Modular organization of carbohydrate recognition domains in animal lectins

The Biogenesis of Lysosomes

1989 • 1,583 citations

Galectins. Structure and function of a large family of animal lectins.

1994 • 1,487 citations

Two distinct classes of carbohydrate-recognition domains in animal lectins.

1988 • 1,259 citations

STRUCTURAL BASIS OF LECTIN-CARBOHYDRATE RECOGNITION

1996 • 1,074 citations

Structure of a C-type mannose-binding protein complexed with an oligosaccharide

1992 • 873 citations

Biology of Animal Lectins

1993 • 752 citations

Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function

1996 • 639 citations

The family of metazoan metal-independent β-galactoside-binding lectins: structure, function and molecular evolution

1993 • 504 citations

Engineering galactose-binding activity into a C-type mannose-binding protein

1992 • 470 citations

Structure of pentameric human serum amyloid P component

1994 • 459 citations

Expression and function of galectin-3, a beta-galactoside-binding lectin, in human monocytes and macrophages.

1995 • 392 citations

Trimeric structure of a C-type mannose-binding protein

1994 • 312 citations

Endogenous galactoside-binding lectins: a new class of functional tumor cell surface molecules related to metastasis

1987 • 307 citations

Specificity of binding of three soluble rat lung lectins to substituted and unsubstituted mammalian beta-galactosides.

1986 • 299 citations

Lectin-carbohydrate complexes of plants and animals: an atomic view

1993 • 280 citations

Binding specificity of a baby hamster kidney lectin for H type I and II chains, polylactosamine glycans, and appropriately glycosylated forms of laminin and fibronectin.

1992 • 274 citations

Transient, lectin-like association of calreticulin with folding intermediates of cellular and viral glycoproteins.

1995 • 274 citations

Structure of S-lectin, a developmentally regulatedvertebrate beta-galactoside-binding protein.

1994 • 269 citations

X-ray crystal structure of the human dimeric S-Lac lectin, L-14-II, in complex with lactose at 2.9-A resolution.

1993 • 267 citations

Carbohydrates as antigenic determinants of glycoproteins

1987 • 266 citations

Biochemical and biophysical characterization of human recombinant IgE-binding protein, an S-type animal lectin.

1992 • 264 citations

L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity

1993 • 263 citations

X-ray crystal structure of the human dimeric S-Lac lectin, L-14-II, in complex with lactose at 2.9-A resolution.

1993 • 245 citations

Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple α-helical coiled-coil

1994 • 244 citations

A novel glycosaminoglycan attachment domain identified in two alternative splice variants of human versican

1994 • 243 citations

Identification of an autocrine negative growth factor: Mouse β-galactoside-binding protein is a cytostatic factor and cell growth regulator

1991 • 239 citations

Endogenous muscle lectin inhibits myoblast adhesion to laminin.

1991 • 224 citations

Crosslinking of mammalian lectin (galectin-1) by complex biantennary saccharides

1994 • 213 citations

Recombinant human β-galactoside binding lectin suppresses clinical and histological signs of experimental autoimmune encephalomyelitis

1990 • 203 citations

Collectins — soluble proteins containing collagenous regions and lectin domains — and their roles in innate immunity

1994 • 200 citations

Effect of amino acid substitution by sited-directed mutagenesis on the carbohydrate recognition and stability of human 14-kDa beta-galactoside-binding lectin.

1991 • 187 citations

Soluble lactose-binding lectin from rat intestine with two different carbohydrate-binding domains in the same peptide chain.

1993 • 179 citations

.epsilon.BP, a .beta.-galactoside-binding animal lectin, recognizes IgE receptor (Fc.epsilon.RI) and activates mast cells

1993 • 169 citations

Galectin-8

1995 • 169 citations

Cell Surface Calreticulin Is a Putative Mannoside Lectin Which Triggers Mouse Melanoma Cell Spreading

1995 • 160 citations

Selective modulation of the interaction of α7β1 integrin with fibronectin and laminin by l-14 lectin during skeletal muscle differentiation

1994 • 156 citations

Characterization of the complete genomic structure of the human versican gene and functional analysis of its promoter

1994 • 154 citations

L-14 Lectin Recognition of Laminin and Its Promotion of in Vitro Cell Adhesion

1993 • 153 citations

Crystal structure of human Charcot–Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins

1995 • 152 citations

Cloning, Expression, and Chromosome Mapping of Human Galectin-7

1995 • 146 citations

Rat olfactory neurons can utilize the endogenous lectin, L-14, in a novel adhesion mechanism

1994 • 145 citations

Interaction of human lung surfactant proteins A and D with mite (Dermatophagoides pteronyssinus) allergens

1996 • 136 citations

Molecular cloning and characterization of human eosinophil Charcot-Leyden crystal protein (lysophospholipase). Similarities to IgE binding proteins and the S-type animal lectin superfamily.

1993 • 131 citations

A parallel three stranded α‐helical bundle at the nucleation site of collagen triple‐helix formation

1994 • 122 citations

S-type mammalian lectins in allergic inflammation

1993 • 115 citations

The S-type lectin from calf heart tissue binds selectively to the carbohydrate chains of laminin

1990 • 115 citations

Physical characterization and crystallization of the carbohydrate-recognition domain of a mannose-binding protein from rat.

1991 • 111 citations

Sequence and Mapping of Galectin-5, a β-Galactoside-binding Lectin, Found in Rat Erythrocytes

1995 • 109 citations

The α-helical neck region of human lung surfactant protein D is essential for the binding of the carbohydrate recognition domains to lipopolysaccharides and phospholipids

1996 • 105 citations

Genomic sequence and organization of two members of a human lectin gene family

1991 • 97 citations

The bovine mannose 6-phosphate/insulin-like growth factor II receptor. Localization of mannose 6-phosphate binding sites to domains 1-3 and 7-11 of the extracytoplasmic region.

1991 • 86 citations

Chimeras of surfactant proteins A and D identify the carbohydrate recognition domains as essential for phospholipid interaction.

1994 • 84 citations

Soluble 14-kDa beta-galactoside-specific bovine lectin. Evidence from mutagenesis and proteolysis that almost the complete polypeptide chain is necessary for integrity of the carbohydrate recognition domain.

1991 • 79 citations

Release of calreticulin from neutrophils may alter C1q-mediated immune functions

1997 • 77 citations

LAMP-1 in cho cells is a primary carrier of poly-N-acetyllactosamine chains and is bound preferentially by a mammalian S-type lectin

1990 • 73 citations

Conformational changes in the chicken receptor for endocytosis of glycoproteins. Modulation of ligand-binding activity by Ca2+ and pH.

1988 • 70 citations

Nuclear and cytoplasmic localization of a lectin-ribonucleoprotein complex

1992 • 59 citations

Possible interaction between animal lectins and bacterial carbohydrates

1994 • 57 citations

Further evidence by site-directed mutagenesis that conserved hydrophilic residues form a carbohydrate-binding site of human galectin-1

1994 • 49 citations

Identification of a 14-kDa laminin binding protein (HLBP14) in human melanoma cells that is identical to the 14-kDa galactoside binding lectin

1992 • 42 citations

Synthesis of a truncated Mr 46,000 mannose 6-phosphate receptor that is secreted and retains ligand binding

1989 • 37 citations

Genomic cloning of the gene for an IgE-binding lectin reveals unusual utilization of 5' untranslated regions

1992 • 33 citations

Structure of the murine Mac-2 gene. Splice variants encode proteins lacking functional signal peptides

1993 • 29 citations

A recombinant polypeptide, composed of the α‐helical neck region and the carbohydrate recogniton domain of conglutinin, self‐associates to give a functionally intact homotrimer

1995 • 20 citations

The sugared path to a normal lung: soluble beta-galactoside-specific lectins

1991 • 6 citations