Meiosis-Specific Double-Strand DNA Breaks at the HIS4 Recombination Hot Spot in the Yeast Saccharomyces cerevisiae: Control in cis and trans

Methods in yeast genetics

1979 • 7,824 citations

Methods in Yeast Genetics

1988 • 4,905 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

The double-strand-break repair model for recombination

1983 • 2,468 citations

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

1984 • 2,401 citations

The molecular biology of the yeast saccharomyces

1982 • 1,165 citations

[12] High-efficiency transformation of yeast by electroporation

1991 • 798 citations

Replacement of chromosome segments with altered DNA sequences constructed in vitro.

1979 • 779 citations

A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae

1990 • 683 citations

Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination

1990 • 591 citations

BIOCHEMICAL MUTANTS IN THE SMUT FUNGUS USTILAGO MAYDIS

1949 • 579 citations

Double-strand breaks at an initiation site for meiotic gene conversion

1989 • 533 citations

Extensive 3′-overhanging, single-stranded DNA associated with the meiosis-specific double-strand breaks at the ARG4 recombination initiation site

1991 • 525 citations

Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae.

1988 • 511 citations

Meiosis-Induced Double-Strand Break Sites Determined by Yeast Chromatin Structure

1994 • 433 citations

RECOMBINATION IN YEAST

1971 • 405 citations

GCN4 protein, a positive transcription factor in yeast, binds general control promoters at all 5' TGACTC 3' sequences.

1986 • 320 citations

An initiation site for meiotic gene conversion in the yeast Saccharomyces cerevisiae

1989 • 305 citations

Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast

1992 • 280 citations

DNA double-strand breaks and the RAD50-RAD57 genes in Saccharomyces.

1993 • 249 citations

Multiple Global Regulators Control HIS4 transcription in Yeast

1987 • 246 citations

Meiosis and Ascospore Development

1981 • 209 citations

Activation of meiosis and sporulation by repression of the RME1 product in yeast

1986 • 186 citations

Palindromic sequences in heteroduplex DNA inhibit mismatch repair in yeast

1989 • 165 citations

DNA sequence analysis of the ade6 gene of Schizosaccharomyces pombe

1988 • 163 citations

REGULATION OF MATING AND MEIOSIS IN YEAST BY THE MATING-TYPE REGION

1976 • 159 citations

RAP1 is required for BAS1/BAS2- and GCN4-dependent transcription of the yeast HIS4 gene.

1991 • 147 citations

Multiple sites for double-strand breaks in whole meiotic chromosomes of Saccharomyces cerevisiae.

1992 • 135 citations

Timing of molecular events in meiosis in Saccharomyces cerevisiae: stable heteroduplex DNA is formed late in meiotic prophase.

1993 • 134 citations

Transcription factors are required for the meiotic recombination hotspot at the HIS4 locus in Saccharomyces cerevisiae.

1993 • 129 citations

Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae.

1992 • 126 citations

DNA-binding protein RAP1 stimulates meiotic recombination at the HIS4 locus in yeast.

1991 • 98 citations

Decreasing gradients of gene conversion on both sides of the initiation site for meiotic recombination at the ARG4 locus in yeast.

1990 • 96 citations

Genetic and physical analysis of the M26 recombination hotspot of Schizosaccharomyces pombe.

1988 • 94 citations

Physical detection of heteroduplexes during meiotic recombination in the yeast Saccharomyces cerevisiae.

1993 • 92 citations

Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break.

1993 • 88 citations

Initiation of recombination in Saccharomyces cerevisiae haploid meiosis.

1994 • 80 citations

A short chromosomal region with major roles in yeast chromosome III meiotic disjunction, recombination and double strand breaks.

1993 • 79 citations

A promoter deletion reduces the rate of mitotic, but not meiotic, recombination at the HIS4 locus in yeast

1992 • 78 citations

Seven-base-pair inverted repeats in DNA form stable hairpins in vivo in Saccharomyces cerevisiae.

1991 • 77 citations

The control in cis of the position and the amount of the ARG4 meiotic double-strand break of Saccharomyces cerevisiae.

1993 • 71 citations

Repair of specific base pair mismatches formed during meiotic recombination in the yeast Saccharomyces cerevisiae.

1991 • 71 citations

MATING TYPE AND SPORULATION IN YEAST I. MUTATIONS WHICH ALTER MATING-TYPE CONTROL OVER SPORULATION

1975 • 65 citations

The Tn3 beta-lactamase gene acts as a hotspot for meiotic recombination in yeast.

1991 • 56 citations

Measurements of excision repair tracts formed during meiotic recombination in Saccharomyces cerevisiae.

1992 • 46 citations

Initiation of meiotic recombination is independent of interhomologue interactions.

1994 • 44 citations

Analysis of a recombination hotspot for gene conversion occurring at the HIS2 gene of Saccharomyces cerevisiae.

1994 • 41 citations

Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae.

1991 • 31 citations