The effects of modafinil on striatal, pallidal and nigral GABA and glutamate release in the conscious rat: evidence for a preferential inhibition of striato-pallidal GABA transmission

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Functional architecture of basal ganglia circuits: neural substrates of parallel processing

1990 • 4,029 citations

Disinhibition as a basic process in the expression of striatal functions

1990 • 848 citations

Modafinil Binds to the Dopamine Uptake Carrier Site with Low Affinity

1994 • 317 citations

A critical role of the posterior hypothalamus in the mechanisms of wakefulness determined by microinjection of muscimol in freely moving cats

1989 • 317 citations

The striopallidal neuron: a main locus for adenosine-dopamine interactions in the brain

1993 • 255 citations

Long-lasting insomnia induced by preoptic neuron lesions and its transient reversal by muscimol injection into the posterior hypothalamus in the cat

1989 • 230 citations

Central α1-adrenergic stimulation in relation to the behaviour stimulating effect of modafinil; studies with experimental animals

1990 • 221 citations

Modafinil: An antinarcoleptic drug with a different neurochemical profile to d-amphetamine and dopamine uptake blockers

1997 • 139 citations

The vigilance promoting drug modafinil increases dopamine release in the rat nucleus accumbens via the involvement of a local GABAergic mechanism

1996 • 137 citations

The antinarcoleptic drug modafinil increases glutamate release in thalamic areas and hippocampus

1997 • 110 citations

Feline subthalamic nucleus neurons contain glutamate-like but not GABA-like or glycine-like immunoreactivity

1989 • 109 citations

The vigilance promoting drug modafinil decreases GABA release in the medial preoptic area and in the posterior hypothalamus of the awake rat: possible involvement of the serotonergic 5-HT3 receptor

1996 • 106 citations

Non-amphetaminic mechanism of stimulant locomotor effect of modafinil in mice

1995 • 99 citations

Inhibitory effects of the psychoactive drug modafinil on ?-aminobutyric acid outflow from the cerebral cortex of the awake freely moving guinea-pig

1992 • 81 citations

Effect of modafinil and amphetamine on the rat catecholaminergic neuron activity

1991 • 75 citations

Non-amphetaminic mechanism of stimulant locomotor effect of modafinil in mice

1995 • 69 citations

Awakening properties of modafinil without paradoxical sleep rebound: comparative study with amphetamine in the rat

1995 • 69 citations

Evidence for a protective action of the vigilance promoting drug Modafinil on the MPTP-induced degeneration of the nigrostriatal dopamine neurons in the black mouse: an immunocytochemical and biochemical analysis

1992 • 59 citations

Lack of pre-synaptic dopaminergic involvement in modafinil activity in anaesthetized mice: In vivo voltammetry studies

1994 • 50 citations

Local preoptic/anterior hypothalamic warming alters spontaneous and evoked neuronal activity in the magno-cellular basal forebrain

1995 • 43 citations

Indirect dopamine agonists effects on despair test: Dissociation from hyperactivity

1996 • 36 citations

Modafinil-, amphetamine- and methylphenidate-induced hyperactivities in mice involve different mechanisms

1990 • 27 citations

PRECLINICAL STUDIES WITH MODAFINIL. EVIDENCE FOR VIGILANCE ENHANCEMENT ANDNEUROPROTECTION

1996 • 23 citations