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Amplification of cortical serotonin release: a further neurochemical action of the vigilance-promoting drug modafinil

Data up to Jan 2025

Published2000
Citations91
References43

Total Citations Per Year

Abstract

References (43)

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

The role of monoamines and acetylcholine-containing neurons in the regulation of the sleep-waking cycle

1972 • 1,091 citations

Effects of a new type of 5-HT receptor agonist on male rat sexual behavior

1981 • 327 citations

5‐HT1 agonists reduce 5‐hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis

1989 • 322 citations

Neurobiology of an anorectic drug: Fenfluramine

1986 • 319 citations

Modafinil Binds to the Dopamine Uptake Carrier Site with Low Affinity

1994 • 317 citations

The 5-HT1A receptor agonist, 8-OH-DPAT, preferentially activates cell body 5-HT autoreceptors in rat brain in vivo

1988 • 296 citations

Successful treatment of idiopathic hypersomnia and narcolepsy with modafinil

1988 • 271 citations

Central α1-adrenergic stimulation in relation to the behaviour stimulating effect of modafinil; studies with experimental animals

1990 • 221 citations

The substituted amphetamines 3,4-methylenedioxymethamphetamine, methamphetamine, p-chloroamphetamine and fenfluramine induce 5-hydroxytryptamine release via a common mechanism blocked by fluoxetine and cocaine

1992 • 209 citations

Modafinil induces wakefulness without intensifying motor activity or subsequent rebound hypersomnolence in the rat.

1997 • 170 citations

A Critical Review of 5-HT Brain Microdialysis and Behavior

1997 • 169 citations

Noradrenaline inhibition of acetylcholine release from guinea-pig brain

1978 • 168 citations

On-line detection of extracellular levels of serotonin in dorsal raphe nucleus and frontal cortex over the sleep/wake cycle in the freely moving rat

1998 • 164 citations

Serotonin-receptor-mediated modulation of Ca2+-dependent 5-hydroxytryptamine release from neurones of the rat brain cortex

1980 • 149 citations

Alpha-adrenoceptor-mediated modulation of 5-hydroxytryptamine release from rat brain cortex slices

1980 • 121 citations

The effects of modafinil on striatal, pallidal and nigral GABA and glutamate release in the conscious rat: evidence for a preferential inhibition of striato-pallidal GABA transmission

1998 • 119 citations

The vigilance promoting drug modafinil decreases GABA release in the medial preoptic area and in the posterior hypothalamus of the awake rat: possible involvement of the serotonergic 5-HT3 receptor

1996 • 106 citations

p-Chloroamphetamine induces serotonin release through serotonin transporters

1992 • 103 citations

The effect of the selective 5‐HT1A agonists alnespirone (S‐20499) and 8‐OH‐DPAT on extracellular 5‐hydroxytryptamine in different regions of rat brain

1997 • 103 citations

A comparison of the effects on central 5‐HT function of sibutramine hydrochloride and other weight‐modifying agents

1998 • 101 citations

Effects of Modafinil on Symptomatology of Human Narcolepsy

1993 • 94 citations

Inhibitory effects of the psychoactive drug modafinil on ?-aminobutyric acid outflow from the cerebral cortex of the awake freely moving guinea-pig

1992 • 81 citations

The presence of a serotonin uptake inhibitor alters pharmacological manipulations of serotonin release

1993 • 79 citations

Blockade of the serotonin and norepinephrine uptake processes by duloxetine: in vitro and in vivo studies in the rat brain.

1996 • 76 citations

Releasing activities of d-fenfluramine and fluoxetine and fluoxetine on rat hippocampal synaptosomes preloaded with [3H]serotonin

1992 • 75 citations

Evidence of the existence of two different intraneuronal pools from which pharmacological agents can release serotonin

1981 • 71 citations

Serotonin Receptors and Their Function in Sleep, Anxiety Disorders and Depression

1996 • 71 citations

Awakening properties of modafinil without paradoxical sleep rebound: comparative study with amphetamine in the rat

1995 • 69 citations

5‐HT4 receptor‐mediated modulation of 5‐HT release in the rat hippocampus in vivo

1996 • 68 citations

Modafinil and cortical γ-aminobutyric acid outflow. Modulation by 5-hydroxytryptamine neurotoxins

1995 • 68 citations

Different approaches to study acetylcholine release: endogenous ACh versus tritium efflux

1984 • 66 citations

Inhibitory effect of nociceptin on [3H]‐5‐HT release from rat cerebral cortex slices

1999 • 62 citations

R(+)-8-OH-DPAT, a 5-HT1A receptor agonist, inhibits amphetamine-induced serotonin and dopamine release in rat medial prefrontal cortex

1996 • 55 citations

The role of 5-HT1B/1D receptors in the modulation of 5-hydroxytryptamine levels in the frontal cortex of the conscious guinea pig

1997 • 53 citations

Lack of pre-synaptic dopaminergic involvement in modafinil activity in anaesthetized mice: In vivo voltammetry studies

1994 • 50 citations

Induction of 5-hydroxytryptamine release by tramadol, fenfluramine and reserpine

1998 • 41 citations

Effects of the vigilance promoting drug modafinil on the synthesis of GABA and glutamate in slices of rat hypothalamus

1999 • 32 citations

Paroxetine

1992 • 31 citations

Microdialysis monitoring of variations in extracellular levels of serotonin, GABA and excitatory amino acids in the frontal cortex of awake rats in response to a single peripheral or central administration of dexfenfluramine

1996 • 30 citations

PRECLINICAL STUDIES WITH MODAFINIL. EVIDENCE FOR VIGILANCE ENHANCEMENT ANDNEUROPROTECTION

1996 • 23 citations

EFFECTS OF A VIGILANCE ENHANCING DRUG, MODAFINIL, ON RAT BRAIN CORTEX AMINO ACIDS : A MICRODIALYSIS STUDY

1997 • 11 citations

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