CXC-chemokines, a new group of cytokines in congestive heart failure — possible role of platelets and monocytes

Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure

1990 • 2,566 citations

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.

1994 • 2,251 citations

Negative Inotropic Effects of Cytokines on the Heart Mediated by Nitric Oxide

1992 • 1,635 citations

Endotoxin and immune activation in chronic heart failure: a prospective cohort study

1999 • 851 citations

Pathophysiologically Relevant Concentrations of Tumor Necrosis Factor-α Promote Progressive Left Ventricular Dysfunction and Remodeling in Rats

1998 • 810 citations

Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death.

1996 • 742 citations

Cellular basis for the negative inotropic effects of tumor necrosis factor-alpha in the adult mammalian heart.

1993 • 708 citations

Activated platelets signal chemokine synthesis by human monocytes.

1996 • 598 citations

In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function.

1996 • 552 citations

A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice.

1998 • 525 citations

Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice.

1995 • 504 citations

Mechanisms of neutrophil-induced parenchymal cell injury

1997 • 446 citations

Elevated soluble CD14 receptors and altered cytokines in chronic heart failure

1997 • 393 citations

Induction of Cytokine Expression in Leukocytes by Binding of Thrombin-Stimulated Platelets

1997 • 385 citations

Basic Mechanisms in Congestive Heart Failure

1994 • 365 citations

Elevated Circulating Levels of C-C Chemokines in Patients With Congestive Heart Failure

1998 • 357 citations

Chemokines, inflammation and the immune system.

1994 • 302 citations

Effect of Human Recombinant Interleukin-6 and Interleukin-8 on Monocyte Procoagulant Activity

1997 • 288 citations

T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo.

1996 • 271 citations

Upregulation of cell adhesion molecules and the presence of low grade inflammation in human chronic heart failure

1997 • 268 citations

Nuclear factor-kappa B potently up-regulates the promoter activity of RANTES, a chemokine that blocks HIV infection.

1997 • 238 citations

Oxygen Free Radicals and Platelet Activation

1997 • 236 citations

Platelet function, thrombin and fibrinolytic activity in patients with heart failure

1993 • 222 citations

Activation of JAK-STAT and MAP Kinases by Leukemia Inhibitory Factor Through gp130 in Cardiac Myocytes

1996 • 192 citations

Systemic inflammation in patients with heart failure

1998 • 182 citations

Increased Expression of Interleukin-1β and Monocyte Chemotactic and Activating Factor/Monocyte Chemoattractant Protein-1 in the Hypertrophied and Failing Heart With Pressure Overload

1997 • 163 citations

Synergism Between Platelets and Neutrophils in Provoking Cardiac Dysfunction After Ischemia and Reperfusion

1998 • 157 citations

Enhanced activation of platelets with abnormal release of RANTES in human immunodeficiency virus type 1 infection

1998 • 148 citations

[Ca2+]i Changes and Respiratory Burst in Human Neutrophils and Monocytes Induced by NAP-1/Interleukin-8, NAP-2, and gro/MGSA

1991 • 123 citations

G protein-mediated suppression of L-type Ca2+ current by interleukin-1 beta in cultured rat ventricular myocytes

1995 • 118 citations

Chemokine and chemokine receptor mRNA expression in human platelets

1995 • 114 citations

Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo.

1998 • 114 citations

Circulatory Resuscitation With Left Ventricular Assist Device Support Reduces Interleukins 6 and 8 Levels

1997 • 87 citations

Role of early reperfusion in the induction of adhesion molecules and cytokines in previously ischemic myocardium

1995 • 65 citations

Monocyte activation in congestive heart failure due to coronary artery disease and idiopathic dilated cardiomyopathy

1998 • 64 citations

Differential Modulation of Cytokine Production by Drugs: Implications for Therapy in Heart Failure

1996 • 56 citations

Expression of leukocyte chemotactic cytokines in myocardial tissue

1995 • 43 citations

Oxidative Metabolism of Polymorphonuclear Leukocytes: Modulation by Adhesive Stimuli

1991 • 41 citations

Impaired platelet function correlates with multi-organ dysfunction. A study of patients with sepsis

1998 • 31 citations

Rapid secretion of intracellularly pre-stored interleukin-8 from rabbit platelets upon activation

1996 • 30 citations

Impairedin vitrosurvival of monocytes from patients with HIV infection

1990 • 27 citations

Tumor necrosis factor alpha and cardiac remodeling

1995 • 11 citations