Macrophage lineage switching of murine early pre-B lymphoid cells expressing transduced fms genes.

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

The Granulocyte-Macrophage Colony-Stimulating Factors

1985 • 1,007 citations

Interleukin 6 enhancement of interleukin 3-dependent proliferation of multipotential hemopoietic progenitors.

1987 • 847 citations

Stimulation of B-cell progenitors by cloned murine interleukin-7

1988 • 826 citations

Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells.

1977 • 740 citations

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

1988 • 727 citations

Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity

1983 • 702 citations

Intracellular localization of messenger RNAs for cytoskeletal proteins

1986 • 639 citations

Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes

1989 • 610 citations

Lineage promiscuity in hemopoietic differentiation and leukemia

1986 • 572 citations

CSF‐1—A mononuclear phagocyte lineage‐specific hemopoietic growth factor

1983 • 536 citations

Direct activation of the serine/threonine kinase activity of raf-1 through tyrosine phosphorylation by the PDGF β-receptor

1989 • 513 citations

Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus

1986 • 478 citations

cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor.

1989 • 413 citations

B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors.

1988 • 379 citations

Colony-stimulating factor-1 receptor

1990 • 362 citations

Transforming potential of the c-fms proto-oncogene (CSF-1 receptor)

1987 • 357 citations

Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites

1978 • 342 citations

Stem cells in normal and leukemic hemopoiesis (Henry Stratton Lecture, 1982)

1983 • 304 citations

Regulation of very primitive, multipotent, hemopoietic cells by hemopoietin-1

1986 • 283 citations

Specific interaction of murine colony-stimulating factor with mononuclear phagocytic cells.

1980 • 265 citations

A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential

1988 • 242 citations

Distribution of cells bearing receptors for a colony-stimulating factor (CSF-1) in murine tissues.

1981 • 239 citations

Disparate differentiation in mouse hemopoietic colonies derived from paired progenitors.

1984 • 233 citations

PROMOTION OF REPLICATION IN LYMPHOID CELLS BY SPECIFIC THIOLS AND DISULFIDES IN VITRO

1973 • 225 citations

A single bone marrow-derived stromal cell type supports the in vitro growth of early lymphoid and myeloid cells

1987 • 207 citations

Synthesis of membrane-bound colony-stimulating factor 1 (CSF-1) and downmodulation of CSF-1 receptors in NIH 3T3 cells transformed by cotransfection of the human CSF-1 and c-fms (CSF-1 receptor) genes.

1987 • 202 citations

Synergism between hemopoietic growth factors (HGFs) detected by their effects on cells bearing receptors for a lineage specific HGF: Assay of hemopoietin‐1

1985 • 184 citations

Proliferation of Haemopoietic Stem Cells in Vitro

1974 • 181 citations

Hemopoietic lineage switch: v-raf oncogene converts Eμmyc transgenic B cells into macrophages

1988 • 179 citations

Structure-function studies of a colony stimulating factor (CSF-1).

1982 • 175 citations

Tandem linkage of human CSF-1 receptor (c-fms) and PDGF receptor genes

1988 • 172 citations

Activation of the feline c-fms proto-oncogene: Multiple alterations are required to generate a fully transformed phenotype

1988 • 164 citations

The Product of the c- fms Proto-Oncogene: a Glycoprotein with Associated Tyrosine Kinase Activity

1985 • 162 citations

Self-renewal of hemopoietic stem cells during mixed colony formation in vitro.

1981 • 153 citations

Clonal analysis of proliferation and differentiation of paired daughter cells: action of granulocyte-macrophage colony-stimulating factor on granulocyte-macrophage precursors.

1980 • 147 citations

Clonal analysis of progenitor cell commitment to granulocyte or macrophage production

1982 • 145 citations

Cell Surface Expression of v-fms-Coded Glycoproteins Is Required for Transformation

1984 • 131 citations

Murine hematopoietic cells with pre-B or pre-B/myeloid characteristics are generated by in vitro transformation with retroviruses containing fes, ras, abl, and src oncogenes.

1986 • 124 citations

Purification of the colony-stimulating factor 1 receptor and demonstration of its tyrosine kinase activity.

1987 • 123 citations

Derivation of macrophage-like lines from the pre-B lymphoma ABLS 8.1 using 5-azacytidine

1982 • 121 citations

Subcellular localization of glycoproteins encoded by the viral oncogene v-fms

1984 • 115 citations

Murine c-fms cDNA: cloning, sequence analysis and retroviral expression.

1987 • 113 citations

Relationships between B cell and myeloid differentiation. Studies with a B lymphocyte progenitor line, HAFTL-1.

1988 • 111 citations

Differential Processing of Colony-Stimulating Factor 1 Precursors Encoded by Two Human cDNAs

1988 • 103 citations

Monoclonal antibodies to the human CSF-1 receptor (c-fms proto-oncogene product) detect epitopes on normal mononuclear phagocytes and on human myeloid leukemic blast cells

1989 • 94 citations

Induction of macrophage colony-stimulating factor-dependent growth and differentiation after introduction of the murine c-fms gene into FDC-P1 cells.

1989 • 88 citations

Macrophage colony formation supported by purified CSF-1 and/or interleukin 3 in serum-free culture: evidence for hierarchical difference in macrophage colony-forming cells

1986 • 84 citations

A mouse c-myc retrovirus transforms established fibroblast lines in vitro and induces monocyte-macrophage tumors in vivo

1986 • 65 citations

Molecular and biological properties of a macrophage colony-stimulating factor from mouse yolk sacs

1978 • 62 citations

Colony Stimulating Factor-1

1990 • 58 citations

Colony-Stimulating Factor 1 (Macrophage Colony-Stimulating-Factor)

1991 • 57 citations

Inhibition of colony-stimulating factor-1 activity by monoclonal antibodies to the human CSF-1 receptor

1989 • 50 citations

Isotype switching in human B lymphocyte malignancies occurs by DNA deletion: evidence for nonspecific switch recombination.

1987 • 46 citations

Long-term culture of murine bone marrow precursors of B lymphocytes

1987 • 45 citations

Clonal lymphoid progenitor cell lines expressing the BCR/ABL oncogene retain full differentiative function.

1990 • 44 citations

Antibodies to distal carboxyl terminal epitopes in the v-fms-coded glycoprotein do not cross-react with the c-fms gene product

1986 • 44 citations

Induction of Clonal Monocyte-Macrophage Tumors in Vivo by a Mouse c-myc Retrovirus: Rearrangement of the CSF-1 Gene as a Secondary Transforming Event

1987 • 44 citations

Synthesis, post-translational processing, and autocrine transforming activity of a carboxylterminal truncated form of colony stimulating factor-1.

1987 • 34 citations

Transduction of Human Colony-Stimulating Factor-1 (CSF-1) Receptor into Interleukin-3-Dependent Mouse Myeloid Cells Induces Both CSF-1-Dependent and Factor-Independent Growth

1989 • 31 citations

Early pre-B-cell transformation induced by the v-fms oncogene in long-term mouse bone marrow cultures.

1989 • 25 citations