for reactivity to specific strong histocompatibility alloantigens.

1976 • 45 citations

In Vitro Growth of Murine T Cells

1978 • 30 citations

Fine Specificity and Cytolytic Activity of Continuously Growing Alloreactive Cytotoxic T Lymphocyte Clones

1980 • 17 citations