Central opioid receptor subtype antagonists differentially reduce intake of saccharin and maltose dextrin solutions in rats

The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

1976 • 2,883 citations

Endogenous opioid peptides: multiple agonists and receptors

1977 • 2,494 citations

Binaltorphimine and nor-binaltorphimine, potent and selective k-opioid receptor antagonists

1987 • 529 citations

Opioid modulation of appetite

1983 • 452 citations

Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays.

1988 • 399 citations

Minireview: Multiple MU opiate receptors

1986 • 348 citations

Kappa opiate receptor multiplicity: evidence for two U50,488-sensitive kappa 1 subtypes and a novel kappa 3 subtype.

1989 • 331 citations

Application of the message-address concept in the design of highly potent and selective non-peptide .delta. opioid receptor antagonists

1988 • 298 citations

A novel opioid receptor site directed alkylating agent with irreversible narcotic antagonistic and reversible agonistic activities

1980 • 287 citations

Suppression of deprivation-induced food and water intake in rats and mice by naloxone

1979 • 282 citations

Carbohydrate taste, appetite, and obesity: An overview

1987 • 256 citations

The irreversible narcotic antagonistic and reversible agonistic properties of the fumaramate methyl ester derivative of naltrexone

1981 • 229 citations

Opioids and consummatory behavior

1985 • 182 citations

Irreversible opiate agonists and antagonists: the 14-hydroxydihydromorphinone azines.

1982 • 164 citations

Irreversible opiate agonists and antagonists: the 14- hydroxydihydromorphinone azines

1982 • 156 citations

Flavor enhances the antidipsogenic effect of naloxone

1982 • 150 citations

Pain modulating and reward systems: A single brain mechanism?

1980 • 148 citations

Effects of narcotic antagonists on fluid intake in the rat

1975 • 143 citations

Qualitative differences in polysaccharide and sugar tastes in the rat: A two-carbohydrate taste model

1987 • 142 citations

Effects of opiate agonists and antagonists on fluid intake and saccharin choice in the rat

1983 • 131 citations

Naloxone attenuation of sham feeding is modified by manipulation of sucrose concentration

1988 • 124 citations

Amphetamine- and morphine-induced feeding: Evidence for involvement of reward mechanisms

1990 • 121 citations

Modifications of nutrient selection induced by naloxone in rats

1981 • 118 citations

Opiate blockade inhibits saccharin intake and blocks normal preference acquisition

1986 • 117 citations

Morphine selectively influences macronutrient intake in the rat

1980 • 115 citations

Endorphins and food intake: Kappa opioid receptor agonists and hyperphagia

1985 • 115 citations

Naloxone modifies sugar-water intake in rats drinking with open gastric fistulas

1982 • 111 citations

Increased fat consumption induced by morphine administration in rats

1982 • 109 citations

The effects of morphine on diet selection are dependent upon baseline diet preferences

1990 • 108 citations

Centrally administered opioid peptides stimulate saccharin intake in nondeprived rats

1989 • 100 citations

Dual Action of Naloxone on Feeding Revealed by Behavioural Analysis: Separate Effects on Initiation and Termination of Eating

1984 • 97 citations

Naloxone suppresses intake of highly preferred saccharin solutions in food deprived and sated rats

1983 • 97 citations

Carbohydrate taste preferences in rats: Glucose, sucrose, maltose, fructose and polycose compared

1987 • 95 citations

Attenuation of sham feeding by naloxone is stereospecific: Evidence for opioid mediation of orosensory reward

1988 • 93 citations

Nor-binaltorphimine decreases deprivation and opioid-induced feeding

1990 • 91 citations

Central opioid receptor subtype antagonists differentially alter sucrose and deprivation-induced water intake in rats

1992 • 87 citations

Suppression of nocturnal, palatable and glucoprivic intake in rats by the κ opioid antagonist, nor-binaltorphamine

1990 • 87 citations

Affinity labeling of delta-opiate receptors using [D-Ala2,Leu5,Cys6]enkephalin. Covalent attachment via thiol-disulfide exchange.

1987 • 81 citations

Effect of naloxone and naltrexone on the development of satiation measured in the runway: Comparisons with d-amphetamine and d-fenfluramine

1986 • 79 citations

Morphine and acceptability of putative reinforcers

1983 • 79 citations

Evidence for two subtypes of δ opioid receptors in rat brain

1991 • 79 citations

Reduction by central ß-funaltrexamine of food intake in rats under freely-feeding, deprivation and glucoprivic conditions

1990 • 79 citations

Hedonic response of rats to polysaccharide and sugar solutions

1987 • 76 citations

Effects of Kappa Opiate Agonists, Cholecystokinin and Bombesin on Intake of Diets Varying in Carbohydrate-to-Fat Ratio in Rats

1987 • 72 citations

Sham-Feeding response of rats to polycose and sucrose

1987 • 72 citations

Why do sugars taste good?

1990 • 72 citations

Morphine-stimulated feeding: Analysis of macronutrient selection and paraventricular nucleus lesions

1986 • 70 citations

Taste preference thresholds for polycose, maltose, and sucrose in rats

1987 • 66 citations

Selective opioid receptor antagonist effects upon intake of a high-fat diet in rats

1990 • 65 citations

Endophinergic modulation of acceptability of putative reinforcers

1983 • 64 citations

Evidence for opiate receptor involvement in the consumption of a high palatability diet in nondeprived rats

1985 • 64 citations

Demonstrating morphine's potentiating effects on sucrose-intake

1986 • 63 citations

Reduced saccharin preference in CXBK (opioid receptor-deficient) mice

1988 • 55 citations

Morphine-elicited feeding: Diurnal rhythm, circulating corticosterone and macronutrient selection

1986 • 53 citations

Ingestive behavior following central [D-Ala2, Leu5, Cys6]-Enkephalin (DALCE), a short-acting agonist and long-acting antagonist at the delta opioid receptor

1991 • 53 citations

Central and peripheral contributions of endogenous opioid systems to nutrient selection in rats

1985 • 49 citations

The κ opioid receptor and food intake

1985 • 48 citations

Are δ-opioid receptors involved in the regulation of food and water intake?

1985 • 48 citations

Diet selection following a chronic morphine and naloxone regimen

1990 • 47 citations

Effects of kappa opiate agonists on palatable food consumption in non-deprived rats, with and without food preloads

1985 • 44 citations

Effects of naloxone and its quaternary analogue on fluid consumption in water-deprived rats

1983 • 43 citations

Influence of saccharide length on polysaccharide appetite in the rat

1987 • 41 citations

Centrally administered opioid antagonists, nor-binaltorphimine, 16-methyl cyprenorphine and MR2266, suppress intake of a sweet solution

1990 • 38 citations

Opioid agonist and antagonist antinociceptive properties of [D-Ala2,Leu5,Cys6]enkephalin: selective actions at the deltanoncomplexed site.

1990 • 36 citations

Suppression of deprivation-induced water intake in the rat by opioid antagonists: central sites of action

1987 • 32 citations

Mediation of insulin hyperphagia by specific central opiate receptor antagonists

1991 • 32 citations

Involvement of mu1 and mu2 opioid receptor subtypes in tail-pinch feeding in rats

1993 • 31 citations

Sugar taste reception in mammals

1988 • 29 citations

Sucrose-induced hyperphagia and obesity in rats fed a macronutrient self-selection diet

1988 • 27 citations

Neurologic deficits and neuronal injury in rats resulting from nonopioid actions of the delta opioid receptor antagonist ICI 174864.

1988 • 20 citations

The taste characteristics of sodium-saccharin in the rat: a re-examination of the dual taste hypothesis

1988 • 9 citations