Resistance to Levofloxacin and Failure of Treatment of Pneumococcal Pneumonia

Practice Guidelines for the Management of Community-Acquired Pneumonia in Adults

2000 • 2,295 citations

Guidelines for the Management of Adults with Community-acquired Pneumonia

2001 • 2,114 citations

Decreased Susceptibility ofStreptococcus pneumoniaeto Fluoroquinolones in Canada

1999 • 1,012 citations

Canadian Guidelines for the Initial Management of Community-Acquired Pneumonia: An Evidence-Based Update by the Canadian Infectious Diseases Society and the Canadian Thoracic Society

2000 • 660 citations

Management of Community-Acquired Pneumonia in the Era of Pneumococcal Resistance

2000 • 629 citations

Pharmacodynamics of Levofloxacin

1998 • 583 citations

Bacterial infection in chronic obstructive pulmonary disease. A study of stable and exacerbated outpatients using the protected specimen brush.

1995 • 562 citations

Comparison of genomic DNAs of different enterococcal isolates using restriction endonucleases with infrequent recognition sites

1990 • 524 citations

Mechanisms of Action of Antimicrobials: Focus on Fluoroquinolones

2001 • 467 citations

A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in treatment of adults with community-acquired pneumonia

1997 • 367 citations

Emergence of Fluoroquinolone Resistance among Multiply Resistant Strains of Streptococcus pneumoniae in Hong Kong

1999 • 241 citations

Risk Factors for Acquisition of Levofloxacin-Resistant Streptococcus pneumoniae: A Case-Control Study

2001 • 217 citations

Pharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous doses

1997 • 216 citations

Analysis for a Limited Number of Gene Codons Can Predict Drug Resistance of Mycobacterium tuberculosis in a High-Incidence Community

2001 • 163 citations

Oral Moxifloxacin vs High-Dosage Amoxicillin in the Treatment of Mild-to-Moderate, Community-Acquired, Suspected Pneumococcal Pneumonia in Adults

2001 • 129 citations

Fluoroquinolone Resistance in Clinical Isolates of Streptococcus pneumoniae : Contributions of Type II Topoisomerase Mutations and Efflux to Levels of Resistance

2000 • 122 citations

A Nosocomial Outbreak of Fluoroquinolone‐ResistantStreptococcus pneumoniae

2001 • 116 citations

Pharmacodynamics of Trovafloxacin, Ofloxacin, and Ciprofloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model

1999 • 73 citations

Analysis of Ciprofloxacin Activity against Streptococcus pneumoniae after 10 Years of Use in the United States

2000 • 69 citations

THE SPECIFIC POLYSACCHARIDE CONTENT OF PNEUMONIC LUNGS

1942 • 56 citations

Evaluation of Susceptibility Testing To Detect Fluoroquinolone Resistance Mechanisms in Streptococcus pneumoniae

2001 • 38 citations