Identification of double holliday junctions as intermediates in meiotic recombination

The double-strand-break repair model for recombination

1983 • 2,468 citations

DMC1: A meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression

1992 • 1,133 citations

A general model for genetic recombination.

1975 • 890 citations

DNA double-crossover molecules

1993 • 775 citations

A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae

1990 • 683 citations

Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination

1990 • 591 citations

Double-strand breaks at an initiation site for meiotic gene conversion

1989 • 533 citations

Extensive 3′-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site

1991 • 525 citations

The repair of double-strand breaks in DNA: A model involving recombination

1976 • 499 citations

Temporal comparison of recombination and synaptonemal complex formation during meiosis in S. cerevisiae

1991 • 449 citations

Meiosis-Induced Double-Strand Break Sites Determined by Yeast Chromatin Structure

1994 • 433 citations

Homothallic switching of yeast mating type cassettes is initiated by a double-stranded cut in the MAT locus

1982 • 411 citations

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.

1990 • 408 citations

Identification of joint molecules that form frequently between homologs but rarely between sister chromatids during yeast meiosis

1994 • 374 citations

Heteroduplex repair in extracts of human HeLa cells

1991 • 355 citations

Escherichia coli RuvC protein is an endonuclease that resolves the Holliday structure.

1991 • 271 citations

The kinetics of spontaneous DNA branch migration.

1994 • 264 citations

Genetic recombination: The nature of a crossed strand-exchange between two homologous DNA molecules

1972 • 237 citations

Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae.

1994 • 236 citations

Formation and resolution of recombination intermediates by E. coliRecA and RuvC proteins

1991 • 228 citations

Meiotic Gene Conversion: A Signal of the Basic Recombination Event in Yeast

1979 • 221 citations

Genetic recombination

1989 • 220 citations

Changes in chromatin structure at recombination initiation sites during yeast meiosis.

1994 • 218 citations

Mechanisms in Recombination

1974 • 204 citations

Covalent protein-DNA complexes at the 5' strand termini of meiosis-specific double-strand breaks in yeast.

1995 • 200 citations

The location and structure of double-strand DNA breaks induced during yeast meiosis: evidence for a covalently linked DNA-protein intermediate.

1995 • 169 citations

Sequence non-specific double-strand breaks and interhomolog interactions prior to double-strand break formation at a meiotic recombination hot spot in yeast.

1995 • 148 citations

Multiple sites for double-strand breaks in whole meiotic chromosomes of Saccharomyces cerevisiae.

1992 • 135 citations

Timing of molecular events in meiosis in Saccharomyces cerevisiae: stable heteroduplex DNA is formed late in meiotic prophase.

1993 • 134 citations

The nucleotide mapping of DNA double-strand breaks at the CYS3 initiation site of meiotic recombination in Saccharomyces cerevisiae.

1995 • 129 citations

Meiosis-Specific Double-Strand DNA Breaks at the HIS4 Recombination Hot Spot in the Yeast Saccharomyces cerevisiae: Control in cis and trans

1995 • 115 citations

Use of a ring chromosome and pulsed-field gels to study interhomolog recombination, double-strand DNA breaks and sister-chromatid exchange in yeast.

1989 • 113 citations

Detection of heteroduplex DNA molecules among the products of Saccharomyces cerevisiae meiosis.

1990 • 107 citations

Meiosis-specific formation of joint DNA molecules containing sequences from homologous chromosomes

1994 • 106 citations

Endonuclease VII resolves Y-junctions in branched DNA in vitro.

1986 • 104 citations

A pivotal role for the structure of the Holliday junction in DNA branch migration.

1995 • 102 citations

Crossover and noncrossover recombination during meiosis: timing and pathway relationships.

1995 • 92 citations

Physical detection of heteroduplexes during meiotic recombination in the yeast Saccharomyces cerevisiae.

1993 • 92 citations

Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break.

1993 • 88 citations

A short chromosomal region with major roles in yeast chromosome III meiotic disjunction, recombination and double strand breaks.

1993 • 79 citations

Chiasma function

1994 • 75 citations

Substrate specificity of the Escherichia coli RuvC protein. Resolution of three- and four-stranded recombination intermediates.

1994 • 74 citations

Homologous Association of Chromosomal DNA during Yeast Meiosis

1983 • 71 citations

Holliday Junction Crossover Topology

1994 • 69 citations

RuvC protein resolves Holliday junctions via cleavage of the continuous (noncrossover) strands.

1995 • 68 citations

Resolution of Holliday Structures by Endonuclease VII As Observed in Interactions with Cruciform DNA

1984 • 68 citations

Tests of the Double-Strand-Break Repair Model for Red-Mediated Recombination of Phage Λ and Plasmid Λdv

1987 • 66 citations

Recombination in the eukaryotic nucleus

1988 • 66 citations

Initiation of heteroduplex-loop repair by T4-encoded endonuclease VII in vitro.

1988 • 62 citations

Mismatch repair and the fidelity of genetic recombination

1989 • 49 citations

Activation of RuvC Holliday junction resolvasein vitro

1994 • 46 citations

Mitotic versus meiotic recombination in Saccharomyces cerevisiae

1980 • 36 citations

Concerning the Stereochemistry of Strand Equivalence in Genetic Recombination

1974 • 30 citations

Genetic evidence for preferential strand transfer during meiotic recombination in yeast.

1990 • 28 citations

Meiosis: DNA branching during meiotic recombination

1994 • 5 citations

[11] Physical monitoring of mitotic and meiotic recombination in Saccharomyces cerevisiae

1995 • 1 citations