High-Dose/Activation-Associated Tolerance

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1993 • 1,219 citations

Cell migration, chimerism, and graft acceptance

1992 • 1,075 citations

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

Induction of Immunological Tolerance by Porcine Liver Allografts

1969 • 826 citations

Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells.

1982 • 807 citations

Cell migration and chimerism after whole-organ transplantation: The basis of graft acceptance

1993 • 795 citations

Peripheral Selection of the T Cell Repertoire

1991 • 666 citations

The behaviour and fate of skin autografts and skin homografts in rabbits: A report to the War Wounds Committee of the Medical Research Council.

1944 • 661 citations

Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection.

1990 • 561 citations

T Cell Deletion in High Antigen Dose Therapy of Autoimmune Encephalomyelitis

1994 • 530 citations

Immunobiology of Tissue Transplantation: A Return to the Passenger Leukocyte Concept

1983 • 524 citations

Murine liver allograft transplantation: Tolerance and donor cell chimerism

1994 • 459 citations

Immunological enhancement of tumor homografts in mice: a review.

1958 • 346 citations

Bone marrow augmentation of donor-cell chimerism in kidney, liver, heart, and pancreas islet transplantation

1994 • 309 citations

Specific unresponsiveness in rats with prolonged cardiac allograft survival after treatment with cyclosporine. III. Further characterization of the CD4+ suppressor cell and its mechanisms of action.

1990 • 302 citations

Presence of hematopoietic stem cells in the adult liver

1996 • 300 citations

HEART ALLOGRAFTS IN MURINE SYSTEMS

1992 • 299 citations

Reversal of transplantation immunity by liver grafting

1981 • 278 citations

Soluble HLA class I molecules induce apoptosis in alloreactive cytotoxic T lymphocytes

1996 • 274 citations

Cytokine gene transcription in vascularised organ grafts: analysis using semiquantitative polymerase chain reaction.

1991 • 267 citations

Donor cell chimerism permitted by immunosuppressive drugs: a new view of organ transplantation

1993 • 251 citations

Propagation of dendritic cell progenitors from normal mouse liver using granulocyte/macrophage colony-stimulating factor and their maturational development in the presence of type-1 collagen.

1994 • 247 citations

SOLUBLE HLA ANTIGENS IN THE CIRCULATION OF LIVER GRAFT RECIPIENTS

1989 • 239 citations

Weaning Of Immunosuppression In Long-Term Liver Transplant Recipients

1995 • 234 citations

Induction of nitric oxide synthase in mouse dendritic cells by IFN-gamma, endotoxin, and interaction with allogeneic T cells: nitric oxide production is associated with dendritic cell apoptosis.

1996 • 210 citations

Granulocyte/macrophage colony-stimulating factor-stimulated hepatic dendritic cell progenitors prolong pancreatic islet allograft survival.

1995 • 202 citations

The immunology of experimental liver transplantation in the rat.

1985 • 200 citations

Growth of donor-derived dendritic cells from the bone marrow of murine liver allograft recipients in response to granulocyte/macrophage colony-stimulating factor.

1995 • 185 citations

TOLERANCE TO RAT LIVER ALLOGRAFTS

1996 • 180 citations

FULLY ALLOGENEIC LIVER GRAFTING IN RATS INDUCES A STATE OF SYSTEMIC NONREACTIVITY TO DONOR TRANSPLANTATION ANTIGENS

1980 • 177 citations

DELETION OF SPONTANEOUS RAT LIVER ALLOGRAFT ACCEPTANCE BY DONOR IRRADIATION

1995 • 173 citations

Tolerance to rat liver allografts. III. Donor cell migration and tolerance-associated cytokine production in peripheral lymphoid tissues.

1996 • 142 citations

SPECIFIC SUPPRESSION OF ALLOGRAFT REJECTION BY SOLUBLE CLASS I ANTIGEN AND COMPLEXES WITH MONOCLONAL ANTIBODY

1990 • 138 citations

The essential roles of parenchymal tissues and passenger leukocytes in the tolerance induced by liver grafting in rats

1995 • 138 citations

The dosage requirements for immunological paralysis by soluble proteins.

1968 • 137 citations

HIGH-DOSE DONOR BONE MARROW INFUSIONS TO ENHANCE ALLOGRAFT SURVIVAL

1997 • 136 citations

Rejection of Renal Allografts: Specific Immunologic Suppression

1968 • 132 citations

PERIPHERAL TOLERANCE OF AN ALLOGRAFT IN ADULT RATS—CHARACTERIZATION BY LOW INTERLEUKIN-2 AND INTERFERON-γ mRNA LEVELS AND BY STRONG ACCUMULATION OF MAJOR HISTOCOMPATIBILITY COMPLEX TRANSCRIPTS IN THE GRAFT

1992 • 117 citations

Early events in liver allograft rejection. Delineation of sites of simultaneous intragraft and recipient lymphoid tissue sensitization.

1991 • 101 citations

SUPPRESSOR T CELLS IN ALLOGENEIC MODELS

1986 • 94 citations

THE EFFECT OF DONOR PRETREATMENT ON INTERSTITIAL DENDRITIC CELL CONTENT AND RAT CARDIAC ALLOGRAFT SURVIVAL

1984 • 84 citations

LUNG ALLOGRAFT REJECTION IN THE RAT

1985 • 74 citations

Tolerance to rat liver allografts. I. Differences between tolerance and rejection are more marked in the B cell compared with the T cell or cytokine response.

1994 • 72 citations

T cell anergy

1994 • 63 citations

IN VITRO PROPAGATION AND HOMING OF LIVER-DERIVED DENDRITIC CELL PROGENITORS TO LYMPHOID TISSUES OF ALLOGENEIC RECIPIENTS

1995 • 59 citations

Clonal deletion as the mechanism of abrogation of immunological memory following liver grafting in rats.

1985 • 57 citations

TOLERANCE TO RAT LIVER ALLOGRAFTS

1994 • 55 citations

Specific Inhibition of Antibody Formation During Immunological Paralysis and Unresponsiveness

1959 • 50 citations

REJECTION OF SPONTANEOUSLY ACCEPTED RAT LIVER ALLOGRAFTS WITH RECIPIENT INTERLEUKIN-2 TREATMENT OR DONOR IRRADIATION1,2

1997 • 49 citations

Impact of donor MHC class I or class II antigen deficiency on first‐ and second‐set rejection of mouse heart or liver allografts

1996 • 46 citations

Restoration of tolerance to rat hepatic allografts by spleen-derived passenger leukocytes

1996 • 46 citations

THE ROLE OF T SUPPRESSOR CELLS IN THE MAINTENANCE OF SPONTANEOUSLY ACCEPTED ORTHOTOPIC RAT LIVER ALLOGRAFTS

1992 • 43 citations

PREVENTION OF ORTHOTOPIC LIVER ALLOGRAFT REJECTION IN RATS WITH A SHORT-TERM BREQUINAR SODIUM THERAPY

1994 • 41 citations

A DETAILED ANALYSIS OF THE POTENTIAL OF WATER-SOLUBLE CLASSICAL CLASS I MHC MOLECULES FOR THE SUPPRESSION OF KIDNEY ALLOGRAFT REJECTION AND IN VITRO CYTOTOXIC T CELL RESPONSES

1989 • 41 citations

Physiological T‐Cell Death: Susceptibility is Modulated by Activation, Aging, and Transformation, but the Mechanism is Constant

1994 • 39 citations

Antigen-Induced Programmed T Cell Death as a New Approach to Immune Therapy

1995 • 39 citations

Delayed rejection of renal allografts in the rat and dog by reduction of passenger leukocytes.

1971 • 37 citations

ACUTE LIVER ALLOGRAFT REJECTION IN THE RAT

1995 • 36 citations

Restoration of tolerance to rat hepatic allografts by spleen-derived passenger leukocytes

1996 • 35 citations

Migration of donor cells into the thymus is not essential for induction and maintenance of systemic tolerance after liver transplantation in the rat.

1995 • 31 citations

Interleukin-2 and interleukin-12 mediate distinct effector mechanisms of liver allograft rejection

1997 • 26 citations

Detection of membrane-bound and soluble MHC class I antigen from donor migrating cells following rat liver transplantation

1994 • 20 citations

Weak Histocompatibility Genes: The Effect of Dose and Pretreatment of Immunizing Cells

1962 • 15 citations

Donor Leukocyte Migration Following Extremity Transplantation in an Experimental Model

1992 • 13 citations

ABROGATION OF THE IMMUNOSUPPRESSIVE EFFECT OF DONOR SPLEEN CELLS ON RENAL ALLOGRAFTS IN THE RAT BY IRRADIATION OR HEAT TREATMENT

1986 • 12 citations

Quantity of donor tissue and rat allograft survival

1997 • 9 citations